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  4. WR 30090

WR 30090 (Compound 37) is a broad-spectrum antimalarial agent that does not rely on the classical antifolate pathway. WR 30090 exhibits strong activity against a variety of chloroquine-sensitive and resistant Plasmodium falciparum strains, especially the highly resistant Vietnamese strain. WR 30090 shows high activity in mouse malaria tests, with a minimum effective dose of 5 mg/kg and a minimum cure dose of 20 mg/kg. WR 30090 can be used for research on acute malaria.

For research use only. We do not sell to patients.

WR 30090

WR 30090 Chemical Structure

CAS No. : 19160-62-4

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WR 30090 Related Antibodies

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Description

WR 30090 (Compound 37) is a broad-spectrum antimalarial agent that does not rely on the classical antifolate pathway. WR 30090 exhibits strong activity against a variety of chloroquine-sensitive and resistant Plasmodium falciparum strains, especially the highly resistant Vietnamese strain. WR 30090 shows high activity in mouse malaria tests, with a minimum effective dose of 5 mg/kg and a minimum cure dose of 20 mg/kg. WR 30090 can be used for research on acute malaria[3][4][5].

Molecular Weight

514.31

Formula

C25H28Cl4N2O
CAS No.
SMILES

ClC=1C=C(Cl)C2=NC(=CC(=C2C1)C(O)CN(CCCC)CCCC)C=3C=CC(Cl)=C(Cl)C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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WR 30090 Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WR 3009019160-62-4WR30090WR-30090Parasitequinoline methanolantimalarialPlasmodium falciparumPlasmodium vivaxchloroquine resistanceclinical trialphotosensitivitydrug toleranceradical cureInhibitorinhibitorinhibit

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