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Results for "

growth-hormone

" in MedChemExpress (MCE) Product Catalog:

By Targets:	GHR (19) GHSR (43) 5-HT Receptor (1) Adenylate Cyclase (2) Adrenergic Receptor (1) Akt (1) Amine N-methyltransferase (1) Amino Acid Derivatives (3) Apoptosis (2) Autophagy (9) Bacterial (1) Biochemical Assay Reagents (5) Cholinesterase (ChE) (1) CRFR (1) Cytochrome P450 (2) Dopamine Receptor (1) Drug Derivative (1) Drug Intermediate (1) Drug Metabolite (10) Endogenous Metabolite (23) Environmental Pollutants (2) Estrogen Receptor/ERR (2) GCGR (1) GnRH Receptor (2) Herbicide (1) IFNAR (1) IGF-1R (5) Insecticide (2) Insulin Receptor (2) Interleukin Related (1) Isotope-Labeled Compounds (14) Kisspeptin Receptor (1) Molecular Glues (1) Phytohormone (1) Reference Standards (7) Small Interfering RNA (siRNA) (2) Somatostatin Receptor (8) STAT (2) TNF Receptor (1)
By Research Areas:	Cancer (21) Cardiovascular Disease (8) Endocrinology (43) Infection (3) Inflammation/Immunology (9) Metabolic Disease (38) Neurological Disease (22)
Oligonucleotides:	Antisense Oligonucleotides (4)

128

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Targets Recommended: GHR GHSR

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-17365

Octreotide acetate Maximum Cited Publications 16 Publications Verification SMS 201-995 acetate	Somatostatin Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits *growth hormone, glucagon, and insulin* more potently.

HY-N0384

Homovanillic acid Vanilacetic acid	Drug Metabolite Endogenous Metabolite Autophagy	Metabolic Disease
Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-50844

Ibutamoren Mesylate 5 Publications Verification MK-677; MK-0677	GHSR	Endocrinology
Ibutamoren Mesylate (MK-677) is a potent, non-peptide Growth hormone secretagogue receptor (GHSR) agonist. Ibutamoren Mesylate is an orally active growth hormone (GH) secretagogue.

HY-N0848

Epibrassinolide 15+ Cited Publications 24-Epibrassinolide; B1105; BP55	Environmental Pollutants Apoptosis	Cancer
Epibrassinolide (24-Epibrassinolide) is a ubiquitously occurring plant growth hormone which shows great potential to alleviate heavy metals and pesticide stress in plants . Epibrassinolide is a potential apoptotic inducer in various cancer cells without affecting the non-tumor cell growth .

HY-14734

Anamorelin 5+ Cited Publications RC-1291; ONO-7643	GHSR	Endocrinology Cancer
Anamorelin (RC-1291) is an orally active Ghrelin receptor agonist with an EC₅₀ of 0.74 nM. Anamorelin can promote appetite, increase body weight, and stimulate the secretion of growth hormone and insulin-like growth factor-1. Anamorelin can be used in the research of anorexia and cancer cachexia .

HY-B1161

Methoprene 10+ Cited Publications ZR-515	Environmental Pollutants Insecticide	Others
Methoprene, an insect juvenile growth hormone mimic, is a growth-regulating insecticide that manifests its toxicity to target organisms by acting as a juvenile hormone agonist .

HY-14820A

Macimorelin acetate EP-1572 acetate; AEZS-130 acetate	GHSR	Neurological Disease Endocrinology Cancer
Macimorelin (EP-1572) acetate, a GH secretagogue, is an orally active GHSR agonist. Macimorelin acetate stimulates GH release. Macimorelin acetate can be used in the research of adult growth hormone deficiency (AGHD), and Cancer anorexia-cachexia syndrome (CACS) .

HY-14734A

Anamorelin hydrochloride 5+ Cited Publications RC-1291 hydrochloride; ONO-7643 hydrochloride	GHSR	Endocrinology Cancer
Anamorelin (RC-1291) hydrochloride is an orally active Ghrelin receptor agonist with an EC₅₀ of 0.74 nM. Anamorelin hydrochloride can promote appetite, increase body weight, and stimulate the secretion of growth hormone and insulin-like growth factor-1. Anamorelin hydrochloride can be used in the research of anorexia and cancer cachexia .

HY-15243

Capromorelin Tartrate CP 424391-18	GHSR	Neurological Disease Endocrinology
Capromorelin Tartrate is an orally active, potent growth hormone secretagogue receptor (GHSR) agonist, with K_i of 7 nM for hGHS-R1a.

HY-10199A

Ibutamoren 5 Publications Verification MK-677 free base; MK-0677 free base	GHSR Insulin Receptor	Neurological Disease Metabolic Disease
Ibutamoren (MK-677 free base; MK-0677 free base) is an orally active non-peptide growth hormone secretagogue receptor agonist. Ibutamoren activates signal cascades by mimicking endogenous ligands, triggers pulsatile release of growth hormone from the pituitary gland, and increases serum levels of IGF-1 and *insulin-like growth* factor-binding protein 3*. Ibutamoren not only increases the frequency of growth hormone* pulses in male individuals, but also promotes elevated bone formation markers in female individuals with postmenopausal osteoporosis. The combination of Ibutamoren with Alendronate sodium hydrate (HY-11101) significantly increases bone mineral density at the femoral neck. However, Ibutamoren may cause mild, reversible adverse reactions such as increased appetite, fluid retention, and elevated fasting blood glucose. Ibutamoren has been widely used in studies related to idiopathic growth hormone deficiency, sarcopenia, Alzheimer's disease, and osteoporosis .

HY-19884B

Relamorelin TFA 1 Publications Verification RM-131 TFA; BIM-28131 TFA	GHSR	Metabolic Disease
Relamorelin (RM-131) TFA, a pentapeptide ghrelin analog, is a selective *ghrelin/growth hormone* secretagogue receptor (GHSR) agonist with a K_i of 0.42 nM for GHS-1a** receptor. Relamorelin TFA is centrally penetrant. Relamorelin TFA increases growth hormone levels and accelerates gastric emptying. Relamorelin TFA has the potential for cachexia, gastroparesis, and gastric/intestinal dysmobility disorders research .

HY-W016784

Indole-3-acetamide 2 Publications Verification	Endogenous Metabolite	Others
Indole-3-acetamide is a biosynthesis intermediate of 3-Indoleacetic acid (HY-18569). Indole-3-acetic acid is the most common natural plant growth hormone of the auxin class .

HY-108905

Mecasermin Human IGF-I; FK 780	IGF-1R	Metabolic Disease
Mecasermin (Human IGF-I; FK 780) is a recombinant human insulin-like growth factor I (IGF-I). Mecasermin has the potential for the study of the growth failure of growth hormone (GH) insensitivity caused by GH receptor defects or GH-inhibiting antibodies .

HY-18570B

1-Naphthaleneacetic acid,suitable for plant cell culture NAA	Biochemical Assay Reagents	Others
1-Naphthaleneacetic acid,suitable for plant cell culture (NAA) is a plant growth hormone. 1-Naphthaleneacetic acid,suitable for plant cell culture promotes plant growth and induces root cluster formation. Naphthaleneacetic acid,suitable for plant cell culture is applicable for plant cell culture .

HY-P3582

sGnRH-A	GnRH Receptor	Endocrinology
sGnRH-A is a salmon gonadotropin-releasing hormone (GnRH) analogue. sGnRH-A stimulates growth hormone secretion. sGnRH-A also can be used as an inducer of ovulation by artificial insemination .

HY-P3304

MR 409	GHR	Neurological Disease Cancer
MR 409 is a selected growth hormone-releasing hormone (GHRH) agonist. MR 409 has remarkable neuroprotective effects through enhancing endogenous neurogenesis in cerebral ischemic mice. MR 409 also inhibits the in vivo growth of lung cancer .

HY-P1155

GRF (1-29) amide (rat) 1 Publications Verification rGHRH(1-29)NH2	GHSR	Cancer
GRF (1-29) amide (rat) is a synthetic peptide which can stimulate the *growth hormone* (GH) secretion.

