2. Search Result
Search Result
Results for "

dosing agent

" in MedChemExpress (MCE) Product Catalog:

129

Inhibitors & Agonists

2

Fluorescent Dyes

2

Biochemical Assay Reagents

26

Natural
Products

9

Isotope-Labeled Compounds

4

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0094
    Artemisinin
    Maximum Cited Publications
    32 Publications Verification

    Qinghaosu; NSC 369397

    		 HCV Parasite Akt Ferroptosis Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants . Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects .
    Artemisinin
  • HY-B0006
    Carvedilol
    10+ Cited Publications

    BM 14190

    		 Adrenergic Receptor Autophagy Bacterial Cardiovascular Disease Inflammation/Immunology Cancer
    Carvedilol (BM 14190) is a non-selective β/α-1 blocker . Carvedilol inhibits lipid peroxidation in a dose-dependent manner with an IC50 of 5 μM. Carvedilol is a multiple action antihypertensive agent with potential use in angina and congestive heart failure . Carvedilol is an autophagy inducer that inhibits the NLRP3 inflammasome .
    Carvedilol
  • HY-10119
    Vorapaxar
    10+ Cited Publications

    SCH 530348

    		 Protease Activated Receptor (PAR) Cardiovascular Disease
    Vorapaxar (SCH 530348), an antiplatelet agent, is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist (Ki=8.1 nM). Vorapaxar (SCH 530348) inhibits thrombin receptor-activating peptide (TRAP)-induced platelet aggregation in a dose-dependent manner .
    Vorapaxar
  • HY-11062
    Icilin
    1 Publications Verification

    AG-3-5

    		 TRP Channel Neurological Disease Inflammation/Immunology
    Icilin (AG-3-5) is a super-agonist of the transient receptor potential M8 (TRPM8) ion channel. Icilin activates TRPM8 in EGTA in a dose-dependent manner (EC50=1.4 μM). Icilin is a "super-cooling agent" . Icilin attenuates autoimmune neuroinflammation through modulation of the T-cell response .
    Icilin
  • HY-N0407
    Picroside I

    6'-Cinnamoylcatalpol

    		 STAT Inflammation/Immunology
    Picroside I is the major ingredient of Picrorhiza scrophulariiflora. Picrorhiza scrophulariiflora is a high value medicinal herb due to rich source of hepatoprotective metabolites, Picroside-I and Picroside-II . Picroside I is a promising agent for the management of asthma. Picroside I reduces the inflammation significantly at its higher dose. Picroside I also downregulates pSTAT6 and GATA3 expressions. Picroside I dose-dependently increases the serum levels of IFN-γ .
    Picroside I
  • HY-B0920
    Tolazamide
    2 Publications Verification

    U-17835

    		 Potassium Channel Metabolic Disease Endocrinology
    Tolazamide (U-17835) is an orally active sulfonylurea agent that inhibits sulfonylurea receptor 1 (SUR1) linked to the inwardly rectifying potassium channel (IC50 = 4.2 µM in HEK293 cells transfected with the human receptor). Tolazamide has anti-diabetic properties. Tolazamide can lower blood glucose in sulfonylurea class. Tolazamide decreases insulin dose while continuing to maintain adequate metabolic control. Tolazamide is able to improve or normalize hyperglycemia and HbA .
    Tolazamide
  • HY-N3017
    Artemitin
    1 Publications Verification

    		 Antibiotic Neurological Disease Inflammation/Immunology
    Artemitin is a flavonoid neuroanesthetic agent with moderate cytotoxicity. Artemitint has selective inhibitory activity against Meth-A sarcoma cells with an ED50 of 5-10 μg/mL, and has no significant effect on LLC lung cancer cells. Artemitin exerts anticancer activity by affecting cell proliferation signaling pathways, and also has potential anti-inflammatory and neuroprotective effects. Artemitin exhibits a dose-dependent antinociceptive effect in the mouse hot plate test, with an ED50 of 1.6 μg/kg, and has analgesic activity .
    Artemitin
  • HY-127009
    Levoleucovorin

    Levofolinic acid; Levofolene

    		 Lysyl Oxidase Apoptosis Metabolic Disease Cancer
    Levoleucovorin (Levofolinic acid; Levofolene) is the pharmacologically and orally active levoisomer of Folinic acid (HY-17556), a synthetic folate analogue. Levoleucovorin can inhibit LOXL2 with an IC50 of 68.81 μM. Levoleucovorin can inhibit cancer cells proliferation, migration and induce apoptosis. Levoleucovorin can be used as a rescue agent for high-dose Methotrexate (HY-14519). Levoleucovorin can reduce the frequency of embryonic malformations. Levoleucovorin can be used for the research of can and endocrinology, such as breast cancer and osteosarcoma .
    Levoleucovorin
  • HY-12624
    Narazaciclib
    2 Publications Verification

