JV-1-36 acetate
Based on 1 Customer Validation
JV-1-36 acetate is a growth hormone-releasing hormone (GHRH) antagonist. JV-1-36 acetate inhibits the production of reactive oxygen species in A549 lung cancer cells. JV-1-36 can be used to study the effect of GHRH antagonists in vitro .
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- Pureté: 99.93%
- Formule: C172H284ClN53O41.xC2H4O2
- Masse moléculaire:3785.88 (free base)
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Stockage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
IC50: growth hormone-releasing hormone (GHRH)[1].
JV-1-36 (0.01-15 μM; 8 h) reduces cell viability in A549 cells at higher concentrations (5-15 μM), and (2-15 μM; 8 h) also decreases cell viability in Hela cells[1].
JV-1-36 (1 μM; 8 h) significantly reduces the production of ROS induced by H2O2 (0.1 mM; 8 h) in A549 lung cancer cells, exerting antioxidant effects[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Masse moléculaire 3785.88 (free base)
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Formule C172H284ClN53O41.xC2H4O2
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Color White to off-white
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Sequence
{N-(2-phenylacetyl)}-Tyr-{d-Arg}-Asp-Ala-Ile-{4-Cl-Phe}-Thr-Asn-{Har}-{Tyr(Me)}-Arg-Lys-Val-Leu-{Abu}-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-{Nle}-{d-Arg}-{Har}-NH2
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Sequence Shortening
{N-(2-phenylacetyl)}-Y-{d-Arg}-DAI-{4-Cl-Phe}-TN-{Har}-{Tyr(Me)}-RKVL-{Abu}-QLSARKLLQDI-{Nle}-{d-Arg}-{Har}-NH2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvant et solubilité
H2O : 100 mg/mL (Need ultrasonic)
Pureté et documentation
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Fiche technique (288 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
JV-1-36 acetate Related Classifications
HY-P3397A Related Classifications
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