Cys-FAP targeting peptide for FXX489 TFA
Based on 1 Customer Validation
Cys-FAP targeting peptide for FXX489 TFA is a version of the FAP-targeting peptide for FXX489 TFA that incorporates a Cys (cysteine) group. It can undergo conjugation reactions via the thiol group of the cysteine residue.
For research use only. We do not sell to patients.
- Purity : 95.77%
- Formula: C70H96N16O16S·xC2HF3O2
- Molecular Weight:1449.67 (free base)
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All Radionuclide-Drug Conjugates (RDCs) Isoforms
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Biological Activity
Description
In Vitro
Cys-FAP targeting peptide for FXX489 TFA is labeled with Cys and can form Unlabeled FXX489; it targets fibroblast activation protein (FAP), thereby exhibiting pan-cancer inhibitory activity. When labeled with 68Ga or 177Lu, Unlabeled FXX489 demonstrates favorable tumor retention and anti-tumor activity across various types of cancer[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 1449.67 (free base)
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Formula C70H96N16O16S·xC2HF3O2
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Color White to off-white
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
H2O : ≥ 50 mg/mL
* "≥" means soluble, but saturation unknown.
Purity & Documentation
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Data Sheet (286 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)