HY-U00433

JMV 2959 3 Publications Verification	GHSR	Neurological Disease Endocrinology
JMV 2959 is a growth hormone secretagogue receptor type 1a (GHS-R_1a) antagonist with an IC₅₀ of 32 nM.

HY-113906A

(αR,8aS)-GSK1614343	GHSR	Metabolic Disease
(αR,8aS)-GSK1614343 is the isomer of GSK1614343 (HY-113906). GSK1614343 is the potent antagonist of growth hormone secretagogues type 1a (GHS1a) receptors .

HY-18569S3

3-Indoleacetic acid-d7 Indole-3-acetic acid-d₇; 3-IAA-d₇	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
3-Indoleacetic acid-d₇ is the deuterium labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division .

HY-18569S4

3-Indoleacetic acid-13C6 Indole-3-acetic acid-¹³C₆; 3-IAA-¹³C₆	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
3-Indoleacetic acid- ¹³C₆ is the ¹³C labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division .

HY-P0089A

*Human growth hormone-releasing factor TFA* growth hormone Releasing Factor human TFA; Somatorelin (1-44) amide (human) TFA	GHR	Endocrinology
Human growth hormone-releasing factor TFA (Growth Hormone Releasing Factor human TFA) is a hypothalamic polypeptide and stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary .

HY-P5189A

His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA	Endogenous Metabolite Cholinesterase (ChE)	Others
His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA, is a growth hormone releasing peptide, as well as a metabolite of GHRP-1. GHRP-1, or Ala-His-D-beta Nal-Ala-Trp-D-Phe-Lys-NH2, has the effect of promoting the release of growth hormone (GH). GHRP-1 increases GH release and increases [Ca2+]i levels in static monolayer cells of rat pituitary gland, but does not affect cAMP levels .

HY-P1366

des-Gln14-Ghrelin 1 Publications Verification	GHSR	Metabolic Disease
des-Gln14-Ghrelin is a second endogenous ligand for the growth hormone secretagogue receptor. a). des-Gln14-ghrelin potently induces increases in [Ca ²⁺]i in CHO-GHSR62 cells, with an EC₅₀ of 2.4 nM .

HY-131514

L-Ornithine 2-oxoglutarate Ornithine α-ketoglutarate; OKG	Insulin Receptor GHR	Inflammation/Immunology
L-Ornithine 2-oxoglutarate (Ornithine alpha-ketoglutarate) is a nutritional compound that is a salt of amino acids with antioxidant and anti-inflammatory effects. L-Ornithine 2-oxoglutarate stimulates the production of insulin and growth hormone, and promotes intracellular amino acid transport and protein synthesis .

HY-N0384S2

Homovanillic acid-d5 Vanilacetic acid-d₅	Isotope-Labeled Compounds Autophagy Endogenous Metabolite Drug Metabolite	Neurological Disease Metabolic Disease
Homovanillic acid-d₅ (Vanilacetic acid-d₅) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-P11341

Kisspeptin antagonist p271	Kisspeptin Receptor	Endocrinology
Kisspeptin antagonist p271 is a Kisspeptin antagonist with cell-penetrating ability. Kisspeptin antagonist p271 can block the binding of endogenous Kisspeptin to GPR54 on pituitary somatotropes, thereby relieving the inhibition of growth hormone secretion. Kisspeptin antagonist p271 can specifically and significantly stimulate growth hormone secretion, while inhibiting luteinizing hormone without affecting prolactin or cortisol. Kisspeptin antagonist p271 can be used in the research of diseases related to insufficient growth hormone secretion .

HY-P1547

Somatostatin-25	GHSR	Neurological Disease
Somatostatin-25 is a endogenous neuropeptide hormone that shows inhibitory activity against secretion of growth hormone.

HY-P99924

Efpegsomatropin	GHR	Others
Efpegsomatropin is a long-acting human growth hormone-Fc conjugate. Efpegsomatropin is applicable for biochemical research .

HY-164419A

Atesidorsen sodium COR-004 sodium; ATL1103 sodium; ISIS 227452 sodium	GHR	Others
Atesidorsen sodium is a second-generation, antisense oligomer designed to inhibit translation of human growth hormone receptor (GHR) mRNA

HY-N12348

Emoghrelin	GHSR	Others
Emoghrelin, isolated from? Heshouwu Polygonum multiflorum, stimulates growth hormone secretion via activation of the ghrelin receptor .

HY-U00433A

JMV 2959 hydrochloride 3 Publications Verification	GHSR	Neurological Disease Endocrinology
JMV 2959 hydrochloride is a growth hormone secretagogue receptor type 1a (GHS-R_1a) antagonist with an IC₅₀ of 32±3 nM in LLC-PK₁ cells.

HY-50760

L-692585	GHSR	Endocrinology
L-692585 is a potent and nonpeptidyl growth hormone secretagogue receptor (GHS-R1a) agonist, with a K_i of 0.8 nM. L-692585 acts directly on somatotropes causing GH release .

HY-P10283

S1H	GHSR STAT	Endocrinology
S1H, a mimetic of hGH, is a *human growth hormone* receptor (hGHR)** antagonist. S1H inhibits the interaction of hGH with hGHR. S1H inhibits phosphorylation of STAT5 in cells co-treated with hGH .

HY-N0384R

Homovanillic acid (Standard) Vanilacetic acid (Standard)	Reference Standards Autophagy Endogenous Metabolite Drug Metabolite	Neurological Disease Metabolic Disease
Homovanillic acid (Standard) (Vanilacetic acid (Standard)) is the analytical standard of Homovanillic acid (HY-N0384). This product is intended for research and analytical applications. Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-W008024

Fmoc-Dab(Boc)-OH	Amino Acid Derivatives	Others
Fmoc-Dab(Boc)-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize somatostatin analogs that inhibit neointima formation induced by balloon injury in rats without altering growth hormone release. Fmoc-Dab(Boc)-OH can be used for the synthesis of peptides .

HY-P3397A

JV-1-36 acetate	GHR	Cancer
JV-1-36 acetate is a growth hormone-releasing hormone (GHRH) antagonist. JV-1-36 acetate inhibits the production of reactive oxygen species in A549 lung cancer cells. JV-1-36 can be used to study the effect of GHRH antagonists in vitro .

HY-P3596A

GHRF, mouse TFA Mouse growth hormone-releasing factor TFA	GHSR	Endocrinology
GHRF, mouse TFA, a mouse growth hormone-releasing factor, is a peptide containing 44 amino acids. GHRF, mouse TFA stimulates the release and synthesis of growth hormone .

HY-153485

Cimdelirsen ISIS 766720; IONIS-GHR-LRx	GHR Small Interfering RNA (siRNA)	Others
Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients.

HY-121580

Tabimorelin NN703	Cytochrome P450	Endocrinology
Tabimorelin (NN703) is an orally active *growth hormone* (GH) secretagogue. Tabimorelin is also a potent inhibitor of CYP3A4 activity .

HY-176258S

Growth Hormone 22, Arg-13C6,15N4, Lys-13C6,15N2	Isotope-Labeled Compounds	Metabolic Disease

HY-N0384S

Homovanillic acid-d3 Vanilacetic acid-d₃	Isotope-Labeled Compounds Autophagy Endogenous Metabolite Drug Metabolite	Neurological Disease Metabolic Disease
Homovanillic acid-d₃ (Vanilacetic acid-d₃) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-P0024A

Veldoreotide TFA DG3173 TFA; PTR-3173 TFA	Somatostatin Receptor	Endocrinology Cancer
Veldoreotide (DG3173) TFA a somatostatin analogue, binds to and activate the somatostatin receptors (SSTR) 2, 4, and 5. Veldoreotide TFA inhibits growth hormone (GH) secretion in adenomas compared with Octreotide (HY-P0036). Veldoreotide has the potential to be used as pain modulating agent

HY-106103A

Seglitide acetate MK 678 acetate; L 36358 acetate	Somatostatin Receptor	Cardiovascular Disease Neurological Disease Metabolic Disease
Seglitide acetate (MK 678; L 36358 acetate) is a potent, orally active somatostatin receptor 2 (SSTR₂) agonist, and also a competitive antagonist of SSTR₁₄, SSTR₂₅, and SSTR₂₈. Seglitide acetate has antihypertensive effects and can inhibit plasma glucagon and growth hormone. Seglitide acetate can be used for research on diabetes .

