14320-81-1
14320-81-1
Chemical Structure
Verazine
Synonym(s): (-)-Verazine
- CAS No.: 14320-81-1
- Formula:C27H43NO
- Molecular Weight:397.64
InChIKey: VRBNGKPRTHBEIQ-LURFOZDGSA-N
SMILES: C[C@]12[C@](CC[C@]1([H])[C@@H](C(CC3)=NC[C@H]3C)C)([H])[C@@](CC=C4C[C@H]5O)([H])[C@@](CC2)([H])[C@]4(CC5)C
Biological Activity: Verazine ((-)-Verazine) is an anti-Fungal Agent that can be found in the dried roots and rhizoma of Veratrum maackii Regel. Verazine causes DNA damage in the cerebellum and cerebral cortex of mice in a dose-dependent manner. Verazine can be used in the study of fungal infections and neurological diseases[1][2].
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Verazine | 99.74% | Verazine ((-)-Verazine) is an anti-Fungal Agent that can be found in the dried roots and rhizoma of Veratrum maackii Regel. Verazine causes DNA damage in the cerebellum and cerebral cortex of mice in a dose-dependent manner. Verazine can be used in the study of fungal infections and neurological diseases. | ||||||||||||||||||||
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References
- [1]. Cong Y, et al. Steroidal Alkaloids from Veratrum maackii Regel with Genotoxicity on Brain-Cell DNA in Mice. Helv Chim Acta. 2015, 98(4): 539-545.
- [2]. Augustin MM, et al. Elucidating steroid alkaloid biosynthesis in Veratrum californicum: production of verazine in Sf9 cells. Plant J. 2015 Jun;82(6):991-1003. [Content Brief]
Keywords
