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  4. Monoclonal Antibodies Recombinant Antibodies
  5. Obestatin Antibody (YA1227)

Obestatin Antibody (YA1227)

Cat. No.: HY-P81482
User Guide for Antibodies Technical Support

Obestatin Antibody (YA1227) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Obestatin.

For research use only. We do not sell to patients.

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20 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
50 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
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250 μL   Get quote  
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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

Obestatin Antibody (YA1227) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Obestatin.
Host

Rabbit
Clonality

Recombinant,Monoclonal
Molecular Weight
Predicted band size: 13 kDa;
Observed band size: 13 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

A synthesized peptide derived from human Obestatin
Application &
Dilution Ratio
Application Dilution Ratio
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:500-1:2000
Sensitivity Endogenous Purity Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.306.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR) (PubMed:10604470). Induces the release of growth hormone from the pituitary (PubMed:10604470). Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation; Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR) (PubMed:10604470). Induces the release of growth hormone from the pituitary (PubMed:10604470). Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation; May be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility (By similarity)
Subcellular Localization：Secreted
Expression：
Tissue_specificity:Highest level in stomach. All forms are found in serum as well. Other tissues compensate for the loss of ghrelin synthesis in the stomach following gastrectomy
Isoforms & Post-Translational Modification：Q9UBU3 has 6 isomers: Q9UBU3-1: 12911 Da (predicted); Q9UBU3-2: 12783 Da (predicted); Q9UBU3-3: 11784 Da (predicted); Q9UBU3-4: 11656 Da (predicted); Q9UBU3-5: 7460 Da (predicted); Q9UBU3-6: 9972 Da (predicted).
O-octanoylated by GOAT/MBOAT4 (PubMed:18443287). O-octanoylation or O-decanoylation is essential for ghrelin activity (PubMed:10604470). The O-decanoylated forms Ghrelin-27-C10 and Ghrelin-28-C10 differ in the length of the carbon backbone of the carboxylic acid bound to Ser-26 (PubMed:10604470). A small fraction of ghrelin, ghrelin-28-C10:1, may be modified with a singly unsaturated carboxylic acid (PubMed:10604470). Also O-acetylated and O-butyrylated on Ser-26 to minor levels (PubMed:18443287);Amidation of Leu-98 is essential for obestatin activity
Database

Entrez Gene: 51738 Human

SwissProt: Q9UBU3 Human

OMIM: 605353 Human

Research Field

Neuroscience
Synonyms
GHRL; MTLRP; UNQ524/PRO1066; Appetite-regulating hormone; Growth hormone secretagogue; Growth hormone-releasing peptide; Motilin-related peptide; Protein M46; Ghrelin-27Ghrelin-28 (Ghrelin); Obestatin
Documentation
User Guide for Antibodies (1077 KB)

Obestatin Antibody (YA1227) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Obestatin Antibody (YA1227)
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