1. Metabolic Enzyme/Protease
  2. Glucosidase
  3. Diphlorethohydroxycarmalol

Diphlorethohydroxycarmalol 

Cat. No.: HY-N10413
Handling Instructions

Diphlorethohydroxycarmalol, a kind of phlorotannin, is an orally active α-glucosidase and α-amylase inhibitor with IC50s of 0.16 mM and 0.53 mM, respectively. Diphlorethohydroxycarmalol has anti-diabetic activities.

For research use only. We do not sell to patients.

Diphlorethohydroxycarmalol Chemical Structure

Diphlorethohydroxycarmalol Chemical Structure

CAS No. : 138529-04-1

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Description

Diphlorethohydroxycarmalol, a kind of phlorotannin, is an orally active α-glucosidase and α-amylase inhibitor with IC50s of 0.16 mM and 0.53 mM, respectively. Diphlorethohydroxycarmalol has anti-diabetic activities[1].

IC50 & Target

IC50: 0.16 mM (α-glucosidase) and 0.53 mM (α-amylase) [1]

In Vivo

The increase of postprandial blood glucose levels are significantly suppressed in the Diphlorethohydroxycarmalol-administered group than those in the streptozotocin-induced diabetic or normal mice. Moreover, the area under curve (AUC) is significantly reduced via Diphlorethohydroxycarmalol (100 mg/kg; p.o.) administration (2022 versus 2210 mmol x min/lL) in the diabetic mice as well as it delays absorption of dietary carbohydrates[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

512.38

Formula

C24H16O13

CAS No.
SMILES

OC1=CC(O)=C(OC2=C(O)C(O)=C3OC4=CC(O)=C(OC5=CC(O)=CC(O)=C5)C(O)=C4OC3=C2)C(O)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Diphlorethohydroxycarmalol
Cat. No.:
HY-N10413
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