Search Result

Results for "

α-amylase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amylases (84) Amyloid-β (1) Angiotensin-converting Enzyme (ACE) (1) Apoptosis (3) Bacterial (1) Bcl-2 Family (1) Biochemical Assay Reagents (10) Caspase (1) Cholinesterase (ChE) (3) COX (3) Dipeptidyl Peptidase (6) DNA/RNA Synthesis (1) Drug Intermediate (1) Drug Metabolite (1) Endogenous Metabolite (5) Environmental Pollutants (1) Fatty Acid Synthase (FASN) (2) Fungal (2) GLUT (3) Glycosidase (59) HDAC (1) Lipase (2) MDM-2/p53 (1) Monoamine Oxidase (1) NF-κB (7) NO Synthase (1) NOD-like Receptor (NLR) (2) P-glycoprotein (1) P2Y Receptor (1) p38 MAPK (1) Parasite (1) PARP (1) Phosphatase (2) PPAR (2) Pregnane X Receptor (PXR) (1) Pyroptosis (2) Reactive Oxygen Species (ROS) (2) Reference Standards (4) SARS-CoV (1) SOD (1) TNF Receptor (1) Tyrosinase (1) β-glucuronidase (1)
By Research Areas:	Cancer (13) Cardiovascular Disease (2) Endocrinology (4) Infection (4) Inflammation/Immunology (25) Metabolic Disease (91) Neurological Disease (5)

By Targets:

Amylases (84)

Amyloid-β (1)

Angiotensin-converting Enzyme (ACE) (1)

Apoptosis (3)

Bacterial (1)

Bcl-2 Family (1)

Biochemical Assay Reagents (10)

Caspase (1)

Cholinesterase (ChE) (3)

COX (3)

Dipeptidyl Peptidase (6)

DNA/RNA Synthesis (1)

Drug Intermediate (1)

Drug Metabolite (1)

Endogenous Metabolite (5)

Environmental Pollutants (1)

Fatty Acid Synthase (FASN) (2)

Fungal (2)

GLUT (3)

Glycosidase (59)

HDAC (1)

Lipase (2)

MDM-2/p53 (1)

Monoamine Oxidase (1)

NF-κB (7)

NO Synthase (1)

NOD-like Receptor (NLR) (2)

P-glycoprotein (1)

P2Y Receptor (1)

p38 MAPK (1)

Parasite (1)

PARP (1)

Phosphatase (2)

PPAR (2)

Pregnane X Receptor (PXR) (1)

Pyroptosis (2)

Reactive Oxygen Species (ROS) (2)

Reference Standards (4)

SARS-CoV (1)

SOD (1)

TNF Receptor (1)

Tyrosinase (1)

β-glucuronidase (1)

By Research Areas:

Cancer (13)

Cardiovascular Disease (2)

Endocrinology (4)

Infection (4)

Inflammation/Immunology (25)

Metabolic Disease (91)

Neurological Disease (5)

123

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-132179

Fucoidan Maximum Cited Publications 6 Publications Verification	Glycosidase	Cardiovascular Disease Metabolic Disease Cancer
Fucoidan, a biologically active polysaccharide, is an efficient inhibitor of α-amylase and α-glucosidase. Anticoagulant, antitumor, antioxidant and antisteatotic activities .

HY-B2193

*α-Amylase* 2 Publications Verification	Environmental Pollutants Amylases	Others
α-Amylase is a hydrolase enzyme that catalyses the hydrolysis of internal α-1, 4-glycosidic linkages in starch to yield products like glucose and maltose.

HY-N1425

Tiliroside 3 Publications Verification	Others	Metabolic Disease
Tiliroside, a glycosidic flavonoid, possesses anti-diabetic activities. Tiliroside is a noncompetitive inhibitor of *α-amylase* with a K_i value of 84.2 μM. Tiliroside inhibits carbohydrate digestion and glucose absorption in the gastrointestinal tract .

HY-W009694

3,5-Dinitrosalicylic acid	Biochemical Assay Reagents	Others
3,5-Dinitrosalicylic acid the derivative of salicylic acid. 3,5-Dinitrosalicylic acid is used in the α-amylase assay, carbohydrase assay, and for the colorimetric determination of reducing substances .

