α-Glucosidase-IN-105
α-Glucosidase-IN-105 is a selective and potent α-Glucosidase inhibitor with an IC50 of 31.36 μM. α-Glucosidase-IN-105 also inhibits α-Amylase (IC50 = 104.2 μM). α-Glucosidase-IN-105 exhibits inhibitory effects comparable to the standard drug \rAcarbose (HY-B0089). α-Glucosidase-IN-105 can be used for the research of type 2 diabetes.
For research use only. We do not sell to patients.
- Formula: C84H62N12O4
- Molecular Weight:1303.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
α‑glucosidase 31.36 μM (IC50) |
α-Amylase 104.2 μM (IC50) |
In Vitro
α-Glucosidase-IN-105 (Compound 6c) demonstrates α-Amylase inhibition with an IC50 of 104.2 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 1303.47
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Formula C84H62N12O4
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SMILES
COC(C=C1)=CC=C1C2=NN(C3=CC=CC=C3)C=C2/C4=C5C=CC(/C(C6=CN(C7=CC=CC=C7)N=C6C8=CC=C(OC)C=C8)=C9C=C/C(N/9)=C(C(C=C/%10)=NC%10=C(C%11=CC=C4N%11)\C%12=CN(N=C%12C%13=CC=C(OC)C=C%13)C%14=CC=CC=C%14)\C%15=CN(N=C%15C%16=CC=C(OC)C=C%16)C%17=CC=CC=C%17)=N\5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)