2. Metabolic Enzyme/Protease
  3. Liposome
  4. DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY

DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery.

For research use only. We do not sell to patients.

DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY

DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY Chemical Structure

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Based on 1 publication(s) in Google Scholar

DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY Related Antibodies

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Description

DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery[1].

In Vitro

DSPE-PEG-Mal-Cys-YEQDPWGVKWWY consists of three parts: a hydrophobic 1,2-distearate-sn-glycerol-3-phosphate ethanolamine (DSPE), a hydrophilic PEG chain, and a terminally modified M2pep targeting peptide (YEQDPWGVKWWY). This amphiphilic structure facilitates its embedding in the lipid bilayer while exposing the M2pep peptide on its outer surface, enabling the recognition of surface markers on M2 macrophages. It is noteworthy that the choice of PEG chain length (e.g., PEG2000) significantly affects blood circulation time and steric hindrance effects, requiring optimization based on specific experimental models.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY Related Antibodies
Molecular Weight

2000 (Average)

Appearance

Solid

Color

White to off-white

SMILES

[Mal-Cys-YEQDPWGVKWWY]C(CCOCCOC(NCCOP(OC[C@](COC(CCCCCCCCCCCCCCCCC)=O)([H])OC(CCCCCCCCCCCCCCCCC)=O)(O)=O)=O)=O.[n]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

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Purity & Documentation
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DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWYLiposomeInhibitorinhibitorinhibit

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Product Name:
DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY
Cat. No.:
HY-172273A
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