    ON123300

    		 CDK AMPK PDGFR Cancer
    Narazaciclib (ON123300), a strong and brain-penetrant multi-kinase inhibitor, inhibits CDK4 (IC50=3.9 nM), Ark5 (IC50=5 nM), PDGFRβ (IC50=26 nM), FGFR1 (IC50=26 nM), RET (IC50=9.2 nM), and FYN (IC50=11 nM). Single agent Narazaciclib causes a dose-dependent suppression of phosphorylation of Akt as well as activation of Erk in brain tumors . Narazaciclib inhibits CDK6 with an IC50 of 9.82 nM .
    Narazaciclib
  • HY-N0340
    Scopolamine butylbromide
    1 Publications Verification

    Hyoscine butylbromide; (-)-Scopolamine butylbromide; Butylscopolamine bromide

    		 mAChR Neurological Disease Inflammation/Immunology
    Scopolamine butylbromide (Hyoscine butylbromide) is an orally active anticholinergic agent and spasmolytic. Scopolamine butylbromide binds with high affinity to rat cardiac M2 (Ki 83 nmol/L), hM2 (Ki 233 nmol/L), rat intestinal M3 (Ki 290 nmol/L) and hM3 (Ki 643 nmol/L) muscarinic receptors. Scopolamine butylbromide exerts a dose-dependent antagonistic effect on Carbachol-induced gastrointestinal smooth muscle spasm. Scopolamine butylbromide can be used for the research of abdominal colic and pain associated with gastrointestinal spasm, functional abdominal pain, chronic gastropathy and gastric ulcer .
    Scopolamine butylbromide
  • HY-B1246
    Thonzonium bromide
    5+ Cited Publications

    		 Bacterial Proton Pump Infection
    Thonzonium bromide is an antibacterial agent that is structurally similar to Farnesol (HY-Y0248A). Thonzonium bromide is also a monocationic surface-active agent, which inhibits RANKL-induced osteoclast formation and bone resorption in vitro and prevents LPS-induced bone loss in vivo. Thonzonium bromide inhibits proton transport in a dose-dependent manner (EC50=69 μM) .
    Thonzonium bromide
  • HY-10119A
    Vorapaxar sulfate
    10+ Cited Publications

    SCH 530348 sulfate

    		 Protease Activated Receptor (PAR) Cardiovascular Disease
    Vorapaxar sulfate (SCH 530348 sulfate), an antiplatelet agent, is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist (Ki=8.1 nM). Vorapaxar sulfate inhibits thrombin receptor-activating peptide (TRAP)-induced platelet aggregation in a dose-dependent manner .
    Vorapaxar sulfate
  • HY-Y1282
    Sodium tetraborate decahydrate

    		Environmental Pollutants Biochemical Assay Reagents SOD Cardiovascular Disease Infection Neurological Disease
    Sodium tetraborate decahydrate is an orally active biochemical reagent and antibacterial agent. Sodium tetraborate decahydrate leads to an increase in the activity of Catalase, Superoxide dismutase. Sodium tetraborate decahydrate reduces Hydrogen sulfide and the sulfate-reducing bacteria population of swine manure. Sodium tetraborate decahydrate serves as flame suppressant for wood cellulose. Sodium tetraborate decahydrate is a triglyceride transesterification catalyst. Sodium tetraborate decahydrate suppresses the formation of chlorinated by-products in Cl −-containing water. Sodium tetraborate decahydrate has a neuroprotective effect against chromium poisoning. Sodium tetraborate decahydrate can protect the heart from chromium damage at low doses. Sodium tetraborate in a low dose with an isolated application shows an antioxidant effect .
    Sodium tetraborate decahydrate
  • HY-12443
    PF-5006739

    		Casein Kinase Neurological Disease
    PF-5006739 is a potent and selective inhibitor of CK1δ/ε with IC50s of 3.9 nM and 17.0 nM, respectively. PF-5006739 is a potential therapeutic agent for a range of psychiatric disorders with low nanomolar in vitro potency for CK1δ/ε and high kinome selectivity. PF-5006739 attenuats opioid agent-seeking behavior in a rodent operant reinstatement model in animals in a dose-dependent manner . PF-5006739 improves glucose tolerance in both diet-induced obesity (DIO) and genetic (ob/ob) mice models of obesity .
    PF-5006739
  • HY-149897
    HA-CD44 interaction inhibitor 2
    1 Publications Verification

