Anti-osteoporosis agent-12
Anti-osteoporosis agent-12 (Compound 18) is an orally active pyrazole-fused betulinic acid derivative with potent anti-osteoporosis activity. Anti-osteoporosis agent-12 exhibits a strong inhibitory effect on RANKL-induced osteoclastogenesis in RAW264.7 cells, with an IC50 of 7.96 nM. Anti-osteoporosis agent-12 can dose-dependently improve key micro-CT parameters of bone, reduce the level of serum bone resorption marker (CTx), and effectively prevent ovariectomy-induced bone loss. Anti-osteoporosis agent can be used for the study of osteoporosis.
For research use only. We do not sell to patients.
- Formula: C45H73N3O7
- Molecular Weight:768.08
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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Molecular Weight 768.08
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Formula C45H73N3O7
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SMILES
CC([C@@H]1CC[C@]2(C(OCCCCCC(NCCOCCOCCOCCO)=O)=O)CC[C@@]3(C)[C@]4(C)CCC5C(C)(C)C6=NNC=C6C[C@]5(C)C4CCC3C21)=C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anti-osteoporosis agent-12 Related Classifications
HY-178355 Related Classifications
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