FAP targeting peptide for FXX489
Based on 1 Customer Validation
FAP targeting peptide for FXX489 is the polypeptide part of Unlabeled FXX489 (HY-P10944). Unlabeled FXX489 is a fibroblast activation protein (FAP)-targeting ligand.
For research use only. We do not sell to patients.
- Purity: 99.49%
- CAS No.: 3076328-74-7
- Formula: C67H91N15O15
- Molecular Weight:1346.53
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All Radionuclide-Drug Conjugates (RDCs) Isoforms
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Biological Activity
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RDC Peptide |
FAP targeting peptide for FXX489 can form Unlabeled FXX489, which can target fibroblast activation protein (FAP) and thus possesses pan-cancer inhibitory activity. After being labeled with 68Ga and 177Lu, Unlabeled FXX489 has good tumor retention and anti-tumor activity in various cancers[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3076328-74-7
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Appearance Solid
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Molecular Weight 1346.53
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Formula C67H91N15O15
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Color White to off-white
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (74.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (280 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7426 mL | 3.7132 mL | 7.4265 mL | 18.5662 mL |
| 5 mM | 0.1485 mL | 0.7426 mL | 1.4853 mL | 3.7132 mL | |
| 10 mM | 0.0743 mL | 0.3713 mL | 0.7426 mL | 1.8566 mL | |
| 15 mM | 0.0495 mL | 0.2475 mL | 0.4951 mL | 1.2377 mL | |
| 20 mM | 0.0371 mL | 0.1857 mL | 0.3713 mL | 0.9283 mL | |
| 25 mM | 0.0297 mL | 0.1485 mL | 0.2971 mL | 0.7426 mL | |
| 30 mM | 0.0248 mL | 0.1238 mL | 0.2475 mL | 0.6189 mL | |
| 40 mM | 0.0186 mL | 0.0928 mL | 0.1857 mL | 0.4642 mL | |
| 50 mM | 0.0149 mL | 0.0743 mL | 0.1485 mL | 0.3713 mL | |
| 60 mM | 0.0124 mL | 0.0619 mL | 0.1238 mL | 0.3094 mL |