    		 Transmembrane Glycoprotein CD44 Cancer
    HA-CD44 interaction inhibitor 2 is a CD44 inhibitor that can inhibit the interaction between Hyaluronic acid (HA) (HY-B0633A) and CD44. HA-CD44 interaction inhibitor 2 acts as an antiproliferative agent against CD44 + cancer cells. HA-CD44 interaction inhibitor 2 can disrupt the integrity of cancer spheres and reduce cancer cell viability in a dose-dependent manner. HA-CD44 interaction inhibitor 2 is applicable for tumor research .
    HA-CD44 interaction inhibitor 2
  • HY-10787
    Ximelagatran
    1 Publications Verification

    H 376/95

    		 Thrombin Cardiovascular Disease
    Ximelagatran (H 376/95) is an orally active thrombin inhibitor that selectively and competitively inhibits both free and clot-bound thrombin. Ximelagatran is an anticoagulant agent with a rapid onset of anticoagulant effect, predictable, dose-dependent pharmcokinetics and pharmacodynamics .
    Ximelagatran
  • HY-145964
    INE963

    		Parasite Haspin Kinase FLT3 Infection
    INE963 is a potent and fast-acting blood-stage antimalarial agent, with an EC50s of 3-6 nM. INE963 is potential for single-dose cures in uncomplicated malaria .
    INE963
  • HY-B1309
    Metacetamol

    AMAP

    		 Drug Derivative Mitochondrial Metabolism Infection Cancer
    Metacetamol (AMAP) is an analog of Acetaminophen (HY-66005). Metacetamol induces dose-dependent necrosis in primary hepatocytes via glutathione depletion, mitochondrial damage, and formation of mitochondrial protein adducts. Metacetamol derivatives act as anticancer and antibacterial agents. Metacetamol can be used in studies related to breast cancer, bacterial infections, and fungal infections (candidiasis) .
    Metacetamol
  • HY-W015307
    4-Ethyloctanoic acid

    		Drug Derivative Others
    4-Ethyloctanoic acid is a branched chain aliphatic carboxylic acid that can be found in blue cheeses, various cheese types, and lamb/mutton. 4-Ethyloctanoic acid is a fragrance ingredient .
    4-Ethyloctanoic acid
  • HY-B0094R
    Artemisinin (Standard)

    Qinghaosu (Standard); NSC 369397 (Standard)

    		 Reference Standards HCV Parasite Akt Ferroptosis Infection Neurological Disease Cancer
    Artemisinin (Standard) is the analytical standard of Artemisinin. This product is intended for research and analytical applications. Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants . Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects .
    Artemisinin (Standard)
  • HY-149906
    Trecovirsen

    GEM91

    		 HIV Infection
    Trecovirsen is an antiviral agent targeting HIV gag mRNA, which hybridizes with complementary HIV gag mRNA at the initiation site. Trecovirsen induces a reversible, dose-dependent prolongation of activated partial thromboplastin time via its polyanionic properties. Trecovirsen is applicable to research related to HIV infection .
    Trecovirsen
  • HY-117779
    DBIBB
    2 Publications Verification

    		 Apoptosis Endocrinology
    DBIBB is a specific nonlipid agonist of the type 2 G protein coupled receptor for lysophosphatidic acid (LPA2). DBIBB mitigates the gastrointestinal radiation syndrome, increases intestinal crypt survival and enterocyte proliferation, and reduces apoptosis. DBIBB represents a agent candidate capable of mitigating acute radiation syndrome caused by high-dose γ-radiation to the hematopoietic and gastrointestinal system .
    DBIBB
  • HY-123714
    TL4-12

    		MAP4K Apoptosis Inflammation/Immunology Cancer
    TL4-12 is a selective MAP4K2/GCK inhibitor, dose-dependently downregulates IKZF1 and BCL-6 and leads to MM cell proliferation inhibition (IC50=37 nM) accompanied by induction of apoptosis. TL4-12 can be used to overcome immunomodulatory agent resistance in multiple myeloma (MM) .
    TL4-12
  • HY-N1521
    Rehmannic acid

