6-Bromo-2-naphthol
Based on 1 Customer Validation
6-Bromo-2-naphthol is an RTP (real-time polymerase chain reaction) probe that forms a 1:1 or 2:1 complex with β-cyclodextrin (β-CD). 6-Bromo-2-naphthol is capable of real-time monitoring of PCR reactions and quantification of specific nucleic acid sequences. RTP probes are a class of small DNA or RNA sequences labeled with fluorescent dyes and quencher molecules, which can be widely used in gene expression analysis, SNP genotyping, and pathogen detection. 6-Bromo-2-naphthol embeds into the cyclodextrin cavity through hydrophobic interactions, inhibits the oxygen quenching effect, and emits a phosphorescent signal at room temperature. 6-Bromo-2-naphthol can also be used as an intermediate for the synthesis of antibacterial azo dyes, and its derivatives show antibacterial activity against Staphylococcus aureus, Escherichia coli and other bacteria.
For research use only. We do not sell to patients.
- Purity: 99.75%
- CAS No.: 15231-91-1
- Formula: C10H7BrO
- Molecular Weight:223.07
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
6-Bromo-2-naphthol forms a 1:1 complex with β-CD and emits phosphorescence in the presence of cyclohexane at room temperature with a detection limit of 0.04 μg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 15231-91-1
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Appearance Solid
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Molecular Weight 223.07
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Formula C10H7BrO
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Color White to off-white
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SMILES
BrC1=CC=C2C=C(O)C=CC2=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 200 mg/mL (896.58 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.4829 mL | 22.4146 mL | 44.8292 mL | 112.0729 mL |
| 5 mM | 0.8966 mL | 4.4829 mL | 8.9658 mL | 22.4146 mL | |
| 10 mM | 0.4483 mL | 2.2415 mL | 4.4829 mL | 11.2073 mL | |
| 15 mM | 0.2989 mL | 1.4943 mL | 2.9886 mL | 7.4715 mL | |
| 20 mM | 0.2241 mL | 1.1207 mL | 2.2415 mL | 5.6036 mL | |
| 25 mM | 0.1793 mL | 0.8966 mL | 1.7932 mL | 4.4829 mL | |
| 30 mM | 0.1494 mL | 0.7472 mL | 1.4943 mL | 3.7358 mL | |
| 40 mM | 0.1121 mL | 0.5604 mL | 1.1207 mL | 2.8018 mL | |
| 50 mM | 0.0897 mL | 0.4483 mL | 0.8966 mL | 2.2415 mL | |
| 60 mM | 0.0747 mL | 0.3736 mL | 0.7472 mL | 1.8679 mL | |
| 80 mM | 0.0560 mL | 0.2802 mL | 0.5604 mL | 1.4009 mL | |
| 100 mM | 0.0448 mL | 0.2241 mL | 0.4483 mL | 1.1207 mL |