Obestatin Antibody (YA9696)
(Synonyms: Appetite regulating hormone, Ghrelin 27, Ghrelin 28, Ghrelin and obestatin prepropeptide, Ghrelin, Ghrelin/obestatin prepropeptide, ghrl, GHRL_HUMAN, Growth hormone releasing peptide, Growth hormone secretagogue)Obestatin Antibody (YA9696) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to Obestatin.
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Host:
Rabbit
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Isotype:
IgG
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Application:
IHC-P
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Reactivity :
Human, Mouse
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:25000-50000 |
Product Details
Obestatin Antibody (YA9696) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to Obestatin.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse
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Calculated Molecular Weight Predicted band size: 13 kDa;
Recombinant protein of human Ghrelin (aa 1-117).
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Obestatin is a Precursor of the appetite-regulating peptide ghrelin, including ghrelin-27 and ghrelin-28
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Subcellular Localization
Secreted
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Expression
Tissue_Specificity: Highest level in stomach. All forms are found in serum as well. Other tissues compensate for the loss of ghrelin synthesis in the stomach following gastrectomy. -
Isoforms & Post-Translational Modification
Obestatin has 6 isoforms, Q9UBU3-1: amino acid length is 117, molecular weight is 12911 Da (predicted); Q9UBU3-2: amino acid length is 116, molecular weight is 12783 Da (predicted); Q9UBU3-3: amino acid length is 105, molecular weight is 11784 Da (predicted); Q9UBU3-4: amino acid length is 104, molecular weight is 11656 Da (predicted); Q9UBU3-5: amino acid length is 66, molecular weight is 7460 Da (predicted); Q9UBU3-6: amino acid length is 91, molecular weight is 9972 Da (predicted).
O-octanoylated by GOAT/MBOAT4. O-octanoylation or O-decanoylation is essential for ghrelin activity. The O-decanoylated forms Ghrelin-27-C10 and Ghrelin-28-C10 differ in the length of the carbon backbone of the carboxylic acid bound to Ser-26. A small fraction of ghrelin, ghrelin-28-C10:1, may be modified with a singly unsaturated carboxylic acid. Also O-acetylated and O-butyrylated on Ser-26 to minor levels -
SwissProt ID
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Synonyms
Appetite regulating hormone, Ghrelin 27, Ghrelin 28, Ghrelin and obestatin prepropeptide, Ghrelin, Ghrelin/obestatin prepropeptide, ghrl, GHRL_HUMAN, Growth hormone releasing peptide, Growth hormone secretagogue
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