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Cat. No.: HY-P11284

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TGN

TGN, a 12-amino acid ligand, is a BBB-penetrating peptide. TGN can be used as a drug delivery vehicle for Alzheimer's disease research.

For research use only. We do not sell to patients.

CAS No.: 1312882-14-6
Formula: C₅₇H₈₅N₁₉O₁₇
Molecular Weight:1308.40

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

TGN Chemical Structure

CAS No.: 1312882-14-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

TGN, a 12-amino acid ligand, is a BBB-penetrating peptide. TGN can be used as a drug delivery vehicle for Alzheimer's disease research^[1].

Chemical Information

CAS No. 1312882-14-6
Molecular Weight 1308.40
Formula C₅₇H₈₅N₁₉O₁₇
Sequence

Thr-Gly-Asn-Tyr-Lys-Ala-Leu-His-Pro-His-Asn-Gly
Sequence Shortening

TGNYKALHPHNG
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Animals and Diseases

Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (256 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Gu J, et al. Erythrocyte membrane-coated nanocarriers modified by TGN for Alzheimer's disease. J Control Release. 2024 Feb;366:448-459. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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