HY-P0089

*Human growth hormone-releasing factor* growth hormone Releasing Factor human; Somatorelin (1-44) amide (human)	GHR	Endocrinology
Human growth hormone-releasing factor (Growth Hormone Releasing Factor human) is a hypothalamic polypeptide and stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary .

HY-P3596

GHRF, mouse Mouse growth hormone-releasing factor	GHSR	Endocrinology
GHRF, mouse, a mouse growth hormone-releasing factor, is a peptide containing 44 amino acids. GHRF, mouse stimulates the release and synthesis of growth hormone .

HY-P10964

Tezusomant	GHSR	Endocrinology
Tezusomant is a growth hormone receptor antagonist. Tezusomant is promising for research on diseases caused by excessive growth hormone secretion, such as acromegaly .

HY-P3595

GHRF, porcine	GHR	Endocrinology
GHRF, porcine is a growth hormone releasing factor (GHRF) peptide (porcine). GHRF binds to GHSR and induces the release of growth hormone .

HY-153485A

Cimdelirsen sodium ISIS 766720 sodium; IONIS-GHR-LRx sodium	GHR Small Interfering RNA (siRNA)	Others
Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients.

HY-19884

Relamorelin RM-131; BIM-28131	GHSR	Metabolic Disease
Relamorelin (RM-131), a pentapeptide ghrelin analog, is a selective *ghrelin/growth hormone* secretagogue receptor (GHSR) agonist with a K_i of 0.42 nM for GHS-1a** receptor. Relamorelin is centrally penetrant. Relamorelin increases growth hormone levels and accelerates gastric emptying. Relamorelin has the potential for cachexia, gastroparesis, and gastric/intestinal dysmobility disorders research .

Cat. No.	Product Name

HY-L211

Human Hormone Compound Library

87 compounds

Hormones are a class of biologically active substances secreted by endocrine gland cells, which are transported through the circulatory system to various parts of the body, and precisely act on specific target organs or cells, playing a crucial role in regulating the growth, development, metabolism, and reproduction of organisms. The mechanisms of hormone action are diverse and complex. Some hormones (such as corticosteroids, vitamin D, and thyroid hormones) can enter the cell interior and interact with receptors in the nucleus, thereby regulating gene expression and affecting cell function. Other hormones (such as growth hormone and thyrotropin-releasing hormone) bind directly to receptors on the cell surface, exerting their effects by regulating enzyme activity or influencing the state of ion channels. Additionally, hormones play a key role in the study of endocrine and metabolic diseases, and are closely related to the development of diseases such as diabetes and thyroid diseases.

MCE has included 87 human hormone compounds, which is of great significance for the study of human metabolic pathways, and can also be used to build a metabonomics database.

Cat. No.	Product Name	Type

HY-18569B

3-Indoleacetic acid,suitable for plant cell culture

1 Publications Verification

IAA

Biochemical Assay Reagents

3-Indoleacetic acid, suitable for plant cell culture (IAA), is a naturally occurring plant growth hormone that is widely present in plants, bacteria, and fungi. 3-Indoleacetic acid, suitable for plant cell culture, is a plant growth-promoting hormone that not only promotes plant growth but also protects bacteria from the toxic damage to cell membrane potential caused by other indole intermediate products (such as I3P) produced during their own metabolic processes. 3-Indoleacetic acid, suitable for plant cell culture, can be used in plant cell culture .

HY-18570B

1-Naphthaleneacetic acid,suitable for plant cell culture NAA	Biochemical Assay Reagents
1-Naphthaleneacetic acid,suitable for plant cell culture (NAA) is a plant growth hormone. 1-Naphthaleneacetic acid,suitable for plant cell culture promotes plant growth and induces root cluster formation. Naphthaleneacetic acid,suitable for plant cell culture is applicable for plant cell culture .

HY-179179

1/2 MS Medium	Biochemical Assay Reagents
1/2 MS Medium has a similar composition to standard MS medium, including inorganic salts, sucrose, vitamins, etc. Unlike MS medium, 1/2 MS Medium contains a lower concentration of plant growth hormones (such as indoleacetic acid and adenosine), typically half the concentration of standard MS medium.

HY-179179A

1/2 MS Medium (Agar-Free, Sucrose-Free)	Biochemical Assay Reagents
1/2 MS Medium (Agar-Free, Sucrose-Free) has a similar composition to standard MS medium, including inorganic salts, sucrose, vitamins, etc. Unlike MS medium, 1/2 MS Medium (Agar-Free, Sucrose-Free) contains a lower concentration of plant growth hormones (such as indoleacetic acid and adenosine), typically half the concentration of standard MS medium.

HY-182659

3/4 MS Medium (Agar-Free, Sucrose-Free)	Biochemical Assay Reagents
3/4 MS Medium (Agar-Free, Sucrose-Free) has a similar composition to standard MS medium, including inorganic salts, sucrose, and vitamins. However, unlike standard MS medium, 3/4 MS Medium (Agar-Free, Sucrose-Free) contains lower concentrations of plant growth hormones (such as indoleacetic acid and adenosine), typically three-quarters the concentration found in standard MS medium.

Cat. No.	Product Name	Target	Research Area

HY-17365

Octreotide acetate Maximum Cited Publications 16 Publications Verification SMS 201-995 acetate	Somatostatin Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits *growth hormone, glucagon, and insulin* more potently.

HY-P0084

Cyclic somatostatin SRIF-14; Somatostatin-14	Endogenous Metabolite	Cardiovascular Disease Neurological Disease
Cyclic somatostatin (SRIF-14) is a growth hormone-release inhibiting factor used in the research of severe, acute hemorrhages of gastroduodenal ulcers. Cyclic somatostatin is a neuropeptide co-stored with acetylcholine in the cardiac parasympathetic innervation, exerts influences directly on contraction of ventricular cardiomyocytes. Cyclic somatostatin inhibits the contractile response of isoprenaline with an IC₅₀ value of 13 nM. Cyclic somatostatin can be used for the research of cardiovascular disease .

HY-19884B

Relamorelin TFA 1 Publications Verification RM-131 TFA; BIM-28131 TFA	GHSR	Metabolic Disease
Relamorelin (RM-131) TFA, a pentapeptide ghrelin analog, is a selective *ghrelin/growth hormone* secretagogue receptor (GHSR) agonist with a K_i of 0.42 nM for GHS-1a** receptor. Relamorelin TFA is centrally penetrant. Relamorelin TFA increases growth hormone levels and accelerates gastric emptying. Relamorelin TFA has the potential for cachexia, gastroparesis, and gastric/intestinal dysmobility disorders research .

HY-108905

Mecasermin Human IGF-I; FK 780	IGF-1R	Metabolic Disease
Mecasermin (Human IGF-I; FK 780) is a recombinant human insulin-like growth factor I (IGF-I). Mecasermin has the potential for the study of the growth failure of growth hormone (GH) insensitivity caused by GH receptor defects or GH-inhibiting antibodies .

HY-P3582

sGnRH-A	GnRH Receptor	Endocrinology
sGnRH-A is a salmon gonadotropin-releasing hormone (GnRH) analogue. sGnRH-A stimulates growth hormone secretion. sGnRH-A also can be used as an inducer of ovulation by artificial insemination .

HY-P3304

MR 409	GHR	Neurological Disease Cancer
MR 409 is a selected growth hormone-releasing hormone (GHRH) agonist. MR 409 has remarkable neuroprotective effects through enhancing endogenous neurogenesis in cerebral ischemic mice. MR 409 also inhibits the in vivo growth of lung cancer .

