2. Metabolic Enzyme/Protease
  3. Amylases Glucosidase
  4. Antidiabetic agent 5

Antidiabetic agent 5 (compound S1) is a antidiabetic agent. Antidiabetic agent 5 inhibits the activity of α-glucosidase and α-amylase with IC50 values of 3.91, 8.89 µM, respectively. Antidiabetic agent 5 decreases sugar levels. Antidiabetic agent 5 has the potential for the research of type-II diabetes.

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Antidiabetic agent 5 Chemical Structure

Antidiabetic agent 5 Chemical Structure

CAS No. : 2152667-21-3

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Description

Antidiabetic agent 5 (compound S1) is a antidiabetic agent. Antidiabetic agent 5 inhibits the activity of α-glucosidase and α-amylase with IC50 values of 3.91, 8.89 µM, respectively. Antidiabetic agent 5 decreases sugar levels. Antidiabetic agent 5 has the potential for the research of type-II diabetes[1].

IC50 & Target

IC50: 3.91 µM (α-glucosidase); 8.89 µM (α-amylase)[1]
In Vivo

Antidiabetic agent 5 (compound S1) 是一种抗糖尿病剂。Antidiabetic agent 5 抑制 α-葡萄糖苷酶 (α-glucosidase) 和 α-淀粉酶 (α-amylase) 的活性，IC50 值分别为3.91、8.89 μM。Antidiabetic agent 5 降低血糖水平。Antidiabetic agent 5 具有研究 II 型糖尿病的潜力[1]。

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 26-33 g, BALB/c mice (diabetes)[1]
Dosage: 3.9, 7.8 mg/kg
Administration:
Result: Exhibited a good biochemical profile with lower sugar level (110–115 mg/dL), increased insulin level (25–30 μM/L), and low level of cholesterol (85 mg/dL) and creatinine (0.6 mg/dL) in blood.
Molecular Weight

357.38

Formula

C17H15N3O4S
CAS No.
Unlabeled CAS

SMILES

OC1=C(C(N/N=C(C2=CC=CC=C2)\C)=O)NS(C3=CC=CC=C31)(=O)=O
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Purity & Documentation
References
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Antidiabetic agent 5 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antidiabetic agent 52152667-21-3Antidiabetic agent5Antidiabetic agent-5AmylasesGlucosidasetype-II diabetessugar levelinsulincreatinineInhibitorinhibitorinhibit

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