15231-91-1
Chemical Structure
6-Bromo-2-naphthol
- CAS No.: 15231-91-1
- Formula:C10H7BrO
- Molecular Weight:223.07
IUPAC Name: 6-bromonaphthalen-2-ol
InChIKey: YLDFTMJPQJXGSS-UHFFFAOYSA-N
SMILES: BrC1=CC=C2C=C(O)C=CC2=C1
Biological Activity: 6-Bromo-2-naphthol is an RTP (real-time polymerase chain reaction) probe that forms a 1:1 or 2:1 complex with β-cyclodextrin (β-CD). 6-Bromo-2-naphthol is capable of real-time monitoring of PCR reactions and quantification of specific nucleic acid sequences. RTP probes are a class of small DNA or RNA sequences labeled with fluorescent dyes and quencher molecules, which can be widely used in gene expression analysis, SNP genotyping, and pathogen detection. 6-Bromo-2-naphthol embeds into the cyclodextrin cavity through hydrophobic interactions, inhibits the oxygen quenching effect, and emits a phosphorescent signal at room temperature. 6-Bromo-2-naphthol can also be used as an intermediate for the synthesis of antibacterial azo dyes, and its derivatives show antibacterial activity against Staphylococcus aureus, Escherichia coli and other bacteria[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
6-Bromo-2-naphthol | 99.75% | 6-Bromo-2-naphthol is an RTP (real-time polymerase chain reaction) probe that forms a 1:1 or 2:1 complex with β-cyclodextrin (β-CD). 6-Bromo-2-naphthol is capable of real-time monitoring of PCR reactions and quantification of specific nucleic acid sequences. RTP probes are a class of small DNA or RNA sequences labeled with fluorescent dyes and quencher molecules, which can be widely used in gene expression analysis, SNP genotyping, and pathogen detection. 6-Bromo-2-naphthol embeds into the cyclodextrin cavity through hydrophobic interactions, inhibits the oxygen quenching effect, and emits a phosphorescent signal at room temperature. 6-Bromo-2-naphthol can also be used as an intermediate for the synthesis of antibacterial azo dyes, and its derivatives show antibacterial activity against Staphylococcus aureus, Escherichia coli and other bacteria. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Escandar G M, et al. Room-temperature phosphorescence of 6-bromo-2-naphthol included in β-cyclodextrin in the presence of cyclohexane[J]. Talanta, 2001, 53(4): 851-856.
- [2]. Chopde H N, et al. Synthesis, characterization and antibacterial activity of some novel azo-azoimine dyes of 6-bromo-2-naphthol. Int. J. Chem. Tech. Res, 2010, 2(3): 1823-830.
- [3]. Muñoz de la Peña A, et al. Optimization of the room-temperature phosphorescence of the 6-bromo-2-naphthol-alpha-cyclodextrin system in aqueous solution. Talanta. 2000 Apr 28;51(5):949-55. [Content Brief]
Keywords
