Aza-CyBz
Based on 1 Customer Validation
Aza-CyBz is a NaCl-responsive near-infrared heptamethine cyanine fluorescent probe. Aza-CyBz has an excitation wavelength of 740 nm and detects signals in the range of 760-900 nm. NaCl induces Aza-CyBz to form ordered aggregates, resulting in fluorescence quenching. Aza-CyBz shows no obvious response to interfering substances such as plant carbohydrates, hormones, PEG and ROS. Aza-CyBz can enter plant mitochondria and reflect changes in their salt concentration, and can be used for visual imaging of salt stress in Arabidopsis thaliana root tips and living plants.
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- Pureza: 95.21%
- Fòrmula: C43H49ClIN3O2
- Peso molecular:802.23
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Almacenamiento:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Actividad biológica
Aza-CyBz (10 μM) exhibits a sensitive and selective fluorescent response to Na+Cl− in cell-free solution, with a limit of detection of 170 μM. Na+Cl− induces the formation of J-aggregates, which quenches the fluorescence of monomers[1].
Aza-CyBz (10 μM; 1 h) enables visualization of salt stress in Arabidopsis thaliana root tips, with its fluorescence intensity decreasing as NaCl concentration increases; mitochondrial colocalization experiments demonstrate that this probe can enter mitochondria and reflect changes in salt concentration within them[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Peso molecular 802.23
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Fòrmula C43H49ClIN3O2
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SMILES
ClC1=C(/C=C/C2=[N+](CCC)C(C=CC=C3)=C3C2(C)C)CN(C(OCC4=CC=CC=C4)=O)C/C1=C\C=C5C(C)(C)C(C=CC=C6)=C6N/5CCC.[I-]
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Pureza y Documentación
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Ficha de datos (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)