Aza-CyBz
Based on 1 Customer Validation
Aza-CyBz is a NaCl-responsive near-infrared heptamethine cyanine fluorescent probe. Aza-CyBz has an excitation wavelength of 740 nm and detects signals in the range of 760-900 nm. NaCl induces Aza-CyBz to form ordered aggregates, resulting in fluorescence quenching. Aza-CyBz shows no obvious response to interfering substances such as plant carbohydrates, hormones, PEG and ROS. Aza-CyBz can enter plant mitochondria and reflect changes in their salt concentration, and can be used for visual imaging of salt stress in Arabidopsis thaliana root tips and living plants.
For research use only. We do not sell to patients.
- Purity: 95.21%
- Formula: C43H49ClIN3O2
- Molecular Weight:802.23
-
Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
Aza-CyBz (10 μM) exhibits a sensitive and selective fluorescent response to Na+Cl− in cell-free solution, with a limit of detection of 170 μM. Na+Cl− induces the formation of J-aggregates, which quenches the fluorescence of monomers[1].
Aza-CyBz (10 μM; 1 h) enables visualization of salt stress in Arabidopsis thaliana root tips, with its fluorescence intensity decreasing as NaCl concentration increases; mitochondrial colocalization experiments demonstrate that this probe can enter mitochondria and reflect changes in salt concentration within them[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Appearance Solid
-
Molecular Weight 802.23
-
Formula C43H49ClIN3O2
-
SMILES
ClC1=C(/C=C/C2=[N+](CCC)C(C=CC=C3)=C3C2(C)C)CN(C(OCC4=CC=CC=C4)=O)C/C1=C\C=C5C(C)(C)C(C=CC=C6)=C6N/5CCC.[I-]
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Purity & Documentation
-
Data Sheet (271 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)