Bis(4-nitrophenyl) phosphate sodium
Based on 2 publication(s) in Google Scholar
Bis(4-nitrophenyl) phosphate sodium (BNPP sodium) is an esterase inhibitor, inhibits the activity of esterases such as carboxylesterase. Bis(4-nitrophenyl) phosphate sodium inhibits the degradation of Abiraterone in fresh plasma. Bis(4-nitrophenyl) phosphate sodium can be used as a substrate to determine the enzymatic activity of phosphodiesterase in the roots of wetland plants. Bis(4-nitrophenyl) phosphate sodium also acts as a catalyst for metallomicelles and a catalyst that promotes ring-opening polymerization (ROP).
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 4043-96-3
- Formula: C12H8N2NaO8P
- Molecular Weight:362.16
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Bis(4-nitrophenyl) phosphate sodium
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Biological Activity
Bis(4-nitrophenyl) phosphate (1-10 mM; 48 h-5 d) sodium effectively stabilizes Abiraterone (HY-70013) in fresh human K2EDTA plasma at room temperature for at least 5 days[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 4043-96-3
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Appearance Solid
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Molecular Weight 362.16
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Formula C12H8N2NaO8P
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Color White to yellow
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SMILES
O=P(OC1=CC=C([N+]([O-])=O)C=C1)(OC2=CC=C([N+]([O-])=O)C=C2)O[Na]
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Synonyms
BNPP sodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (2)
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Journal Impact Factor
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Most Recent
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Biomacromolecules
Trivalent GalNAc-Mediated Delivery of Cucurbitacin B Overcomes Systemic Toxicity for Potent HCC Chemoradiotherapy. [Abstract]2026 May 11;27(5):3080-3108. PMID: 41950466 -
Pharm Res
In vitro and ex vivo Pharmacological Profile of HY-022619, a Novel Intravenous P2Y12 Receptor Antagonist with Rapid-onset and Sustained Antiplatelet Activity. [Abstract]2026 May;43(5):1425-1440. PMID: 41951863
Solvent & Solubility
DMSO : 20 mg/mL (55.22 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7612 mL | 13.8061 mL | 27.6121 mL | 69.0303 mL |
| 5 mM | 0.5522 mL | 2.7612 mL | 5.5224 mL | 13.8061 mL | |
| 10 mM | 0.2761 mL | 1.3806 mL | 2.7612 mL | 6.9030 mL | |
| 15 mM | 0.1841 mL | 0.9204 mL | 1.8408 mL | 4.6020 mL | |
| 20 mM | 0.1381 mL | 0.6903 mL | 1.3806 mL | 3.4515 mL | |
| 25 mM | 0.1104 mL | 0.5522 mL | 1.1045 mL | 2.7612 mL | |
| 30 mM | 0.0920 mL | 0.4602 mL | 0.9204 mL | 2.3010 mL | |
| 40 mM | 0.0690 mL | 0.3452 mL | 0.6903 mL | 1.7258 mL | |
| 50 mM | 0.0552 mL | 0.2761 mL | 0.5522 mL | 1.3806 mL |
Bis(4-nitrophenyl) phosphate sodium Related Classifications
HY-W013205B Related Classifications
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- Bis(4-nitrophenyl) phosphate
- 4043-96-3
- BNPP
- Phosphodiesterase (PDE)
- Carboxylesterase (CES)
- carboxylesterase
- metallomicelles
- arylacetamide deacetylase
- abiraterone
- p-nitrophenol
- esterase
- β-butyrolactone
- human K2EDTA plasma
- Cu(II) macrocyclic Schiff base complexes
- Ni(II) macrocyclic Schiff base complexes
- Inhibitor
- inhibitor
- inhibit