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Cat. No.: HY-P11652

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Cardiogen

Cardiogen is a short biologically active peptide (Ala-Glu-Asp-Arg) that does not bind single-stranded deoxyribooligonucleotides, slightly quenches fluorescence of some double-stranded deoxyribooligonucleotides, strongly quenches fluorescence of methylated and unmethylated λ phage DNA-ethidium bromide complexes.

For research use only. We do not sell to patients.

CAS No.: 857267-11-9
Formula: C₁₈H₃₁N₇O₉
Molecular Weight:489.48

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Cardiogen Chemical Structure

CAS No.: 857267-11-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

Cardiogen does not bind with single-stranded monotonous oligonucleotides or GC-enriched oligonucleotides and only slightly interacts with one double-stranded oligonucleotide (FAM-GCG GCG TGATCA GCG GCG) with a Stern-Volmer constant of 0.34 × 10⁴^[1].
Cardiogen interacts with both unmethylated and methylated λ phage DNA-EB complexes more strongly than other tested peptides, with Stern-Volmer constants of 3.0 × 10⁴ (unmethylated) and 2.8 × 10⁴ (methylated)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 857267-11-9
Molecular Weight 489.48
Formula C₁₈H₃₁N₇O₉
Sequence

Ala-Glu-Asp-Arg
Sequence Shortening

AEDR
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Fedoreyeva LI, et al. Penetration of short fluorescence-labeled peptides into the nucleus in HeLa cells and in vitro specific interaction of the peptides with deoxyribooligonucleotides and DNA. Biochemistry (Mosc). 2011;76(11):1210-1219. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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