HY-P5645

LEAP-2 1 Publications Verification Human liver expressed antimicrobial peptide-2	GHSR Interleukin Related IFNAR TNF Receptor Bacterial	Infection Metabolic Disease Inflammation/Immunology
LEAP-2 (Human liver expressed antimicrobial peptide-2) is a GHS-R1a antagonist, with an IC₅₀ of 6.0 nM. LEAP-2 suppresses the orexigenic effect of ghrelin. LEAP-2 attenuates ghrelin-induced growth hormone (GH) release and reduces basal food intake. LEAP-2 exhibits antimicrobial activity against microbial model organisms. LEAP-2 can be used for the study of obesity and infection .

HY-P1155

GRF (1-29) amide (rat) 1 Publications Verification rGHRH(1-29)NH2	GHSR	Cancer
GRF (1-29) amide (rat) is a synthetic peptide which can stimulate the *growth hormone* (GH) secretion.

HY-P1777

IGF-I (24-41) Insulin-like growth Factor I (24-41)	IGF-1R	Metabolic Disease Inflammation/Immunology
IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) is amino acids 24 to 41 fragment of IGF-I. IGF-I, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I is partly responsible for systemic growth hormone (GH) activities. IGF-I has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) regulates somatic growth and behavioral development .

HY-P0089A

*Human growth hormone-releasing factor TFA* growth hormone Releasing Factor human TFA; Somatorelin (1-44) amide (human) TFA	GHR	Endocrinology
Human growth hormone-releasing factor TFA (Growth Hormone Releasing Factor human TFA) is a hypothalamic polypeptide and stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary .

HY-P5189A

His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA	Endogenous Metabolite Cholinesterase (ChE)	Others
His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA, is a growth hormone releasing peptide, as well as a metabolite of GHRP-1. GHRP-1, or Ala-His-D-beta Nal-Ala-Trp-D-Phe-Lys-NH2, has the effect of promoting the release of growth hormone (GH). GHRP-1 increases GH release and increases [Ca2+]i levels in static monolayer cells of rat pituitary gland, but does not affect cAMP levels .

HY-P1366

des-Gln14-Ghrelin 1 Publications Verification	GHSR	Metabolic Disease
des-Gln14-Ghrelin is a second endogenous ligand for the growth hormone secretagogue receptor. a). des-Gln14-ghrelin potently induces increases in [Ca ²⁺]i in CHO-GHSR62 cells, with an EC₅₀ of 2.4 nM .

HY-P11341

Kisspeptin antagonist p271	Kisspeptin Receptor	Endocrinology
Kisspeptin antagonist p271 is a Kisspeptin antagonist with cell-penetrating ability. Kisspeptin antagonist p271 can block the binding of endogenous Kisspeptin to GPR54 on pituitary somatotropes, thereby relieving the inhibition of growth hormone secretion. Kisspeptin antagonist p271 can specifically and significantly stimulate growth hormone secretion, while inhibiting luteinizing hormone without affecting prolactin or cortisol. Kisspeptin antagonist p271 can be used in the research of diseases related to insufficient growth hormone secretion .

HY-P1547

Somatostatin-25	GHSR	Neurological Disease
Somatostatin-25 is a endogenous neuropeptide hormone that shows inhibitory activity against secretion of growth hormone.

HY-P10283

S1H	GHSR STAT	Endocrinology
S1H, a mimetic of hGH, is a *human growth hormone* receptor (hGHR)** antagonist. S1H inhibits the interaction of hGH with hGHR. S1H inhibits phosphorylation of STAT5 in cells co-treated with hGH .

HY-W008024

Fmoc-Dab(Boc)-OH	Amino Acid Derivatives	Others
Fmoc-Dab(Boc)-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize somatostatin analogs that inhibit neointima formation induced by balloon injury in rats without altering growth hormone release. Fmoc-Dab(Boc)-OH can be used for the synthesis of peptides .

HY-P3397A

JV-1-36 acetate	GHR	Cancer
JV-1-36 acetate is a growth hormone-releasing hormone (GHRH) antagonist. JV-1-36 acetate inhibits the production of reactive oxygen species in A549 lung cancer cells. JV-1-36 can be used to study the effect of GHRH antagonists in vitro .

HY-P3596A

GHRF, mouse TFA Mouse growth hormone-releasing factor TFA	GHSR	Endocrinology
GHRF, mouse TFA, a mouse growth hormone-releasing factor, is a peptide containing 44 amino acids. GHRF, mouse TFA stimulates the release and synthesis of growth hormone .

HY-P0024A

Veldoreotide TFA DG3173 TFA; PTR-3173 TFA	Somatostatin Receptor	Endocrinology Cancer
Veldoreotide (DG3173) TFA a somatostatin analogue, binds to and activate the somatostatin receptors (SSTR) 2, 4, and 5. Veldoreotide TFA inhibits growth hormone (GH) secretion in adenomas compared with Octreotide (HY-P0036). Veldoreotide has the potential to be used as pain modulating agent

HY-106103A

Seglitide acetate MK 678 acetate; L 36358 acetate	Somatostatin Receptor	Cardiovascular Disease Neurological Disease Metabolic Disease
Seglitide acetate (MK 678; L 36358 acetate) is a potent, orally active somatostatin receptor 2 (SSTR₂) agonist, and also a competitive antagonist of SSTR₁₄, SSTR₂₅, and SSTR₂₈. Seglitide acetate has antihypertensive effects and can inhibit plasma glucagon and growth hormone. Seglitide acetate can be used for research on diabetes .

HY-P0089

*Human growth hormone-releasing factor* growth hormone Releasing Factor human; Somatorelin (1-44) amide (human)	GHR	Endocrinology
Human growth hormone-releasing factor (Growth Hormone Releasing Factor human) is a hypothalamic polypeptide and stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary .

HY-P3596

GHRF, mouse Mouse growth hormone-releasing factor	GHSR	Endocrinology
GHRF, mouse, a mouse growth hormone-releasing factor, is a peptide containing 44 amino acids. GHRF, mouse stimulates the release and synthesis of growth hormone .

HY-P10964

Tezusomant	GHSR	Endocrinology
Tezusomant is a growth hormone receptor antagonist. Tezusomant is promising for research on diseases caused by excessive growth hormone secretion, such as acromegaly .

HY-P3595

GHRF, porcine	GHR	Endocrinology
GHRF, porcine is a growth hormone releasing factor (GHRF) peptide (porcine). GHRF binds to GHSR and induces the release of growth hormone .

HY-19884

Relamorelin RM-131; BIM-28131	GHSR	Metabolic Disease
Relamorelin (RM-131), a pentapeptide ghrelin analog, is a selective *ghrelin/growth hormone* secretagogue receptor (GHSR) agonist with a K_i of 0.42 nM for GHS-1a** receptor. Relamorelin is centrally penetrant. Relamorelin increases growth hormone levels and accelerates gastric emptying. Relamorelin has the potential for cachexia, gastroparesis, and gastric/intestinal dysmobility disorders research .

HY-P3582A

sGnRH-A acetate	GnRH Receptor	Endocrinology
sGnRH-A acetate is a salmon gonadotropin-releasing hormone (GnRH) analogue. sGnRH-A acetate stimulates growth hormone secretion. sGnRH-A acetate also can be used as an inducer of ovulation by artificial insemination .

HY-P3169

a-Helical Corticotropin Releasing Factor (9-41)	CRFR	Inflammation/Immunology
α-Helical Corticotropin Releasing Factor (9-41) is a corticotropin releasing factor (CRF) antagonist. α-Helical Corticotropin Releasing Factor (9-41) decreases plasma growth hormone (GH) values in vivo .

HY-P4657

*Human Growth Hormone* (1-43)**	Peptides	Endocrinology
Human Growth Hormone (1-43) is an N-terminal fragment of human growth hormone with specific and pronounced insulin-like activity. Human Growth Hormone (1-43) can be used to study the function and metabolic pathways of growth hormone, a potential obesity-related factor .

