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Cat. No.: HY-N11911

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Verazine

Name: Verazine
Brand: MedChemExpress
SKU: HY-N11911
Price: 420.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: (-)-Verazine)

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

Verazine ((-)-Verazine) is an anti-Fungal Agent that can be found in the dried roots and rhizoma of Veratrum maackii Regel. Verazine causes DNA damage in the cerebellum and cerebral cortex of mice in a dose-dependent manner. Verazine can be used in the study of fungal infections and neurological diseases.

For research use only. We do not sell to patients.

Purity : 99.74%
CAS No.: 14320-81-1
Formula: C₂₇H₄₃NO
Molecular Weight:397.64

Storage:

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Verazine Chemical Structure

CAS No.: 14320-81-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Publications (1)
Protocols (1)
Purity & Documentation
References
Calculators
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Classifications
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Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
M109	IC₅₀	12.5 μg/mL Compound: 3, verazine	Cytotoxicity against mouse M109 cells Cytotoxicity against mouse M109 cells	[PMID: 9784152]

Chemical Information

CAS No. 14320-81-1
Appearance Solid
Molecular Weight 397.64
Formula C₂₇H₄₃NO
Color White to off-white
SMILES

C[C@]12[C@](CC[C@]1([H])[C@@H](C(CC3)=NC[C@H]3C)C)([H])[C@@](CC=C4C[C@H]5O)([H])[C@@](CC2)([H])[C@]4(CC5)C
Synonyms

(-)-Verazine
Structure Classification
- Alkaloids
- Other Alkaloids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Publications (1)

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ACS Synth Biol

Automated Strain Construction for Biosynthetic Pathway Screening in Yeast. [Abstract]

2025 Oct 17;14(10):4143-4151. PMID: 41063332

Protocols

All Animals and Diseases

Genotoxicity/Mutagenicity Study
The bacterial reverse mutation assay detects point mutations that restore amino-acid prototrophy in auxotrophic Salmonella typhimurium or Escherichia coli tester strains; after exposure to a test article, mutagenic activity is read out as an increased number of revertant colonies on minimal agar compared with the vehicle control. The assay uses tester strains with different mutation targets so that base-substitution and frameshift mutagens can be detected, and testing is performed with and without exogenous mammalian metabolic activation because some chemicals require biotransformation to become mutagenic.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Cong Y, et al. Steroidal Alkaloids from Veratrum maackii Regel with Genotoxicity on Brain-Cell DNA in Mice. Helv Chim Acta. 2015, 98(4): 539-545.

[2]. Augustin MM, et al. Elucidating steroid alkaloid biosynthesis in Veratrum californicum: production of verazine in Sf9 cells. Plant J. 2015 Jun;82(6):991-1003. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Verazine

Publications Citing Use of MedChemExpress (MCE) Verazine