HY-N0668

Rubusoside 2 Publications Verification	GLUT Amylases NF-κB	Metabolic Disease Inflammation/Immunology Cancer
Rubusoside is a diterpene glycoside that is also a sweetener and solubilizer with anti-angiogenic, anti-cancer, anti-obesity, anti-allergic and anti-asthmatic effects. Rubusoside attenuates airway hyperresponsiveness and reduces inflammatory cells in bronchoalveolar lavage fluid (BALF), reducing OVA (HY-W250978)-induced airway inflammation. Rubusoside also prevents palmitic acid-induced lipotoxicity in pancreatic INS-1 cells, reduces the transport of human glucose transporters GLUT-1 and fructose GLUT-5, and inhibits NF-κB and α-amylase (α-amylase) .

HY-P2968

Bacterial α-Amylase	Amylases	Others
Bacterial α-Amylase catalyses the hydrolysis of internal α-1,4-glycosidic linkages in starch in low molecular weight products, such glucose, maltose and maltotriose units. Bacterial α-Amylase is often used in biochemical studies .

HY-P2762

α-Amylase from Aspergillus oryzae	Amylases	Others
α-Amylase from Aspergillus oryzae is an *amylase. α-Amylase* from Aspergillus oryzae can be used for various biochemical studies .

HY-N1495

Maltopentaose Maltopentose	Amylases	Others
Maltopentaose is the shortest chain oligosaccharide. Maltopentaose is a substrate for *α-amylases. Maltopentaose can be classified as maltodextrin and is also used in a study to investigate glycation and phosphorylation of α-lactalbumin. Maltopentaose is used to study the inhibition kinetics of human pancreatic α-amylase* by dehydrodieugenol B .

HY-153102

G3-CNP	Biochemical Assay Reagents	Others
G3-CNP is an α-amylase substrate. The absorbance of G3-CNP cleavage product 2-chloro-4-nitrophenol is measured at 405 nm, which can be used to detect enzyme activity .

HY-126052

Gnetol	COX Tyrosinase HDAC	Metabolic Disease Cancer
Gnetol is a phenolic compound isolated from the root of Gnetum montanum . Gnetol potently inhibits COX-1 (IC₅₀ of 0.78 μM) and HDAC. Gnetol is a potent tyrosinase inhibitor with an IC₅₀ of 4.5 μM for murine tyrosinase and suppresses melanin biosynthesis. Gnetol has antioxidant, antiproliferative, anticancer and hepatoprotective activity. Gnetol also possesses concentration-dependent α-Amylase, α-glucosidase, and adipogenesis activities .

HY-112835

Ethylidene-4-nitrophenyl-a-D-Maltoheptaoside pNP-G7	Amylases Glycosidase	Inflammation/Immunology
Ethylidene-4-nitrophenyl-α-D-Maltoheptaoside (EPS; pNP-G7) serves as a substrate for α-amylase. In the presence of an auxiliary enzyme such as α-glucosidase (α-glucosidase), Ethylidene-4-nitrophenyl-α-D-Maltoheptaoside is degraded by amylase (Amylase) to release a chromophore, enabling the measurement of amylase activity. Ethylidene-4-nitrophenyl-α-D-Maltoheptaoside is applicable for the diagnosis of pancreatitis ^[2].

HY-N2376

Chrysin-7-O-glucuronide 1 Publications Verification	Glycosidase Amylases NF-κB	Metabolic Disease Inflammation/Immunology
Chrysin-7-O-glucuronide is a flavonoid found in Scutellaria baicalensis. Chrysin-7-O-glucuronide inhibits α-glucosidase and *α-amylase* with IC₅₀ values of 612.13 and 980.73 μg/mL. Chrysin-7-O-glucuronide suppresses NF-κB signaling activity. Chrysin-7-O-glucuronide scavenges free radicals, acts as a tight junction protector, and mitigates intestinal mucosal barrier injury. Chrysin-7-O-glucuronide can be used for the research of type 2 diabetes and severe acute pancreatitis-induced intestinal mucosal barrier injury .

