Quercetin 3-(6″-caffeoylsophoroside)
Quercetin 3-(6″-caffeoylsophoroside) is an orally active α-amylase inhibitor, with an IC50 of 73.66 μg/mL. Quercetin 3-(6″-caffeoylsophoroside) presents in thehydro-methanolic extract of Cardamine hirsuta Linn. Quercetin 3-(6″-caffeoylsophoroside) shows the antidiabetic activities by oxidative stress reduction and α-amylase inhibition. Quercetin 3-(6″-caffeoylsophoroside) can be used for diabetes mellitus research.
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- No. CAS: 1032595-77-9
- Fòrmula: C27H40N4O7
- Peso molecular:532.63
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
In Vivo
Quercetin 3-(6″-caffeoylsophoroside) (125, 250, 500 mg/kg, p.o.) improves type 2 diabetes mellitus of SD rats by oxidative stress reduction and α-amylase inhibition[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:FED HFD (45% fat) for 30 days to induce type 2 diabetes mellitus in SD rats[1]
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Dosage:125, 250, 500 mg/kg
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Administration:Oral gavage (p.o.)
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Result:Significantly decreased the blood glucose level, improved biochemical parameters as well as oxidative stress by reduction of lipid peroxidation, and increased high-density lipoproteins with dose of 500mg/kg.
Enhanced activities of glutathione-s-transferase, glutathione, superoxide dismutase.
Restored cellular architecture in the histopathological examination.
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Animal Model:Acute oral toxicity in 8-week male SD rats[1]
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Dosage:50, 100, 500, 1000, and 2000 mg/kg
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Administration:Oral gavage (p.o.)
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Result:Safe for use in anti-diabetic research.
Chemical Information
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No. CAS 1032595-77-9
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Peso molecular 532.63
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Fòrmula C27H40N4O7
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SMILES
O=C(CCC(N(C(C1=C(OC)C(OC)=CC=C1)C(NC(C)(C)C)=O)CCCOCC)=O)NC2=NOC(C)=C2
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Quercetin 3-(6″-caffeoylsophoroside) Related Classifications
HY-N11844 Related Classifications
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