Antidiabetic agent 8
Antidiabetic agent 8 is an orally active multi-target inhibitor, with IC50 values of 9.79, 6.36 and 19.08 μM against α-glucosidase, α-amylase and PTP1B, respectively. Antidiabetic agent 8 reduces postprandial blood glucose elevation. Antidiabetic agent 8 can be used in the research of type 2 diabetes.
For research use only. We do not sell to patients.
- Formula: C23H18BrN3O3S
- Molecular Weight:496.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Antidiabetic agent 8 (compound 5l) shows low cytotoxicity against HEK-293 cells after 24 h, with an IC50 of 138.08 μM, which is much higher than its enzyme inhibitory concentration[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:KM mice (male, 8-week-old)[1]
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Dosage:20 mg/kg
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Administration:p.o.; single dose
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Result:Reduced the area under the blood glucose curve (AUC) by 12.08% relative to the control group.
Chemical Information
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Molecular Weight 496.38
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Formula C23H18BrN3O3S
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SMILES
OC(C=C1)=CC=C1C(O2)=NN=C2SCC(O)CN3C4=C(C=CC(Br)=C4)C5=C3C=CC=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antidiabetic agent 8 Related Classifications
HY-181683 Related Classifications
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