    Lantadene A

    		 Others Inflammation/Immunology
    Rehmannic acid (lantadene A) is a compound isolated from Lantana camara. Rehmannic acid shows considerable in vitro antioxidant, free radical scavenging capacity activities in a dose dependant manner. Rehmannic acid is a promising candidate for use as an antioxidant and hepatoprotective agent .
    Rehmannic acid
  • HY-N11911
    Verazine
    1 Publications Verification

    (-)-Verazine

    		 Fungal Infection Neurological Disease
    Verazine ((-)-Verazine) is an anti-Fungal Agent that can be found in the dried roots and rhizoma of Veratrum maackii Regel. Verazine causes DNA damage in the cerebellum and cerebral cortex of mice in a dose-dependent manner. Verazine can be used in the study of fungal infections and neurological diseases .
    Verazine
  • HY-N8481
    3,6-Dihydroxyflavone
    1 Publications Verification

    3,6-DHF

    		 Apoptosis Cancer
    3,6-Dihydroxyflavone is an anti-cancer agent. 3,6-Dihydroxyflavone dose- and time-dependently decreases cell viability and induces apoptosis by activating caspase cascade, cleaving poly (ADP-ribose) polymerase (PARP). 3,6-Dihydroxyflavone increases intracellular oxidative stress and lipid peroxidation .
    3,6-Dihydroxyflavone
  • HY-130323
    13-HPOT

    		Bacterial Infection
    13-HPOT is a linolenic acid hydroperoxide and an antibacterial agent. 13-HPOT interacts with lipid representatives of bacterial inner membranes. 13-HPOT exerts dose-dependent in vitro antibacterial activity against Pectobacterium carotovorum, Pseudomonas syringae pv. syringae DC3000, and Xanthomonas translucens pv. translucens .
    13-HPOT
  • HY-B0006S1
    Carvedilol-d4

    BM 14190-d4

    		 Adrenergic Receptor Autophagy Cardiovascular Disease Inflammation/Immunology Cancer
    Carvedilol-d4 is the deuterium labeled Carvedilol. Carvedilol (BM 14190) is a non-selective β/α-1 blocker . Carvedilol inhibits lipid peroxidation in a dose-dependent manner with an IC50 of 5 μM. Carvedilol is a multiple action antihypertensive agent with potential use in angina and congestive heart failure . Carvedilol is an autophagy inducer that inhibits the NLRP3 inflammasome .
    Carvedilol-d4
  • HY-B0006R
    Carvedilol (Standard)
    10+ Cited Publications

    BM 14190 (Standard)

    		 Reference Standards Adrenergic Receptor Autophagy Bacterial Cardiovascular Disease Inflammation/Immunology Cancer
    Carvedilol (Standard) is the analytical standard of Carvedilol. This product is intended for research and analytical applications. Carvedilol (BM 14190) is a non-selective β/α-1 blocker . Carvedilol inhibits lipid peroxidation in a dose-dependent manner with an IC50 of 5 μM. Carvedilol is a multiple action antihypertensive agent with potential use in angina and congestive heart failure . Carvedilol is an autophagy inducer that inhibits the NLRP3 inflammasome .
    Carvedilol (Standard)
  • HY-W728085
    CPPD-Q

    		Bacterial Antibiotic Insecticide Reactive Oxygen Species (ROS) Infection
    CPPD-Q is an antimicrobial agent and insecticide. CPPD-Q has an EC50 of 6.98 mg/L against Vibrio fischeri. At doses of 1 or 10 µg/mL, CPPD-Q exerts its insecticidal effect by inducing the production of reactive oxygen species (ROS) in the intestines of Caenorhabditis elegans .
    CPPD-Q
  • HY-123801
    MIDD0301

    GL-II-93

    		 GABA Receptor Inflammation/Immunology
    MIDD0301 (GL-II-93) is an orally available, active γ-aminobutyric acid type A receptor (GABAAR) inhibitor and anti-asthmatic agent. MIDD0301 exhibits biological and immunotoxicological safety in mice and does not affect the number of circulating lymphocytes, monocytes, and granulocytes. MIDD0301 has no significant adverse immune response at repeated doses, which is better than Prednisone (HY-B0214). MIDD0301 relaxes histamine-contracted guinea pig and human airway smooth muscle and is used in the study of bronchoconstrictive diseases .
    MIDD0301
  • HY-110241
    Dianicline dihydrochloride

    		nAChR Neurological Disease
    Dianicline dihydrochloride is a α4β2 nicotinic acetylcholine receptor partial agonist, a class of agents that includes varenicline and cytisine for smoking cessation. Dianicline dihydrochloride increases cessation rates in a dose-dependent manner .
    Dianicline dihydrochloride
  • HY-B0094S
    Artemisinin-d3

