Dabcyl acid sodium
Dabcyl acid sodium (DABCYL sodium) is a nonfluorescent chromophore and a quencher. Dabcyl acid sodium can be used as molecular beacon nucleic acid probes to recognize and report the presence of specific nucleic acids in homogeneous solutions.
For research use only. We do not sell to patients.
- CAS No.: 845-46-5
- Formula: C15H14N3NaO2
- Molecular Weight:291.28
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Dabcyl acid sodium is paired with fluorophores (such as EDANS) for fluorescence resonance energy transfer (FRET). When the fluorophore (such as EDANS) and Dabcyl acid sodium are close to each other, the fluorescence of the fluorophore will be quenched by Dabcyl acid sodium. When the molecular beacon binds to the target nucleic acid, the fluorophore and the quencher are separated, and the fluorophore emits fluorescence, thereby realizing the detection of the target nucleic acid[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 845-46-5
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Molecular Weight 291.28
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Formula C15H14N3NaO2
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SMILES
O=C(C1=CC=C(C=C1)/N=N/C2=CC=C(N(C)C)C=C2)O[Na]
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Synonyms
DABCYL sodium; Para-methyl red sodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)