HY-P0024

Veldoreotide DG3173; PTR-3173	Somatostatin Receptor	Endocrinology Cancer
Veldoreotide (DG3173) a somatostatin analogue, binds to and activate the somatostatin receptors (SSTR) 2, 4, and 5. Veldoreotide inhibits growth hormone (GH) secretion in adenomas compared withOctreotide (HY-P0036). Veldoreotide has the potential to be used as pain modulating agent

HY-P3594

[His1,Nle27] GHRF (1-32), amide, human	GHR	Endocrinology
[His1,Nle27] GHRF (1-32), amide, human is a Growth hormone releasing hormone (GHRH) analog. [His1,Nle27] GHRF (1-32), amide, human has great receptor affinity for GHRHR .

HY-P11153

HGH fragment 176-191	Estrogen Receptor/ERR	Cancer
HGH fragment 176-191 is a fragment of Human Growth Hormone. HGH fragment 176-191 binds with high affinity to Ki-67, MiB protein, and the estrogen receptor. HGH fragment 176-191 enhances the toxicity of Doxorubicin (HY-15142A)-loaded Chitosan nanoparticles against breast cancer .

HY-P2090A

Angiopeptin TFA	Somatostatin Receptor Adenylate Cyclase	Cardiovascular Disease
Angiopeptin TFA, a cyclic octapeptide analogue of somatostatin, is a weak sst₂/sst₅ receptor partial agonist with IC₅₀ values of 0.26 nM and 6.92 nM, respectively. Angiopeptin TFA is a potent inhibitor of growth hormone release and *insulin-like growth* factor-1 (IGF-1) production. Angiopeptin TFA inhibits adenylate cyclase** or stimulates extracellular acidification. Angiopeptin TFA has the potential for coronary atherosclerosis research .

HY-P3056

GHRF, ovine	GHSR	Endocrinology
GHRF, ovine is a growth hormone-releasing factor. GHRF is a specific mediator for the effects of hypoglycemia upon the release of pituitary growth hormone (GH) .

HY-P4750

Acetyl-(D-Arg2)-GRF (1-29) amide (human)	GHSR	Endocrinology
Acetyl-(D-Arg2)-GRF (1-29) amide (human) is an antagonist of growth hormone releasing factor (GRF). Acetyl-(D-Arg2)-GRF (1-29) amide (human) inhibits the release of growth hormone (GH) and can be used for endocrine research .

HY-P1460

His-[D-2-ME-Trp]-Ala	GHR	Others
His-[D-2-ME-Trp]-Ala is a fragment of the growth hormone hexarelin.

HY-19884A

Relamorelin acetate RM-131 acetate; BIM-28131 acetate	GHSR	Metabolic Disease
Relamorelin (RM-131) acetate, a pentapeptide ghrelin analog, is a selective *ghrelin/growth hormone* secretagogue receptor (GHSR) agonist with a K_i of 0.42 nM for GHS-1a** receptor. Relamorelin acetate is centrally penetrant. Relamorelin acetate increases growth hormone levels and accelerates gastric emptying. Relamorelin acetate has the potential for cachexia, gastroparesis, and gastric/intestinal dysmobility disorders research .

HY-P4904

RFRP-3 (rat) Neuropeptide NPVF (rat)	Peptides	Neurological Disease
RFRP-3 (rat) is a neuropeptide. RFRP-3 (rat) inhibits gonadotropin secretion, causing a marked increase in ghrelin mRNA and plasma growth hormone levels .

HY-P3397

JV-1-36	GHR	Cancer
JV-1-36 is a growth hormone-releasing hormone (GHRH) antagonist. JV-1-36 inhibits the production of reactive oxygen species in A549 lung cancer cells. JV-1-36 can be used to study the effect of GHRH antagonists in vitro .

HY-P0084A

Cyclic somatostatin acetate SRIF-14 acetate; Somatostatin-14 acetate	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
Cyclic somatostatin (SRIF-14) acetate is a growth hormone-release inhibiting factor used in the research of severe, acute hemorrhages of gastroduodenal ulcers. Cyclic somatostatin acetate is a neuropeptide co-stored with acetylcholine in the cardiac parasympathetic innervation, exerts influences directly on contraction of ventricular cardiomyocytes. Cyclic somatostatin acetate inhibits the contractile response of isoprenaline with an IC₅₀ value of 13 nM. Cyclic somatostatin acetate can be used for the research of cardiovascular disease .

HY-W091365

Boc-Asn(Xan)-OH N-Boc-N'-xanthyl-L-asparagine	Amino Acid Derivatives	Others
Boc-Asn(Xan)-OH (N-Boc-N'-xanthyl-L-asparagine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize locust fat growth hormone .

HY-P0211

[Ac-Tyr1,D-Phe2]GRF 1-29, amide (human)	GCGR	Cardiovascular Disease
[Ac-Tyr1,D-Phe2]GRF 1-29, amide (human), a growth hormone releasing factor (GRF) analogue, is a vasoactive intestinal peptide (VIP) antagonist .

HY-P3607

GHRF, bovine bGRF(1-44)-NH2	GHSR	Endocrinology
GHRF, bovine (bGRF(1-44)-NH2) is the bovine growth hormone (GH)-releasing factor (GHRF). GHRF, bovine increases the release of bovine GH, and shows a synergistic effect with Hydrocortisone (HY-N0583) .

HY-P4716

Boc-D-Trp(For)-OH	Amino Acid Derivatives	Inflammation/Immunology
Boc-D-Trp(For)-OH, containing the amino acid tryptophan, is synthesized by the ammonolysis of Boc-protected D-alanine, followed by cyclization to form a dipeptide with ninhydrin. Boc-D-Trp(For)-OH has pharmacological properties, including inhibition of growth hormone release, induction of sleep and antiinflammatory .

HY-P1366A

des-Gln14-Ghrelin TFA	GHSR	Metabolic Disease
des-Gln14-Ghrelin TFA is a second endogenous ligand for the growth hormone secretagogue receptor. a). des-Gln14-ghrelin potently induces increases in [Ca ²⁺]i in CHO-GHSR62 cells, with an EC₅₀ of 2.4 nM .

HY-P2090

Angiopeptin	Somatostatin Receptor Adenylate Cyclase	Cardiovascular Disease
Angiopeptin, a cyclic octapeptide analogue of somatostatin, is a weak sst₂/sst₅ receptor partial agonist with IC₅₀ values of 0.26 nM and 6.92 nM, respectively. Angiopeptin is a potent inhibitor of growth hormone release and *insulin-like growth* factor-1 (IGF-1) production. Angiopeptin inhibits adenylate cyclase** or stimulates extracellular acidification. Angiopeptin has the potential for coronary atherosclerosis research .

HY-P1777A

IGF-I (24-41) TFA Insulin-like growth Factor I (24-41) TFA	IGF-1R	Metabolic Disease Inflammation/Immunology
IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) TFA is amino acids 24 to 41 fragment of IGF-I. IGF-I TFA, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I TFA is partly responsible for systemic growth hormone (GH) activities. IGF-I TFA has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) TFA regulates somatic growth and behavioral development .

Cat. No.	Product Name	Target	Research Area	Image

HY-P99932

Eftansomatropin alfa TJ-101; GX-H9; hGH-hyFc; HL-2356	Inhibitory Antibodies	Metabolic Disease
Eftansomatropin alfa (GX-H9) is a fusion protein composed of rhGH (growth hormone) and immunoglobulin fragments. In Eftansomatropin alfa, rhGH is fused to a hybrid Fc domain comprising sequences of both IgD and IgG4. Eftansomatropin alfa can be used for the study of growth hormone deficiency (GHD) .

HY-P99924

Efpegsomatropin	GHR	Others
Efpegsomatropin is a long-acting human growth hormone-Fc conjugate. Efpegsomatropin is applicable for biochemical research .

