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Cat. No.: HY-N10360

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Ellipyrone A

Name: Ellipyrone A
Brand: MedChemExpress
SKU: HY-N10360
Availability: PreOrder

Ellipyrone A, a γ-pyrone enclosed macrocyclic poyketide, shows inhibition potential against dipeptidyl peptidase-4 (IC₅₀=0.35 mM). Ellipyrone A also has anti-carbolytic property against α-glucosidase (IC₅₀=0.74 mM) and α-amylase (IC₅₀=0.59 mM).

For research use only. We do not sell to patients.

Formula: C₂₅H₃₄O₈

Molecular Weight:462.53

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Ellipyrone A Chemical Structure

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Data Download

Data Sheet (270 KB)

Handling Instructions (2659 KB)

To place orders, for customer services and technical support, please contact:

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Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec

Biological Activity

Chemical Information

Purity & Documentation

References

Help & FAQs

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

All Dipeptidyl Peptidase Isoforms
More

DPP-1

DPP-2

DPP-4

DPP-8

DPP-9

Biological Activity

Description

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Classifications

Bioz

Biological Activity

Description

Ellipyrone A, a γ-pyrone enclosed macrocyclic poyketide, shows inhibition potential against dipeptidyl peptidase-4 (IC₅₀=0.35 mM). Ellipyrone A also has anti-carbolytic property against α-glucosidase (IC₅₀=0.74 mM) and α-amylase (IC₅₀=0.59 mM)^[1].

All Dipeptidyl Peptidase Isoforms :

DPP-1

DPP-2

DPP-4

DPP-8

DPP-9

Chemical Information

Molecular Weight 462.53

Formula C₂₅H₃₄O₈

SMILES

C/C=C/CC1C(CC(CC(OC(CC(C/C=C/C2CC(C=C1O2)=O)OC(C)=O)CC)=O)O)=O

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Animals

marine cuttlefish, Sepia elliptica

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)

COA (2659 KB)

Elemental Analysis Report (2659 KB)

HNMR (2659 KB)

CNMR (2659 KB)

RP-HPLC (2659 KB)

NP-HPLC (2659 KB)

MS (2659 KB)

LCMS (2659 KB)

IR (2659 KB)

GC (2659 KB)

OR (2659 KB)

SDS-PAGE (2659 KB)

SEC-HPLC (2659 KB)

Other Report (2659 KB)

Handling Instructions (2659 KB)

References

[1]. Paulose, S.K., et al. Ellipyrones A-B, from oval bone cuttlefish Sepia elliptica: Antihyperglycemic γ-pyrone enclosed macrocyclic polyketides attenuate dipeptidyl peptidase-4 and carbolytic enzymes. Med Chem Res 31, 462–473 (2022).

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Ellipyrone A Related Classifications

HY-N10360 Related Classifications

Metabolic Enzyme/Protease

Dipeptidyl Peptidase

Disease Areas

Metabolic or Endocrine Disease

Natural Products

Disease Research Fields Animals Ketones, Aldehydes, Acids

Metabolic Disease

Metabolic Disease

Bioz

Powered by Bioz See more details on Bioz

Keywords

Ellipyrone A
Dipeptidyl Peptidase
macrocyclic poyketide
dipeptidyl peptidase-4
anti-carbolytic
α-glucosidase
α-amylase
Inhibitor
inhibitor
inhibit

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MCE Japan Authorized Agent:

ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社

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