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VHL Ligand 38

VHL Ligand 38 (Compound 1) is a competitive E3 ubiquitin-protein ligase VHL inhibitor with IC50s of 4.1 and 7.0 μM in 1% and 10% DMSO, respectively. VHL Ligand 38 contains a hydroxyproline residue and an isoxazolylacetamide fragment. VHL Ligand 38 significantly inhibits the binding of a fluorescent peptide derived from HIF1α (FAM-DEALA-Hyp-YIPD) (HY-P5908F) to VHL.

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  • CAS 番号: 1360616-29-0
  • 分子式: C21H22N4O5
  • 分子量:410.42
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • VHL Ligand 38 Chemical Structure
    VHL Ligand 38 構造式
CAS 番号: 1360616-29-0
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