HY-P991358

XOMA-213 LFA-102; X213	Estrogen Receptor/ERR STAT Akt	Cancer
XOMA-213 (LFA-102; X213) is a human monoclonal antibody (mAb) targeting the prolactin receptor (PRLR), with a K_d value of 2 nM against the human target. XOMA-213 blocks PRL-induced cell proliferation and inhibits the activation of multiple PRLR ligands, including PRL and human growth hormone (hGH). XOMA-213 suppresses PRL-induced phosphorylation of Stat5, Akt and ERK1/2 in cells. XOMA-213 induces tumor regression, delays disease progression, and inhibits PRLR signaling as well as tumor growth. XOMA-213 can be used in research related to breast cancer .

HY-P990966

Redalsomatropin alfa JR-142	GHR IGF-1R	Others
Redalsomatropin alfa (JR-142) is a recombinant long-acting growth hormone. Redalsomatropin alfa extends its half-life through fusion with modified serum albumin. Redalsomatropin alfa is well-tolerated and can maintain IGF-1 levels. Redalsomatropin alfa can be used in research related to growth hormone deficiency .

HY-P990721

Inpegsomatropin	GHR	Endocrinology
Inpegsomatropin is a pegylated long-acting recombinant human growth hormone .

HY-164147

Somapacitan NN-8640	Drug Derivative	Metabolic Disease
Somapacitan is a growth hormone analog. Somapacitan is used for research on growth hormone deficiency .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0384

Homovanillic acid Vanilacetic acid	Monophenols Immune System Disorder Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Phenols Endocrine diseases Metabolic Disease Nervous System Disorder Endogenous metabolite Disease Research Fields	Drug Metabolite Endogenous Metabolite Autophagy
Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-N0848

Epibrassinolide 15+ Cited Publications 24-Epibrassinolide; B1105; BP55	Structural Classification Natural Products Classification of Application Fields Plants Biological Pesticide Research Agricultural Research Brassinolide Phytohormone Brassicaceae Brassica campestris L. Disease Research Fields Source Classification Cancer	Environmental Pollutants Apoptosis
Epibrassinolide (24-Epibrassinolide) is a ubiquitously occurring plant growth hormone which shows great potential to alleviate heavy metals and pesticide stress in plants . Epibrassinolide is a potential apoptotic inducer in various cancer cells without affecting the non-tumor cell growth .

HY-W016784

Indole-3-acetamide 2 Publications Verification	Alkaloids Human Gut Microbiota Metabolites Microorganisms Auxin Classification of Application Fields Other Diseases Phytohormone Endogenous metabolite Disease Research Fields Indole Alkaloids Source Classification Agricultural Research	Endogenous Metabolite
Indole-3-acetamide is a biosynthesis intermediate of 3-Indoleacetic acid (HY-18569). Indole-3-acetic acid is the most common natural plant growth hormone of the auxin class .

HY-W096638A

Glycerophosphocholine (S)-Glycerolphosphocholine	Structural Classification Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Endogenous Metabolite
Glycerophosphocholine ((S)-Glycerolphosphocholine) is an orally active metabolite that crosses the blood-brain barrier. Glycerophosphocholine acts as a precursor of acetylcholine, a specific marker for phosphatidylcholine breakdown, a major water-soluble storage form of choline, and an intermediate in phosphatidylcholine metabolism. Glycerophosphocholine is specifically elevated in the cerebrospinal fluid of Alzheimer's disease models, and it also promotes growth hormone secretion and fat oxidation. Glycerophosphocholine is also a potential biomarker for breast cancer .

HY-N12348

Emoghrelin	Quinones Anthraquinones Polygonaceae Fallopia multiflora (Thunb.) Harald. Plants Source Classification	GHSR
Emoghrelin, isolated from? Heshouwu Polygonum multiflorum, stimulates growth hormone secretion via activation of the ghrelin receptor .

HY-N0384R

Homovanillic acid (Standard) Vanilacetic acid (Standard)	Monophenols Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Phenols Endocrine diseases Nervous System Disorder Endogenous metabolite	Reference Standards Autophagy Endogenous Metabolite Drug Metabolite
Homovanillic acid (Standard) (Vanilacetic acid (Standard)) is the analytical standard of Homovanillic acid (HY-N0384). This product is intended for research and analytical applications. Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-N0848R

Epibrassinolide (Standard) 24-Epibrassinolide (Standard); B1105 (Standard); BP55 (Standard)	Structural Classification Natural Products Plants Brassicaceae Brassica campestris L. Source Classification	Reference Standards Apoptosis
Epibrassinolide (Standard) is the analytical standard of Epibrassinolide. This product is intended for research and analytical applications. Epibrassinolide (24-Epibrassinolide) is a ubiquitously occurring plant growth hormone which shows great potential to alleviate heavy metals and pesticide stress in plants[1]. Epibrassinolide is a potential apoptotic inducer in various cancer cells without affecting the non-tumor cell growth[2].

HY-W016784R

Indole-3-acetamide (Standard)	Alkaloids Structural Classification Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Indole Alkaloids Source Classification	Reference Standards Endogenous Metabolite
Indole-3-acetamide (Standard) is the analytical standard of Indole-3-acetamide. This product is intended for research and analytical applications. Indole-3-acetamide is a biosynthesis intermediate of indole-3-acetic acid (HY-18569). Indole-3-acetic acid is the most common natural plant growth hormone of the auxin class[1].

HY-N14742

Pteridic acid A	Natural Products Microorganisms Source Classification	Others
Pteridic acid A is a plant growth promoter. Pteridic acid A has Auxin-like plant growth hormone activity, and 1 nM can promote the growth of legumes and other plant roots .

HY-N14751

Pteridic acid B	Natural Products Microorganisms Source Classification	Others
Pteridic acid B is a plant growth promoter. Pteridic acid B has Auxin-like plant growth hormone activity, and 1 nM can promote the growth of legumes and other plant roots .

HY-N13800

3-O-Debenzoylzeylenone	Structural Classification Uvaria grandiflora Roxb. Other Phenylpropanoids Phenylpropanoids Plants Annonaceae Source Classification	Phytohormone
3-O-Debenzoylzeylenone is a polyoxygenated cyclohexene plant growth hormone that exists in the leaves of Uvaria purpurea and the aerial parts of Uvaria grandiflora. 3-O-Debenzoylzeylenone is an auxin analog that inhibits root growth and promotes shoot growth of Lactuca sativa seedlings. 3-O-Debenzoylzeylenone exhibits cytotoxicity against various cancer cells and can be used in studies related to lung cancer, melanoma, epidermoid carcinoma, liver cancer, gastric cancer, colon adenocarcinoma, acute leukemia, breast cancer, and prostate cancer .

Species:	Human (11) Rhesus Macaque (1) Rat (3) Mouse (4)
Tag:	SUMO (1) His (9) Tag Free (3) Avi (3) Fc (8)
Source:	HEK293 (14) CHO (1) E. coli (4)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P7360

	GH/Somatotropin Protein, Human (CHO) rHuGH; Somatotropin; GH-N; GH1; growth hormone; growth hormone 1; Pituitary growth hormone	Human	CHO
	GH Protein, Human (CHO) is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration, which can be used for the study of growth disorders.

HY-P73085

	GH/Somatotropin Protein, Human (His) rHuGH; Somatotropin; GH-N; GH1; growth hormone; growth hormone 1; Pituitary growth hormone	Human	E. coli
	Growth hormone (GH) plays a key role in growth control, stimulating the release of insulin-like growth factor 1 (IGF-1) from the liver and tissues to promote body growth. It regulates myoblast differentiation and proliferation and contributes significantly to overall organismal development. GH/Somatotropin Protein, Human (His) is the recombinant human-derived GH/Somatotropin protein, expressed by E. coli , with N-10*His labeled tag.