HY-B2193A

α-Amylase, Human Saliva 1,4-alpha-D-Glucan-glucanohydrolase, ptyalin	Biochemical Assay Reagents	Metabolic Disease Inflammation/Immunology
α-Amylase, Human Saliva (1,4-alpha-D-Glucan-glucanohydrolase) is a hydrolase enzyme that can be isolated from human saliva. α-Amylase, Human Saliva catalyses the hydrolysis of internal α-1, 4-glycosidic linkages in starch to yield products like glucose and maltose. α-Amylase, Human Saliva can be used in life science research .

HY-B2193C

α-Amylase, Porcine Pancreatic 1,4-alpha-D-Glucan-glucanohydrolase, amy2, PPA, PA	Biochemical Assay Reagents	Others
α-Amylase, Porcine Pancreatic (1,4-alpha-D-Glucan-glucanohydrolase) is a hydrolase enzyme that can be isolated from porcine pancreatic. α-Amylase, Porcine Pancreatic catalyses the hydrolysis of internal α-1, 4-glycosidic linkages in starch to yield products like glucose and maltose. α-Amylase, Porcine Pancreatic can be used in life science research .

HY-Y0598

trans-Chalcone 2 Publications Verification Benzylideneacetophenone	Fatty Acid Synthase (FASN) Apoptosis Fungal	Inflammation/Immunology Cancer
trans-Chalcone, isolated from Aronia melanocarpa skin, is a biphenolic core structure of flavonoids precursor. trans-Chalcone is a potent fatty acid synthase (FAS) and *α-amylase* inhibitor. trans-Chalcone causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7. trans-Chalcone has antifungal and anticancer activity .

HY-N6675

Gardenia yellow	Amylases Glycosidase	Inflammation/Immunology
Gardenia yellow is a competitive inhibitor of *α-Amylase* (HY-B2193) and α-glucosidase. Gardenia yellow can bind to the catalytic sites of *α-Amylase* and α-glucosidase, inhibit starch digestion, and significantly increase the contents of resistant starch and slowly digestible starch in starch-based systems. Gardenia yellow reduces the glycemic index and hydrolysis index. Gardenia yellow can be used in diabetes-related research .

HY-N8599

Cichoriin 2 Publications Verification	Amylases Glycosidase Lipase Dipeptidyl Peptidase p38 MAPK PPAR P2Y Receptor NOD-like Receptor (NLR) SARS-CoV Pyroptosis GLUT Angiotensin-converting Enzyme (ACE) NF-κB	Infection Metabolic Disease Inflammation/Immunology
Cichoriin is an orally active coumarin glycoside with broad biological activities. Cichoriin exhibits inhibitory activities against *α-amylase, α-glucosidase, pancreatic lipase* and DPP-IV, with IC₅₀ values of 5.76, 2.94, 16.83 and 9.16 μg/mL, respectively. Cichoriin significantly improves metabolic dysfunction-associated steatohepatitis (MASH) in mice by activating the AMPK signaling pathway. Cichoriin upregulates PPAR-γ in adipose tissue and alleviates obesity and associated cardiorenal injury in rats. Cichoriin blocks monosodium urate crystal-induced activation of the NLRP3 inflammasome and cell pyroptosis by inhibiting P2Y₁₄R (IC₅₀ = 8.47 nM). In silico virtual screening reveals that Cichoriin has a strong binding affinity for SARS-CoV-2 .

HY-B2193B

α-Amylase, Human Pancreas amylase, a-amylase, 1,4-a-D-glucan glucanohydrolase, glycogenase	Biochemical Assay Reagents	Others
α-Amylase, Human Pancreas (Amylase) is a hydrolase enzyme that can be isolated from human pancreas. α-Amylase, Human Pancreas catalyses the hydrolysis of internal α-1, 4-glycosidic linkages in starch to yield products like glucose and maltose. α-Amylase, Human Pancreas can be used in life science research .

HY-N8161

Kaempferol-3,7-di-O-β-glucoside Kaempferol 3,7-diglucoside	Glycosidase Cholinesterase (ChE)	Neurological Disease
Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside), a flavonol, possesses enzyme inhibition property towards *α-amylase, α-glucosidase* and Acetylcholinesterase. Kaempferol-3,7-di-O-β-glucoside protects differentiating neuronal cells, SH-SY5Y from Amyloid β peptide-induced injury. Kaempferol-3,7-di-O-β-glucoside has the potential for Alzheimer's research .

