Losoxantrone hydrochloride
Losoxantrone hydrochloride (CI 941 hydrochloride) is a DNA-binding agent. Losoxantrone hydrochloride has broad-spectrum antitumour activity. Losoxantrone hydrochloride induces dose-dependent leukopenia.
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- CAS. Nr.: 88303-61-1
- Formel: C22H29Cl2N5O4
- Molecular Weight:498.40
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| LoVo | IC50 |
0.053 μg/mL
Compound: DuP-941
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In vitro cytotoxicity on human colon adenocarcinoma (LoVo ) tumor cell line.
In vitro cytotoxicity on human colon adenocarcinoma (LoVo ) tumor cell line.
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[PMID: 9876113] |
| LoVo | IC50 |
44.5 μg/mL
Compound: DuP-941
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In vitro cytotoxicity on human colon adenocarcinoma resistant to doxorubicin (LoVo/Dx ) tumor cell line.
In vitro cytotoxicity on human colon adenocarcinoma resistant to doxorubicin (LoVo/Dx ) tumor cell line.
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[PMID: 9876113] |
Chemical Information
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CAS. Nr. 88303-61-1
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Molecular Weight 498.40
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Formel C22H29Cl2N5O4
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SMILES
OCCNCCNC1=C2C3=C(C=C1)N(CCNCCO)N=C3C4=C(C(O)=CC=C4)C2=O.Cl.Cl
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Synonyms
CI 941 hydrochloride; DUP 94 hydrochloride
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Losoxantrone hydrochloride Related Classifications
HY-106091B Related Classifications
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