HY-P700610

	GH/Somatotropin Protein, Human (Biotinylated, HEK293, N-His, C-Avi) rHuGH; Somatotropin; GH-N; GH1; growth hormone; growth hormone 1; Pituitary growth hormone	Human	HEK293
	Growth hormone (GH) plays a key role in growth control, stimulating the release of insulin-like growth factor 1 (IGF-1) from the liver and tissues to promote body growth. It regulates myoblast differentiation and proliferation and contributes significantly to overall organismal development. GH/Somatotropin Protein, Human (Biotinylated, HEK293, N-His, C-Avi) is the recombinant human-derived GH/Somatotropin protein, expressed by HEK293 , with C-Avi, N-10*His labeled tag.

HY-P7183

	GH/Somatotropin Protein, Human rHuGH; Somatotropin; GH-N; GH1; growth hormone; growth hormone 1; Pituitary growth hormone	Human	E. coli
	GH Protein, Human is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration, which can be used for the study of growth disorders.

HY-P70261

	GH/Somatotropin Protein, Mouse rMuSomatotropin/GH; Somatotropin; growth hormone; Gh1; Gh	Mouse	E. coli
	GH/Somatotropin Protein, Mouse is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration, which can be used for the growth disorders research.

HY-P72204

	Growth Hormone R/GHR Protein, Human (His-SUMO) GH receptor; GH-binding protein; GHBP; GHBP, included; GHR; GHR_HUMAN; growth hormone binding protein; growth hormone receptor; growth hormone receptor precursor; growth hormone-binding protein; growth hormone-binding protein, included; Increased responsiveness to growth hormone, included; Serum binding protein; Serum-binding protein; Somatotropin receptor	Human	E. coli
	Growth Hormone R (GHR) is the receptor for pituitary growth hormone, crucial in postnatal body growth regulation. Binding to its ligand activates the JAK2/STAT5 pathway, facilitating intracellular signaling. The soluble form, GHBP (Growth Hormone Binding Protein), acts as a growth hormone reservoir in the bloodstream. GHBP may modulate or inhibit growth hormone signaling, contributing to intricate growth process regulation. Growth Hormone R/GHR Protein, Human (His-SUMO) is the recombinant human-derived Growth Hormone R/GHR protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.

HY-P70850

	Growth Hormone R/GHR Protein, Mouse (HEK293, Fc) growth hormone binding protein; growth hormone receptor; serum binding protein; Somatotropin receptor; GHR; GH receptor; GHBP	Mouse	HEK293
	Growth Hormone R/GHR Protein, especially in its soluble form GHBP, acts as a plasma reservoir for growth hormone. GHBP not only regulates growth hormone availability but also potentially modulates or inhibits growth hormone signaling. This dual role highlights GHBP's regulatory impact on the intricate signaling pathways associated with growth hormone activity in the circulatory system. Growth Hormone R/GHR Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Growth Hormone R/GHR protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P73087

	Growth Hormone R/GHR Protein, Mouse (HEK293, His) growth hormone receptor; GH receptor GHBP; Ghr	Mouse	HEK293
	Growth hormone R/GHR protein, as a receptor for pituitary growth hormone, plays a crucial role in regulating postpartum body growth. Ligand binding activates the JAK2/STAT5 pathway, affecting downstream signaling in growth regulation. Growth Hormone R/GHR Protein, Mouse (HEK293, His) is the recombinant mouse-derived Growth Hormone R/GHR protein, expressed by HEK293 , with C-His labeled tag.

HY-P73088

	Growth Hormone R/GHR Protein, Rat (HEK293, Fc) growth hormone receptor; GH receptor GHBP; Ghr	Rat	HEK293
	Growth Hormone R/GHR Protein, a receptor for pituitary growth hormone, regulates postnatal body growth by activating the JAK2/STAT5 pathway upon ligand binding.Its soluble form, GHBP, acts as a plasma reservoir for growth hormone and potentially modulates or inhibits GH signaling.Growth Hormone R/GHR Protein, Rat (HEK293, Fc) is the recombinant rat-derived Growth Hormone R/GHR protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P73089

	Growth Hormone R/GHR Protein, Rat (HEK293, His) growth hormone receptor; GH receptor GHBP; Ghr	Rat	HEK293
	Growth Hormone R/GHR Protein, a receptor for pituitary growth hormone, regulates postnatal body growth by activating the JAK2/STAT5 pathway upon ligand binding.Its soluble form, GHBP, acts as a plasma reservoir for growth hormone and potentially modulates or inhibits GH signaling.Growth Hormone R/GHR Protein, Rat (HEK293, His) is the recombinant rat-derived Growth Hormone R/GHR protein, expressed by HEK293 , with C-His labeled tag.

HY-P73086

	Growth Hormone R/GHR Protein, Mouse (HEK293, His-Fc) growth hormone receptor; GH receptor GHBP; Ghr	Mouse	HEK293
	Growth hormone R/GHR protein, as a receptor for pituitary growth hormone, plays a crucial role in regulating postpartum body growth. Ligand binding activates the JAK2/STAT5 pathway, affecting downstream signaling in growth regulation. Growth Hormone R/GHR Protein, Mouse (HEK293, His-Fc) is the recombinant mouse-derived Growth Hormone R/GHR protein, expressed by HEK293 , with C-hFc, C-His labeled tag.

HY-P70240

	Somatoliberin/GHRH Protein, Human (HEK293, Fc) rHuSomatoliberin/GHRH, Fc; Somatoliberin; growth hormone-releasing factor; Somatocrinin; Somatorelin; growth hormone-releasing hormone; GHRH; GHRF	Human	HEK293
	The ghrelin/GHRH protein, also known as GRF (Growth Hormone Releasing Factor), is released by the hypothalamus and plays a key role in growth hormone regulation. It stimulates the pituitary gland to secrete growth hormone, which coordinates body growth and development. Somatoliberin/GHRH Protein, Human (HEK293, Fc) is the recombinant human-derived Somatoliberin/GHRH protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P702568

	Growth Hormone R/GHR Protein, Human (HEK293, His) GHR; GHBP; GH receptor	Human	HEK293
	Growth Hormone R (GHR) is the receptor for pituitary growth hormone, crucial in postnatal body growth regulation. Binding to its ligand activates the JAK2/STAT5 pathway, facilitating intracellular signaling. The soluble form, GHBP (Growth Hormone Binding Protein), acts as a growth hormone reservoir in the bloodstream. GHBP may modulate or inhibit growth hormone signaling, contributing to intricate growth process regulation. Growth Hormone R/GHR Protein, Human (HEK293, His) is the recombinant human-derived Growth Hormone R/GHR protein, expressed by HEK293 , with C-His labeled tag.

HY-P72024

	Growth Hormone R/GHR Protein, Human (HEK293, hFc) Somatotropin receptor Serum-binding protein	Human	HEK293
	Growth Hormone R (GHR) is the receptor for pituitary growth hormone, crucial in postnatal body growth regulation. Binding to its ligand activates the JAK2/STAT5 pathway, facilitating intracellular signaling. The soluble form, GHBP (Growth Hormone Binding Protein), acts as a growth hormone reservoir in the bloodstream. GHBP may modulate or inhibit growth hormone signaling, contributing to intricate growth process regulation. Growth Hormone R/GHR Protein, Human (HEK293, hFc) is the recombinant human-derived Growth Hormone R/GHR protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P78726

	Growth Hormone R/GHR Protein, Rhesus macaque (HEK293, Fc) GHR; GHBP; GH receptor	Rhesus Macaque	HEK293
	GHR Protein, a cell surface receptor, is involved in growth regulation and metabolism. Dysregulation of GHR Protein has been linked to conditions such as growth hormone deficiency and metabolic disorders. Targeting GHR Protein may offer potential therapeutic interventions in these conditions by regulating growth, improving metabolism, and managing related disorders. Growth Hormone R/GHR Protein, Rhesus macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived Growth Hormone R/GHR protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P78869

	Growth Hormone R/GHR Protein, Human (Biotinylated, HEK293, His) GHR; GHBP; GH receptor	Human	HEK293
	Growth Hormone R (GHR) is the receptor for pituitary growth hormone, crucial in postnatal body growth regulation. Binding to its ligand activates the JAK2/STAT5 pathway, facilitating intracellular signaling. The soluble form, GHBP (Growth Hormone Binding Protein), acts as a growth hormone reservoir in the bloodstream. GHBP may modulate or inhibit growth hormone signaling, contributing to intricate growth process regulation. Growth Hormone R/GHR Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived Growth Hormone R/GHR protein, expressed by HEK293 , with C-His labeled tag.