HY-W068682

1-Hydroxyphenazine Hemipyocyanine; 1-Phenazinol; Hemi-pyocyanin	Amylases Bacterial	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
1-Hydroxyphenazine (Hemipyocyanine; 1-Phenazinol; Hemi-pyocyanin) is an inhibitor for *α-Amylase* with an IC₅₀ of 3.1 μg/mL . 1-Hydroxyphenazine exhibits anticancer and anti-inflammatory activity against cells A549, 1321N1 and RAW264.7, antifungal and antibacterial activity against strains Candida albicans, Aspergillus fumigatus, Escherichia coli and Xanthomonas campestris .

HY-W005598

2-Hydroxyquinoline	Glycosidase Amylases	Metabolic Disease
2-Hydroxyquinoline is an inhibitor of α-glucosidase and *α-amylase* with IC₅₀ values of 64.4 µg/mL and 130.5 µg/mL, respectively. 2-Hydroxyquinoline can be used in the study of diabetes .

HY-135530

Chinese gallotannin	Amylases	Metabolic Disease
Chinese gallotannin is a non-specific promiscuous *α-amylase* inhibitor with a K_i of 0.82 μg/mL for human salivary α-amylase. Chinese gallotannin can be used for the research of diabetes .

HY-N4309

Lotusine	Amylases Glycosidase	Neurological Disease Metabolic Disease Cancer
Lotusine is an orally active signaling pathway modulator and enzyme inhibitor, with an IC₅₀ of 30.60 μg/mL against *α-amylase* and an IC₅₀ of 36.15 μg/mL against α-glucosidase. Lotusine inhibits the EGFR-Akt-ERK signaling pathway by reducing the levels of phosphorylated EGFR, Akt and ERK. Lotusine induces apoptosis, triggers G₀/G₁ cell cycle arrest and inhibits cancer cell proliferation. Lotusine reduces lipid peroxidation and increases the activities of SOD, CAT and GPx. Lotusine is applicable to researches related to non-small cell lung cancer, type 2 diabetes and autism spectrum disorder .

HY-146752

α-Amylase-IN-1	Amylases	Others
α-Amylase-IN-1 is a potent *α-amylase* inhibitor with an IC_{50 of 4.46 μM .}

HY-178363

α-Amylase-IN-13	Amylases	Metabolic Disease Endocrinology
α-Amylase-IN-13 is an orally active, selective, brain-penetrant *α-amylase* inhibitor (IC₅₀ = 0.71 μM). α-Amylase-IN-13 inhibits α-amylase through a mixed type of inhibition mechanism. α-Amylase-IN-13 leads to a significant reduction in blood glucose level in diabetic rats. α-Amylase-IN-13 causes significant histopathological improvements in the kidney, liver, and pancreas. α-Amylase-IN-13 can be used for the study of diabetic complications .

HY-149008

α-Amylase-IN-3	Amylases Cholinesterase (ChE)	Inflammation/Immunology
α-Amylase-IN-3 (Compound 4) is the inhibitor for *α-Amylase, AChE* and AChE with IC₅₀s of 18.04 μM, 21.04 μM and 22.2 μM, respectively. α-Amylase-IN-3 exhibits antioxidant activity. α-Amylase-IN-3 can be used in research of diabetes and oxidative stress associated disease .

HY-200541

Dihydro-α-ionone	Others	Metabolic Disease
Dihydro-α-ionone is a volatile compound found in the essential oil of Persicaria hydropiper L. leaves. The essential oil can inhibit α-glucosidase and α-amylase activities .

HY-179141

α-Amylase/α-Glucosidase-IN-23	Amylases Glycosidase	Metabolic Disease
α-Amylase/α-Glucosidase-IN-23 (Compound 5e) is a *α-Amylase/α-Glucosidase* inhibitor with IC₅₀ values of 73.68 nM for α-glucosidase and 146.18 nM for α-amylase. α-Amylase/α-Glucosidase-IN-23 can be used in the research of hypoglycemia .

