155 Results for "

quencher

" in MedChemExpress (MCE) Product Catalog:
Products (155)

155 Results for "quencher" in MCE Product Catalog:

32
32 Publications Verification
Cat. No.: HY-K1042

MCE AntiFade Mounting Medium can slow the fluorescence quenching of various common fluorescent dyes with simple operation and good anti-fluorescence quenching effect.

loading...
    loading...
17
17 Cited Publications
Cat. No.: HY-126823
CAS No.: 234075-45-7
Purity:  95.33%
Synonyms: PGSK diacetate (5/6-mixture)
Target:  

Fluorescent Dye

Research Areas:  

Others

Phen green SK (PGSK) diacetate (PGSK diacetate (5/6-mixture)) is a metal ion-sensitive fluorescent probe that can penetrate cell membranes. Phen green SK (PGSK) diacetate can react with a variety of metal ions, including Fe 2+, Cd 2+, Co 2+, Ni 2+, Zn 2+, etc. Phen green SK (PGSK) diacetate chelates Fe 2+, resulting in fluorescence quenching, which can be restored when a membrane-permeable chelator is added, thereby reflecting the changes in the intracellular chelatable iron pool. The excitation/emission maxima of Phen green SK diacetate are 507/532 nm, respectively .
loading...
    loading...
15
15 Cited Publications
Cat. No.: HY-D0040
CAS No.: 1461-15-0
Synonyms: Fluorexon
Calcein is a fluorescent dye and self-quenching probe, used as an indicator of lipid vesicle leakage, and also as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium. Calcein cannot directly cross the intact cell membrane of a living cell, unlike Calcein-AM (HY-D0041) which is cell-permeable. Calcein can also be used as a model drug for evaluating efficiency and bioavailability of drug delivery systems .
loading...
    loading...
11
11 Cited Publications
Cat. No.: HY-W074143
CAS No.: 36309-88-3
Synonyms: [Ru(DPP)3]Cl2
Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride ([Ru(dpp)3] 2+) is an electrochemiluminescent (ECL) probe and oxygen-sensitive sensor. Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride can be used to modify electrode surfaces for the detection of sulfates (S2O8 2-) and oxalates, based on electrochemical reactions that generate excited-state species, releasing photons through irreversible redox reactions. Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride utilizes the oxygen quenching of fluorescence mechanism, where fluorescence intensity reflects the metabolic rate of living microorganisms or oxygen levels within cells/tumors, allowing for real-time detection. Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride's main applications include microbial detection, antibacterial activity studies, and tumor microenvironment research .
loading...
    loading...
9
9 Cited Publications
Cat. No.: HY-K1048

AntiFade Reagent (with DAPI) is used to slow the fluorescence quenching. The 5 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

loading...
    loading...
8
8 Cited Publications
Cat. No.: HY-D0720
CAS No.: 2315-97-1
Synonyms: NSC-151912; L-6868
Lucigenin is a chemiluminescence probe. Lucigenin can be used to detect the production of endogenous superoxide anion radical (O 2-). Lucigenin is extremely sensitive to chloride ions, while it combined with chloride ions, the fluorescence will be quenched. Lucigenin also can be used as a chloride indicator. Ex/Em=455/505 nm .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-D1080
CAS No.: 50402-56-7
Synonyms: 1,5-EDANS
EDANS (1,5-EDANS) is a novel and quenched fluorogenic substrate for assaying retroviral protease by resonance energy transfer (RET) .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P4931
CAS No.: 720710-69-0
Target:  

MMP

Research Areas:  

Cancer

Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a fluorescent peptide that is a quenched MMP peptide substrate. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 can be used for real-time quantification of MMP enzymatic activity. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is an elongated peptide of MMP substrate (FS-1) and is active against collagenases (MMP-1, MMP-8, MMP-13 ) and MT1-MMP with higher specificity constants than FS-1 . (Ex/Em=325 nm/400 nm)
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P2536
CAS No.: 305336-82-7
Research Areas:  

Others

Mca-Ala-Pro-Lys(Dnp)-OH, a specific ACE2 quenched fluorogenic substrate, can be used to detect ACE2 activity, such as urinary, heart and lung .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-15943
CAS No.: 91809-67-5
Synonyms: 6-Carboxytetramethylrhodamine
6-TAMRA (6-Carboxytetramethylrhodamine) is a fluorescent dye. 6-TAMRA is often used in combination with 6-FAM (HY-66021) as an acceptor or fluorescence quencher for fluorescence resonance energy transfer (FRET) in biochemical studies such as potassium ion detection and ribonuclease activity assays .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W127703
CAS No.: 65603-19-2
Octadecyl Rhodamine B chloride is an amphiphilic fluorescent probe with both membrane-binding ability and fluorescent properties, which easily forms aggregates in aqueous phase leading to self-quenching. Octadecyl Rhodamine B chloride can be used for cell membrane staining and further applied in membrane biology research. The maximum absorption/emission wavelengths of Octadecyl Rhodamine B chloride monomer in Triton X-100 are 565 nm/585 nm; the absorption peaks of aggregates in water are blue-shifted to 524 nm and 574 nm, with significantly quenched fluorescence .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W017604
CAS No.: 30418-59-8
Synonyms: m-Aminophenylboronic acid
Research Areas:  

Others

3-Aminophenylboronic acid (m-Aminophenylboronic acid) is a phenylboronic acid derivative. 3-Aminophenylboronic acid reacts covalently with cis-diol groups of glycoproteins, enabling selective capture and detection of glycoproteins through fluorescence quenching of APBA-functionalized copper nanoclusters .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-154834
CAS No.: 916753-61-2
Purity:  95.44%
Target:  

Fluorescent Dye

Research Areas:  

Others

BHQ-1 NHS is a quencher and fluorescent dye. BHQ-1 NHS enables direct labeling via fluorescently labeled nucleotides .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W000897
CAS No.: 206658-89-1
Research Areas:  

Others

3-Aminophenylboronic acid monohydrate is a phenylboronic acid derivative. 3-Aminophenylboronic acid monohydrate reacts covalently with cis-diol groups of glycoproteins, enabling selective capture and detection of glycoproteins through fluorescence quenching of APBA-functionalized copper nanoclusters .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-D1050
CAS No.: 82321-04-8
Synonyms: 6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester
DNP-X, SE (6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester), the DNP-X acid modified by succinimidyl ester, is an amine-reactive building block for developing a probe, which can be recognized by anti-DNP antibodies. DNP-X, SE (6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester) is also an excellent amine-reactive FRET quencher paired with Trp or Tyr.
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W127832
CAS No.: 123148-15-2
Ru(dpp)3(PF6)2 is a ruthenium (II) polypyridine complex and oxygen-sensing luminophore with excellent photostability and bright orange emission properties based on metal-to-ligand charge transfer (MLCT). Ru(dpp)3(PF6)2 undergoes oxygen-induced collisional luminescence quenching following the Stern-Volmer relationship, and can also engage in Förster-type resonance energy transfer with closed-form BTF6. Featuring excellent photophysical and electrochemical properties, Ru(dpp)3(PF6)2 is applied in studies on quenching-type oxygen sensors based on fluorinated ORMOSIL/xerogels and solid-state light-emitting devices .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W007671
CAS No.: 1080-06-4
H-Tyr-OMe is an amino acid derivative and also a coordinating ligand for Cu II ions. H-Tyr-OMe can serve as a surface functionalization reagent for carbon dots, and is used to prepare fluorescent probes for biothiol sensing. H-Tyr-OMe is oxidized to quinone under the catalysis of Tyrosinase via its phenolic hydroxyl group, which quenches the fluorescence of carbon dots. H-Tyr-OMe contains potential coordination sites, including carboxyl, amino and phenolic hydroxyl groups .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W012228
CAS No.: 3417-91-2
Research Areas:  

Others

H-Tyr-OMe.HCl is an amino acid derivative and also a coordinating ligand for Cu II ions. H-Tyr-OMe.HCl can serve as a surface functionalization reagent for carbon dots, and is used to prepare fluorescent probes for biothiol sensing. H-Tyr-OMe.HCl is oxidized to quinone under the catalysis of Tyrosinase via its phenolic hydroxyl group, which quenches the fluorescence of carbon dots. H-Tyr-OMe.HCl contains potential coordination sites, including carboxyl, amino and phenolic hydroxyl groups .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W127716
CAS No.: 136724-73-7
Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 is a potent ruthenium-based dye. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can bu used as an effective quencher of quantum dots (QDs) fluorescence and the capture probe of virus antigen EV71. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can be used sensitive electrogenerated chemiluminescence (ECL) labels for detection of matrix metalloproteinases (MMPs) .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-Y0678
CAS No.: 621-23-8
Synonyms: TRIMETHYL PHLOROGLUCINOL
1,3,5-Trimethoxybenzene (TRIMETHYL PHLOROGLUCINOL) is an electrophilic substitution reaction substrate targeting free chlorine (Cl +) and free bromine (Br +). 1,3,5-Trimethoxybenzene has highly selective electrophilic addition characteristics. By capturing halogens, it undergoes specific substitution reactions to generate stable halogenated products. 1,3,5-Trimethoxybenzene can not only quench residual oxidants, but also quantify the halogen concentration by detecting the product without affecting the stability of redox-sensitive disinfection byproducts (DBPs). 1,3,5-Trimethoxybenzene is mainly used in water quality testing and quantitative analysis of free chlorine/bromine in water. At the same time, in phytochemistry, it is a key component of rose fragrance and participates in the study of pollination attraction mechanism .
loading...
    loading...