1. Peptides
  2. R18 TFA

R18 TFA (Synonyms: PHCVPRDLSWLDLEANMCLP TFA)

Cat. No.: HY-P1039A
Handling Instructions

R18 TFA is a peptide antagonists of 14-3-3, with a KD of 70-90 nM. R18 efficiently blocks the binding of 14-3-3 to the kinase Raf-1, a physiological ligand of 14-3-3, and effectively abolished the protective role of 14-3-3 against phosphatase-induced inactivation of Raf-1.

For research use only. We do not sell to patients.

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R18 TFA Chemical Structure

R18 TFA Chemical Structure

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Other Forms of R18 TFA:

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Description

R18 TFA is a peptide antagonists of 14-3-3, with a KD of 70-90 nM. R18 efficiently blocks the binding of 14-3-3 to the kinase Raf-1, a physiological ligand of 14-3-3, and effectively abolished the protective role of 14-3-3 against phosphatase-induced inactivation of Raf-1[1].

Molecular Weight

2423.73

Formula

C₁₀₃H₁₅₈F₃N₂₇O₃₁S₃

Sequence

Pro-His-Cys-Val-Pro-Arg-Asp-Leu-Ser-Trp-Leu-Asp-Leu-Glu-Ala-Asn-Met-Cys-Leu-Pro

Sequence Shortening

PHCVPRDLSWLDLEANMCLP

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

R18PHCVPRDLSWLDLEANMCLPR 18R-18OthersInhibitorinhibitorinhibit

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R18 TFA
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