HY-N9454

Garcinoic acid	Pregnane X Receptor (PXR) COX NF-κB Amylases β-glucuronidase DNA/RNA Synthesis Amyloid-β NOD-like Receptor (NLR) Pyroptosis	Cancer
Garcinoic acid is an orally active anti-inflammatory agent that crosses the blood-brain barrier. Garcinoic acid also enhances efferocytosis and enzyme/receptor regulation, and selectively inhibits human COX-2, porcine *α-amylase, Saccharomyces cerevisiae α-glucosidase* and human DNA polymerase β (IC₅₀=11 μM), as well as activates human PXR. Garcinoic acid enhances macrophage efferocytosis via receptors such as MerTK and LRP-1, and promotes the production of pro-resolving lipid mediators. Garcinoic acid inhibits NF-κB activation and pro-inflammatory cytokine secretion, interferes with Aβ aggregation, downregulates NLRP3 inflammasome activity, and binds to targets including CD44 and EGFR to inhibit leukemia cell proliferation. The pharmacological activities of Garcinoic acid, such as antioxidant, anti-inflammatory and lipid metabolism-regulating effects, are widely used in studies related to various diseases including atherosclerosis, Alzheimer's disease, type 2 diabetes, inflammatory bowel disease and viral pneumonia .

HY-N17254

Onjisaponin R	Amylases	Metabolic Disease
Onjisaponin R is an *α-amylase* inhibitor. Onjisaponin R can be used in diabetes research .

HY-N10413

Diphlorethohydroxycarmalol	Glycosidase	Metabolic Disease
Diphlorethohydroxycarmalol, a kind of phlorotannin, is an orally active α-glucosidase and *α-amylase* inhibitor with IC₅₀s of 0.16 mM and 0.53 mM, respectively. Diphlorethohydroxycarmalol has anti-diabetic activities .

HY-178935

α-Amylase-IN-14	Amylases Reactive Oxygen Species (ROS)	Metabolic Disease Inflammation/Immunology
α-Amylase-IN-14, a derivative of Nicotinic (HY-B0143), is an *α-amylase* inhibitor and has good interactions with α-amylase protein (-5.55 kcal/mol). α-Amylase-IN-14 is a dual anti-inflammatory and anti-hyperglycemic agent. α-Amylase-IN-14 exhibits good results against DPPH and ABTS radicals. α-Amylase-IN-14 can be used for the study of diabetes .

HY-175605

α-Amylase/α-Glucosidase-IN-21	Glycosidase Amylases	Metabolic Disease
α-Amylase/α-Glucosidase-IN-21 (Compound 4) is a dual-functional inhibitor of α-Glucosidase and *α-Amylase* with IC₅₀s of 0.27 and 0.19 µg/mL for α-Glucosidase and α-Amylase, respectively. α-Amylase/α-Glucosidase-IN-21 has an antidiabetic activity.α-Amylase/α-Glucosidase-IN-21 can be used for diabetes mellitus research .

HY-133718

Acarviosin (S)-Acarviosin	Amylases	Others
Acarviosin, a pseudodisaccharide moiety, is a part of the potent inhibitor of α-amylase .

HY-155241

α-Amylase/α-Glucosidase-IN-4	Glycosidase Amylases	Metabolic Disease
α-Amylase/α-Glucosidase-IN-4 (compound 5) is a dual inhibitor of α-glucosidase (Glucosidase) and α-amylase (Amylases) with IC₅₀s of 0.15 μM and 1.10 μM, respectively. α-Amylase/α-Glucosidase-IN-4 has potential antidiabetic activity .

HY-161944

α-Amylase-IN-8	Amylases	Metabolic Disease
α-Amylase-IN-8 (compound 44) is an *α-amylase* inhibitor (IC₅₀=58.1 μM). α-Amylase-IN-8 can be used in the research of type 2 diabetes .

HY-149313

α‑Amylase-IN-1	Amylases	Metabolic Disease
α Amylase-IN-1 (Compound 11) is an *α-Amylase* inhibitor with an IC₅₀ value of 0.5509 μM. α Amylase-IN-1 has antioxidant activity with an IC₅₀ value of 53.49 μM for scavenging DPPH free radicals. IC₅₀ can be used in the study of diabetes and oxidative stress-related diseases.

HY-179511

α-Glucosidase-IN-104	Glycosidase	Metabolic Disease
α-Glucosidase-IN-104 (Compound 9s) is an efficient inhibitor of α-glucosidase with an IC₅₀ of 24.32 μM. α-Glucosidase-IN-104 has a weak inhibitory effect on α-amylase and avoids gastrointestinal side effects. α-Glucosidase-IN-104 can be used for research on type 2 diabetes .

