HPA-IN-1
HPA-IN-1 (Compound 1) is a potent and selective human pancreatic α-amylase (HPA) inhibitor with IC50 values of 12.0 μM and 410.4 μM against HPA and α-glucosidase, respectively.
For research use only. We do not sell to patients.
- Formula: C33H32N4O11
- Molecular Weight:660.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
IC50: 12.0 μM (HPA), 410.4 μM (α-glucosidase)[1]
In Vitro
HPA-IN-1 (Compound 1) has three hydrogen bonds interacting with HPA[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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Molecular Weight 660.63
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Formula C33H32N4O11
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SMILES
O=C(NCC1=CN(N=N1)CCCCCCOC2=C(OC3=C(C=C(C=C3C2=O)O)O)C4=CC(O)=C(C(O)=C4)O)/C=C/C5=CC=C(C(O)=C5)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HPA-IN-1 Related Classifications
HY-143268 Related Classifications
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