    Qinghaosu-d3; NSC 369397-d3

    		 Akt Ferroptosis HCV Parasite Infection Neurological Disease Cancer
    Artemisinin-d3 is the deuterium labeled Artemisinin. Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants . Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects .
    Artemisinin-d3
  • HY-W087892
    Barium diphenylamine-4-sulfonate

    		Biochemical Assay Reagents Others
    Barium diphenylamine-4-sulfonate can be employed as an intermediate in pharmaceutical manufacturing and in chemical research, and serves as a dosing agent in analytical testing .
    Barium diphenylamine-4-sulfonate
  • HY-146433
    Anticancer agent 55

    		Apoptosis Cancer
    Anticancer agent 55 is a potent anticancer agent. Anticancer agent 55 shows anticancer activity via reducing the cell viability and cell migration in a dose-dependent manner. Anticancer agent 55 induces apoptosis. Anticancer agent 55 has the potential for the research of prostate cancer and breast cancer .
    Anticancer agent 55
  • HY-151926
    Antiviral agent 24

    		Enterovirus Infection
    Antiviral agent 24 is a potent antiviral agent with EC50 values of 0.101, 19.9, 91.2 µM for EV71, CVA21, EV68, respectively. Antiviral agent 24 inhibits METTL3/METTL14 activity in a dose-dependent manner .
    Antiviral agent 24
  • HY-N0407R
    Picroside I (Standard)

    6'-Cinnamoylcatalpol (Standard)

    		 Reference Standards STAT Inflammation/Immunology
    Picroside I (Standard) is the analytical standard of Picroside I. This product is intended for research and analytical applications. Picroside I is the major ingredient of Picrorhiza scrophulariiflora. Picrorhiza scrophulariiflora is a high value medicinal herb due to rich source of hepatoprotective metabolites, Picroside-I and Picroside-II . Picroside I is a promising agent for the management of asthma. Picroside I reduces the inflammation significantly at its higher dose. Picroside I also downregulates pSTAT6 and GATA3 expressions. Picroside I dose-dependently increases the serum levels of IFN-γ .
    Picroside I (Standard)
  • HY-A0224
    Forasartan

    SC-52458

    		 Angiotensin Receptor Cardiovascular Disease
    Forasartan is an nonpeptide angiotensin AT1 receptor antagonist with an IC50 of 2.9 nM. Forasartan is also an anti-hypertension agent. Forasartan significantly inhibits preganglionic stimulation in a dose-dependent manner in vivo. Forasartan can inhibit the heart rate increase induced by angiotensin II .
    Forasartan
  • HY-127055
    Tiadenol

    		Apolipoprotein Metabolic Disease Endocrinology
    Tiadenol is an absorbable hypolipidemic agent. Tiadenol can effectively reduce triglycerides and decrease the level of apolipoprotein E in very low-density lipoproteins in hyperlipoproteinemia. Tiadenol causes hepatomegaly in rats and affects their hepatic lipid levels, cholesterol synthesis and absorption at high doses. Tiadenol can be used in the research of endocrine and metabolic diseases such as hyperlipidemia .
    Tiadenol
  • HY-165528
    Histamine glutarimide

    XC8

    		 CCR Inflammation/Immunology
    Histamine glutarimide (XC8) is an orally active anti-asthma agent. Histamine glutarimide blocks the maturation of chemokines (CCL2, CCL7, CCL8, CCL13) and inhibits the migration of eosinophils and the degranulation of mast cells. In asthma models induced by carrageenan and rat ovalbumin, Histamine glutarimide can reduce airway resistance and the count of eosinophils in bronchoalveolar lavage fluid. Histamine glutarimide can be used in asthma research .
    Histamine glutarimide
  • HY-12995A
    (S)-BI 665915

    		FLAP Inflammation/Immunology
    (S)-BI 665915 is an orally active oxadiazole-containing 5-lipoxygenase-activating protein (FLAP) inhibitor with an IC50 of 1.7 nM for FLAP binding. (S)-BI 665915 inhibits FLAP functional in human whole blood with an IC50 of 45 nM. (S)-BI 665915 demonstrates an excellent cross-species agent metabolism and pharmacokinetics (DMPK) profile and a dose-dependent inhibition of LTB4 production .
    (S)-BI 665915
  • HY-125916
    Pseurotin A