HY-149973

α-Amylase-IN-4	Amylases	Metabolic Disease
α-Amylase-IN-4 (Compd 10y) show maximum inhibition of amylase activity with IC₅₀ value 17.83 ± 0.14 μg/mL .

HY-W112651

2,4,6-Triphenylaniline	Glycosidase Amylases	Metabolic Disease
2,4,6-Triphenylaniline has anti-diabetic activity and can be encapsulated in nano-emulsions (NE) to enhance stability and permeability. The NE loaded with 2,4,6-Triphenylaniline inhibits α-glucosidase and *α-amylase* .

HY-174319

α-Amylase/α-Glucosidase-IN-20	Amylases Glycosidase	Metabolic Disease
α-Amylase/α-Glucosidase-IN-20 (Compound 6b) is a dual inhibitor of *α-Amylase* and α-Glucosidase with IC₅₀s of 414.57 and 924.15 μM for α-Amylase and α-Glucosidase, respectively. α-Amylase/α-Glucosidase-IN-20 shows a potent anti-diabetic activity, promising for diabetes research .

HY-161355

α-Amylase/α-Glucosidase-IN-9	Amylases Glycosidase	Metabolic Disease
α-Amylase/α-Glucosidase-IN-9 (compound 5h) is a dual inhibitor for both *α-amylase* (IC₅₀ = 16.4 μM) and α-glucosidase (IC₅₀ = 31.6 μM) enzymes .

HY-149557

α-Amylase/α-Glucosidase-IN-5	Glycosidase Amylases	Metabolic Disease
α-Amylase/α-Glucosidase-IN-5 (compound 4l) is a dual inhibitor of α-glucosidase (Glucosidase) and α-amylase (Amylases) with IC₅₀s of 5.96 μM and 1.62 μM, respectively. α-Amylase/α-Glucosidase-IN-4 has potential antidiabetic activity .

HY-162673

α-Amylase/α-Glucosidase-IN-16	Amylases Glycosidase	Metabolic Disease
α-Amylase/α-Glucosidase-IN-16 (compound 15) is a potent dual inhibitor of *α-amylase* and α-Glucosidase with IC₅₀ values of 0.8 and 1.2 μM, respectively. α-Amylase/α-Glucosidase-IN-16 can be used in the study of diabetes mellitus (DM) .

HY-162169

α-Amylase/α-Glucosidase-IN-8	Amylases Glycosidase	Metabolic Disease
α-Amylase/α-Glucosidase-IN-8 (Compound 7p) is a potent dual inhibitor of *α-amylase* and α-glucosidase, with IC₅₀s of 10.19 and 10.33 μM, respectively. α-Amylase/α-Glucosidase-IN-8 has good anti-oxidant activity(IC₅₀ = 14.93 μM). α-Amylase/α-Glucosidase-IN-8 can be used for the research of diabetes .

HY-169737

Inulobiose	Glycosidase Amylases	Metabolic Disease
Inulobiose is a difructan disaccharide that can be isolated from Pistacia vera L.. Inulobiose inhibits α-glycosidase and *α-amylase* activities with IC₅₀s of 1.87 and 40.72 mg/mL, respectively. Inulobiose can be used for the research of diabetes and glomerular filtration rate testing .

HY-163439

α-Amylase/α-Glucosidase-IN-12	Amylases Glycosidase	Metabolic Disease
α-Amylase/α-Glucosidase-IN-12 (compound 10k) is a dual inhibitor targeting α-glucosidase and α-amylase with IC₅₀ of 34.52 nM and 24.62 nM, respectively. α-Amylase/α-Glucosidase-IN-12 is an inhibitor designed based on triazolo[4,3-b][1,2,4]triazine and has the potential to be used in diabetes research .

HY-N8134

2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one	Dipeptidyl Peptidase	Metabolic Disease
2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one is a natural product found in the leaves and stem bark of M. glabra. 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one displays binding affinities with dipeptidyl peptidase-4 (DPP-4) and *α-Amylase*. 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one has potential antidiabetic activities .

HY-157537

α-Amylase-IN-5	Amylases	Metabolic Disease
α-Amylase-IN-5 (compound 3a) is a *α-amylase* inhibitor, with an IC₅₀ of 18.8 mM .