HY-P700413

	Growth Hormone R/GHR Protein, Human (Biotinylated, HEK293, mFc-Avi) Somatotropin receptor Serum-binding protein	Human	HEK293
	Growth Hormone R (GHR) is the receptor for pituitary growth hormone, crucial in postnatal body growth regulation. Binding to its ligand activates the JAK2/STAT5 pathway, facilitating intracellular signaling. The soluble form, GHBP (Growth Hormone Binding Protein), acts as a growth hormone reservoir in the bloodstream. GHBP may modulate or inhibit growth hormone signaling, contributing to intricate growth process regulation. Growth Hormone R/GHR Protein, Human (Biotinylated, HEK293, mFc-Avi) is the recombinant human-derived Growth Hormone R/GHR protein, expressed by HEK293 , with C-Avi, C-mFc labeled tag.

HY-P705026

	Growth Hormone R/GHR Protein, Human (Biotinylated, HEK293, Fc-Avi) Somatotropin receptor Serum-binding protein	Human	HEK293

HY-P77466

	PRL8A4 Protein, Rat (HEK293, His) Prolactin-8A4; growth hormone-related placental protein 3; PLP-H; Prlph	Rat	HEK293
	The PRL8A4 protein is involved in regulating cells in the basal zone of the placenta, suggesting a potential impact on placental development. Although important, the specific functions and molecular mechanisms of PRL8A4 in these cells require further exploration. PRL8A4 Protein, Rat (HEK293, His) is the recombinant rat-derived PRL8A4 protein, expressed by HEK293 , with C-His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-18569S3

3-Indoleacetic acid-d7
3-Indoleacetic acid-d₇ is the deuterium labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division .

HY-18569S4

3-Indoleacetic acid-13C6
3-Indoleacetic acid- ¹³C₆ is the ¹³C labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division .

HY-N0384S2

Homovanillic acid-d5
Homovanillic acid-d₅ (Vanilacetic acid-d₅) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-18569S2

3-Indoleacetic acid-2,2-d2
3-Indoleacetic acid-2,2-d₂ is the deuterium labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division .

HY-W016784S

Indole-3-acetamide-d5
Indole-3-acetamide-d₅ is the deuterium labeled Indole-3-acetamide . Indole-3-acetamide is a biosynthesis intermediate of indole-3-acetic acid (HY-18569). Indole-3-acetic acid is the most common natural plant growth hormone of the auxin class .

HY-18569S1

3-Indoleacetic acid-d4
3-Indoleacetic acid-d₄ (Indole-3-acetic acid-d₄; 3-IAA-d₄) is the deuterium labeled 3-Indoleacetic acid (HY-18569) . 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division .

HY-176258S

Growth Hormone 22, Arg-13C6,15N4, Lys-13C6,15N2

HY-N0384S

Homovanillic acid-d3
Homovanillic acid-d₃ (Vanilacetic acid-d₃) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-N0384S1

Homovanillic acid-d2
Homovanillic acid-d₂ (Vanilacetic acid-d₂) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-176351S

Growth hormone 22, U-15N
Growth hormone 22, U- ¹⁵N is the ¹⁵N-labeled Growth hormone 22.

HY-B1161S

Methoprene-d7
Methoprene-d₇ is the deuterium labeled Methoprene . Methoprene, an insect juvenile growth hormone mimic, is a growth-regulating insecticide that manifests its toxicity to target organisms by acting as a juvenile hormone agonist .

HY-W777477

Homovanillic Acid-13C6
Homovanillic Acid- ¹³C₆ (Vanilacetic acid- ¹³C₆) is the ¹³C-labeled Homovanillic acid (HY-N0384). Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.

HY-N0384S4

Homovanillic acid-d3-1
Homovanillic acid-d₃-1 (Vanilacetic acid-d₃-1) is deuterated labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-N0384S3

Homovanillic acid-13C6,18O
Homovanillic acid- ¹³C₆, ¹⁸O (Vanilacetic acid- ¹³C₆, ¹⁸O) is the ¹³C- and ¹⁸O-labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-N0384S5

Homovanillic acid-13C,d3
Homovanillic acid- ¹³C,d₃ (Vanilacetic acid- ¹³C,d₃) is ¹³C and deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

Host:	Rabbit (6)
Reactivity:	Human (6) Rat (1) Mouse (2)
Application:	IHC-P (5) IP (2) WB (3)
Isotype:	IgG (6)
Conjugation:	Non-conjugated (6) Biotin (4)
Clonality:	Polyclonal (1) Monoclonal (3) Recombinant (3)
Modification:	Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P83522

	Growth Hormone 1 Antibody (YA3267) GH1; Somatotropin; growth hormone; GH; GH-N; growth hormone 1; Pituitary growth hormone	WB, IHC-P, IP	Human
	Growth Hormone 1 Antibody (YA3267) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Growth Hormone 1.

HY-P83522A

	Growth Hormone 1 Antibody (YA3267)(PBS only) GH1; Somatotropin; growth hormone; GH; GH-N; growth hormone 1; Pituitary growth hormone	WB, IHC-P, IP	Human
	Growth Hormone 1 Antibody (YA3267) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Growth Hormone 1.

HY-P81107

	Growth hormone receptor Antibody GH receptor; GHBP; GHR; growth hormone receptor precursor; Serum binding protein; Somatotropin receptor; GHR_HUMAN.	WB	Human, Mouse, Rat
	Growth hormone receptor Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Growth hormone receptor.

HY-P810376

	Obestatin Antibody (YA9696) Appetite regulating hormone, Ghrelin 27, Ghrelin 28, Ghrelin and obestatin prepropeptide, Ghrelin, Ghrelin/obestatin prepropeptide, ghrl, GHRL_HUMAN, growth hormone releasing peptide, growth hormone secretagogue	IHC-P	Human, Mouse
	Obestatin Antibody (YA9696) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to Obestatin.

HY-P81482

	Obestatin Antibody (YA1227) GHRL; MTLRP; UNQ524/PRO1066; Appetite-regulating hormone; growth hormone secretagogue; growth hormone-releasing peptide; Motilin-related peptide; Protein M46; Ghrelin-27Ghrelin-28 (Ghrelin); Obestatin	IHC-P	Human
	Obestatin Antibody (YA1227) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Obestatin.

HY-P81482A

	Obestatin Antibody (YA1227)(PBS only) GHRL; MTLRP; UNQ524/PRO1066; Appetite-regulating hormone; growth hormone secretagogue; growth hormone-releasing peptide; Motilin-related peptide; Protein M46; Ghrelin-27Ghrelin-28 (Ghrelin); Obestatin	IHC-P	Human
	Obestatin Antibody (YA1227) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Obestatin.

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Cat. No.	Product Name		Classification

HY-164419A

Atesidorsen sodium COR-004 sodium; ATL1103 sodium; ISIS 227452 sodium		Antisense Oligonucleotides
Atesidorsen sodium is a second-generation, antisense oligomer designed to inhibit translation of human growth hormone receptor (GHR) mRNA

HY-153485

Cimdelirsen ISIS 766720; IONIS-GHR-LRx		Antisense Oligonucleotides
Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients.

HY-153485A

Cimdelirsen sodium ISIS 766720 sodium; IONIS-GHR-LRx sodium		Antisense Oligonucleotides
Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients.

HY-164419

Atesidorsen COR-004; ATL1103; ISIS 227452		Antisense Oligonucleotides
Atesidorsen is a second-generation, antisense oligomer designed to inhibit translation of human growth hormone receptor (GHR) mRNA

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