α-Glucosidase-IN-105 

α-Glucosidase-IN-105 is a selective and potent α-Glucosidase inhibitor with an IC₅₀ of 31.36 μM. α-Glucosidase-IN-105 also inhibits α-Amylase (IC₅₀ = 104.2 μM). α-Glucosidase-IN-105 exhibits inhibitory effects comparable to the standard drug \rAcarbose (HY-B0089). α-Glucosidase-IN-105 can be used for the research of type 2 diabetes^[1].

α-Glucosidase-IN-105 (Compound 6c) demonstrates α-Amylase inhibition with an IC50 of 104.2 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

1303.47

C₈₄H₆₂N₁₂O₄

COC(C=C1)=CC=C1C2=NN(C3=CC=CC=C3)C=C2/C4=C5C=CC(/C(C6=CN(C7=CC=CC=C7)N=C6C8=CC=C(OC)C=C8)=C9C=C/C(N/9)=C(C(C=C/%10)=NC%10=C(C%11=CC=C4N%11)\C%12=CN(N=C%12C%13=CC=C(OC)C=C%13)C%14=CC=CC=C%14)\C%15=CN(N=C%15C%16=CC=C(OC)C=C%16)C%17=CC=CC=C%17)=N\5

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Peddakotla SVK, et al. Design, synthesis, α-glucosidase inhibitory activity, and molecular docking of novel pyrazolyl-porphyrin hybrids as potential antidiabetic agents. Bioorg Med Chem Lett. 2026;131:130462.  [Content Brief]