HY-161782

α-Amylase-IN-7	Amylases	Metabolic Disease
α-Amylase-IN-7 (Compound 6e) is an inhibitor for *α-Amylase* with an IC₅₀ of 40 μM. α-Amylase-IN-7 exhibits potential as an antidiabetic agent .

Cat. No.	Product Name	Type

HY-W009694

3,5-Dinitrosalicylic acid	Biochemical Assay Reagents
3,5-Dinitrosalicylic acid the derivative of salicylic acid. 3,5-Dinitrosalicylic acid is used in the α-amylase assay, carbohydrase assay, and for the colorimetric determination of reducing substances .

HY-153102

G3-CNP	Biochemical Assay Reagents
G3-CNP is an α-amylase substrate. The absorbance of G3-CNP cleavage product 2-chloro-4-nitrophenol is measured at 405 nm, which can be used to detect enzyme activity .

HY-160113

Sodium phosphate buffer 0.02 M, pH 6.9

Biochemical Assay Reagents

Sodium phosphate buffer 0.02 M, pH 6.9 is a commonly used aqueous biological buffer that maintains a stable pH value. Sodium phosphate buffer 0.02 M, pH 6.9 is often used in enzyme activity assays, such as α-amylase assays. Sodium phosphate buffer 0.02 M, pH 6.9 is prepared by mixing disodium hydrogen phosphate (Na₂HPO₄) (HY-B2243) and sodium dihydrogen phosphate (NaH₂PO₄) (HY-Y0308) to a total concentration of 0.02 M .

HY-W005598

2-Hydroxyquinoline	Biochemical Assay Reagents
2-Hydroxyquinoline is an inhibitor of α-glucosidase and *α-amylase* with IC₅₀ values of 64.4 µg/mL and 130.5 µg/mL, respectively. 2-Hydroxyquinoline can be used in the study of diabetes .

HY-B2241A

Potassiumalum, for cell culture

Aluminum potassium sulfate dodecahydrate, for cell culture

Biochemical Assay Reagents

Potassiumalum, for cell culture (Aluminum potassium sulfate dodecahydrate, for cell culture) is an egg white adjuvant. Potassiumalum, for cell culture acts as a mordant to help dyes bind to tissue components, enhancing the staining effect and stability during staining. Potassiumalum, for cell culture can induce allergic reactions in mice. Potassium alum, for cell culture can be used in research for bacterial and tissue staining .

HY-N1731

2′-Hydroxy-5′-methoxyacetophenone

Biochemical Assay Reagents

2'-Hydroxy-5'-methoxyacetophenone is an acetophenone derivative with acaricidal activities. 2'-Hydroxy-5'-methoxyacetophenone attenuates the inﬂammatory response via NF-κB signaling pathway. 2'-Hydroxy-5'-methoxyacetophenone exhibits significant inhibitory activity against α-amylase, collagenase and aldose reductase (AR) with IC₅₀s of 0.928, 3.264 and 20.046 μM, highlighting its potential in combating diabetes. 2'-Hydroxy-5'-methoxyacetophenone exhibits anti-ovarian cancer activity .

HY-W008168

Quinoline-2-carboxaldehyde 2-Quinolinecarboxaldehyde	Biochemical Assay Reagents
Quinoline-2-carboxaldehyde (2-Quinolinecarboxaldehyde) is a quinoline derivative that serves as a synthetic precursor for Schiff base copper complexes. Quinoline-2-carboxaldehyde is applicable to research related to the synthetic design of biomaterials or organic compounds, such as fluorescent sensors .

HY-137228

4-Nitrophenylmaltohexaoside	Biochemical Assay Reagents
4-Nitrophenylmaltohexaoside is a chromogenic substrate targeting α-amylase.

HY-137785

2-Chloro-4-nitrophenyl-β-D-maltotrioside	Biochemical Assay Reagents
2-Chloro-4-nitrophenyl-β-D-maltotrioside is a chromogenic substrate used in bioluminescent and fluorescent assays to detect α-amylase.