    		Endogenous Metabolite Cancer
    Pseurotin A is a secondary metabolite of Aspergillus and other fungi. Pseurotin A is a competitive inhibitor of chitin synthase and a neuritogenic agent. Pseurotin A inhibits IgE production (IC50 = 3.6 μM). Pseurotin A inhibits the PCSK9-LDLr interaction. Pseurotin A shows dose-dependent reduction of PCSK9, along with increased LDLR levels in hormone-dependent breast cancer cell lines. Pseurotin A exhibits antitumor activity .
    Pseurotin A
  • HY-145649A
    Zilebesiran sodium

    AD-85481 sodium; ALN-AGT sodium

    		 Small Interfering RNA (siRNA) Asialoglycoprotein Receptor (ASGPR) Cardiovascular Disease
    Zilebesiran (AD-85481; ALN-AGT) sodium is a long-acting liver-targeted small interfering RNA (siRNA) antihypertensive agent. Zilebesiran sodium binds to the hepatic asialoglycoprotein receptor (ASGPR), activates the RNA-induced silencing complex to degrade hepatic angiotensinogen mRNA, thereby inhibiting the gene expression and synthesis of angiotensinogen. Zilebesiran sodium dose-dependently reduces serum angiotensinogen levels and 24-hour ambulatory blood pressure, with its effect persisting throughout the circadian cycle. Zilebesiran sodium is applicable to research related to hypertension .
    Zilebesiran sodium
  • HY-136634
    BTM-1042

    		mAChR Others
    BTM-1042 is a newly synthesized compound with antispasmodic effects. It can inhibit the twitch reaction of the guinea pig ileum under electrical stimulation and is not affected by naloxone. It has similar effects to atropine and can block muscarinic receptors, but has less effect on other types of receptors. BTM-1042 also has an inhibitory effect on the ileal reaction caused by nicotine and 5-hydroxytryptamine. BTM-1042 showed a dose-dependent inhibitory effect on the spontaneous movement of the rabbit stomach. In general, BTM-1042 is a agent with a strong antispasmodic effect.
    BTM-1042
  • HY-146059
    Antibacterial agent 99

    		Bacterial Infection
    Antibacterial agent 99 (compound 7b) is a potent antibacterial agent. Antibacterial agent 99 shows significant antibacterial and antifungal activity. Antibacterial agent 99 dose not show haemolytic activity .
    Antibacterial agent 99
  • HY-155551
    Anti-inflammatory agent 46

    		NO Synthase Inflammation/Immunology
    Anti-inflammatory agent 46 (compound 7h) is an anti-inflammatory agent with nitric oxide (NO) inhibitory effect. Anti-inflammatory agent 46 binds to iNOS with low energies, inhibits swelling in mice (at dose of 10 mg/kg) .
    Anti-inflammatory agent 46
  • HY-106091B
    Losoxantrone hydrochloride

    CI 941 hydrochloride; DUP 94 hydrochloride

    		 DNA Alkylator/Crosslinker Cancer
    Losoxantrone hydrochloride (CI 941 hydrochloride) is a DNA-binding agent. Losoxantrone hydrochloride has broad-spectrum antitumour activity. Losoxantrone hydrochloride induces dose-dependent leukopenia .
    Losoxantrone hydrochloride
  • HY-161263
    Antibacterial agent 182

    		Bacterial Infection
    Antibacterial agent 182 (compound 8c) is an antibacterial agent that shows antibacterial activity against various Gram-positive bacteria, particularly against Vancomycin-resistant Enterococcus faecalis (MIC ≤0.125 μg/mL). Antibacterial agent 182 inhibits biofilm formation of Staphylococcus aureus and Pseudomonas aeruginosa at sub-MIC doses .
    Antibacterial agent 182
  • HY-146169
    Antitumor agent-68

    		Reactive Oxygen Species (ROS) Microtubule/Tubulin Cancer
    Antitumor agent-68 is a potent tubulin inhibitor. Antitumor agent-68 shows potent anticancer activity with IC50s of 3.6 and 3.8 μM for HeLa and MCF-7 cells, respectively. Antitumor agent-68 exhibits good scavenging activity of ROS and DPPH radical in a dose-dependent manner . Antitumor agent-68 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Antitumor agent-68
  • HY-114723
    NPD9948

    		DNA/RNA Synthesis Others
    NPD9948 is an antitussive agent with antitussive activity in a guinea pig antitussive test. Its half antitussive dose (AtD50) is 14.5 mg/kg and 22.6 mg/kg when injected intraperitoneally and orally, respectively.
    NPD9948

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: