Bis(4-nitrophenyl) phosphate
Based on 2 publication(s) in Google Scholar
Bis(4-nitrophenyl) phosphate (BNPP) is an esterase inhibitor, inhibits the activity of esterases such as carboxylesterase. Bis(4-nitrophenyl) phosphate inhibits the degradation of Abiraterone in fresh plasma. Bis(4-nitrophenyl) phosphate can be used as a substrate to determine the enzymatic activity of phosphodiesterase in the roots of wetland plants. Bis(4-nitrophenyl) phosphate also acts as a catalyst for metallomicelles and a catalyst that promotes ring-opening polymerization (ROP).
For research use only. We do not sell to patients.
- Purity: 99.93%
- CAS No.: 645-15-8
- Formula: C12H9N2O8P
- Molecular Weight:340.18
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) Bis(4-nitrophenyl) phosphate
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Biological Activity
Bis (4-nitrophenyl) phosphate (1-10 mM; 48 h-5 d) effectively stabilizes Abiraterone (HY-70013) in fresh human K2EDTA plasma at room temperature for at least 5 days[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 645-15-8
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Appearance Solid
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Molecular Weight 340.18
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Formula C12H9N2O8P
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Color Off-white to gray
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SMILES
O=P(OC1=CC=C([N+]([O-])=O)C=C1)(OC2=CC=C([N+]([O-])=O)C=C2)O
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Synonyms
BNPP
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
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Biomacromolecules
Trivalent GalNAc-Mediated Delivery of Cucurbitacin B Overcomes Systemic Toxicity for Potent HCC Chemoradiotherapy. [Abstract]2026 May 11;27(5):3080-3108. PMID: 41950466 -
Pharm Res
In vitro and ex vivo Pharmacological Profile of HY-022619, a Novel Intravenous P2Y12 Receptor Antagonist with Rapid-onset and Sustained Antiplatelet Activity. [Abstract]2026 May;43(5):1425-1440. PMID: 41951863
Purity & Documentation
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Data Sheet (271 KB)
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SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Bis(4-nitrophenyl)
- 645-15-8
- BNPP
- Phosphodiesterase (PDE)
- Carboxylesterase (CES)
- carboxylesterase
- metallomicelles
- arylacetamide deacetylase
- abiraterone
- p-nitrophenol
- esterase
- β-butyrolactone
- human K2EDTA plasma
- Cu(II) macrocyclic Schiff base complexes
- Ni(II) macrocyclic Schiff base complexes
- Inhibitor
- inhibitor
- inhibit