Cat. No.	Product Name	Target	Research Area

HY-P2055

A-57696	Endogenous Metabolite	Endocrinology
A-57696 is a cholecystokinin antagonist with selective activity at cortical CCK-B receptors (IC50 = 25 nM). A-57696 behaves as a competitive antagonist in reversing CCK8-stimulated pancreatic alpha-amylase secretion and phosphatidylinositol degradation. A-57696 fails to induce gallbladder contraction and inhibits CCK8-induced contraction. A-57696 behaves as a partial agonist at CCK-B/gastrin receptors on NCI-H345 cells, achieving 80% of the maximal CCK8 response. A-57696 and CCK8 inhibit each other in a calcium mobilization assay .

Species:	Human (2) Rhesus Macaque (2)
Tag:	His (3) Fc (1)
Source:	HEK293 (4)

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HY-P76722

	AMY2A Protein, Human (HEK293, His) Pancreatic alpha-amylase; PA; 1,4-alpha-D-glucan glucanohydrolase	Human	HEK293
	AMY2A is a hydrolytic enzyme secreted by the pancreas that can hydrolyze α- 1,4-glycosidic bond, belonging to α- Members of the amylase family. AMY2A plays an important role in digesting dietary starch, and inhibiting AMY2A can lead to a decrease in postprandial blood glucose levels. Therefore, by regulating α- Amylase activity to control blood sugar level has therapeutic significance for diabetes, obesity and other diseases. AMY2A Protein, Human (HEK293, His) is the recombinant human-derived AMY2A protein, expressed by HEK293 , with C-His labeled tag.

HY-P76724

	AMY2A Protein, Rhesus Macaque (HEK293, His) Pancreatic alpha-amylase; PA; 1,4-alpha-D-glucan glucanohydrolase	Rhesus Macaque	HEK293
	AMY2B is a hydrolytic enzyme secreted by the pancreas that can hydrolyze α- 1,4-glycosidic bond, belonging to α- Members of the amylase family. AMY2B plays an important role in digesting dietary starch, and inhibiting AMY2B can lead to a decrease in postprandial blood sugar levels. Therefore, by regulating α- Amylase activity to control blood sugar level has therapeutic significance for diabetes, obesity and other diseases. AMY2A Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived AMY2A protein, expressed by HEK293 , with C-His labeled tag.

HY-P76723

	AMY2A Protein, Rhesus Macaque (HEK293, Fc) Pancreatic alpha-amylase; PA; 1,4-alpha-D-glucan glucanohydrolase	Rhesus Macaque	HEK293
	AMY2B is a hydrolytic enzyme secreted by the pancreas that can hydrolyze α- 1,4-glycosidic bond, belonging to α- Members of the amylase family. AMY2B plays an important role in digesting dietary starch, and inhibiting AMY2B can lead to a decrease in postprandial blood sugar levels. Therefore, by regulating α- Amylase activity to control blood sugar level has therapeutic significance for diabetes, obesity and other diseases. AMY2A Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived AMY2A protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P7500

	AMY2B Protein, Human (HEK293, His) rHuAlpha-amylase 2B, His; AMY2B; Alpha-amylase 2B	Human	HEK293
	AMY2B Protein, Human (HEK293, His) is produced by HEK293 cells. AMY2B is a type of human alpha-amylase.

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Host:	Mouse (2) Rabbit (1)
Reactivity:	Human (3) Rat (2)
Application:	WB (3) FC (2) ELISA (2)
Isotype:	IgG (1) IgG1 (2)
Conjugation:	Non-conjugated (3)
Clonality:	Monoclonal (1) Monoclonal Antibody (1) Recombinant (1)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P82813

	*Salivary alpha Amylase* Antibody (YA2558)** Alpha amylase; AMY1; AMY1C; AMY2; AMY2B; AMY3; HXA	WB	Human
	Salivary alpha Amylase Antibody (YA2558) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Salivary alpha Amylase.

HY-P84042

	*Salivary alpha Amylase* Antibody (YA3739)** AMY1	WB, FC, ELISA	Human, Rat
	Salivary alpha Amylase Antibody (YA3739) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Salivary alpha Amylase.

HY-P84042A

	*Salivary alpha Amylase* Antibody (YA3739)(PBS only)** AMY1	WB, FC, ELISA	Human, Rat
	Salivary alpha Amylase Antibody (YA3739) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Salivary alpha Amylase.

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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

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α-amylase

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