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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
111 Results for "
Candida albicans infection
" in MedChemExpress (MCE) Product Catalog:
Products (111)
111 Results for "Candida albicans infection" in MCE Product Catalog:
2
Butoconazole nitrate (RS 35887), an imidazole antifungal agent, is active against Candida spp. and effective against vaginal infections due to Candida albicans. Butoconazole nitrate is presumed to function as other imidazole derivatives via inhibition of steroid synthesis .
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2 Cited Publications
Cat. No.: HY-B0293A
CAS No.: 64872-76-0
Butoconazole, an imidazole antifungal agent, is active against Candida spp. and effective against vaginal infections due to Candida albicans. Butoconazole is presumed to function as other imidazole derivatives via inhibition of steroid synthesis .
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1
1 Cited Publications
Cat. No.: HY-N3307
CAS No.: 40957-99-1
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1 Cited Publications
Cat. No.: HY-N6924
CAS No.: 80930-74-1
Category:
Infection Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Panax japonicas C. A. Mey. Metabolic Disease Plants Disease Research Fields Araliaceae Saccharides
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Cat. No.: HY-P10408
CAS No.: 1906866-53-2
Research Areas:
Synonyms: BAY-W-6341
Abafungin (BAY-W-6341) is a broad-spectrum fungicidal arylguanidine compound and a selective inhibitor of sterol-C-24-methyltransferase. Abafungin blocks the transmethylation reaction at the C-24 position of the sterol side chain during the ergosterol biosynthesis pathway. Abafungin directly disrupts fungal cell membrane integrity, and diminishes fungal viability independent of the fungal growth state. Abafungin can be applied to the research of fungal infections, particularly dermatomycoses .
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T-2307 is an antifungal agent with blood-brain barrier penetration. T-2307 exhibits broad-spectrum antifungal activity against Candida species, including echinocandin-resistant strains, Cryptococcus neoformans, Cryptococcus gattii, and some Aspergillus species. T-2307 selectively targets fungal mitochondrial respiratory chain complexes III and IV, causing collapse of the fungal mitochondrial membrane potential and exerting fungicidal or fungistatic effects. T-2307 can be used in research related to fungal infections such as invasive candidiasis, cryptococcosis, and aspergillosis .
Cat. No.: HY-P2124
CAS No.: 20829-55-4
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Quinalizarin is a protein kinase CK2 inhibitor with a Ki of 0.052 μM. Quinalizarin exhibits antifungal and anticancer activities. Quinalizarin induces ROS production, apoptotic signaling, mitochondrial pathway activation, cell cycle arrest, and cytotoxicity in cancer cells. Quinalizarin inhibits hyphal growth, biofilm formation, and mature biofilm integrity of Candida albicans. Quinalizarin can be used in research related to cancer and fungal infections .
Cat. No.: HY-W002016
CAS No.: 253-52-1
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Research Areas:
Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology Cancer
Phthalazine is a chemical scaffold. Phthalazine derivatives act as VEGFR-2 inhibitors, PARP-1 inhibitors, and anticancer agents. The complex of phthalazine with silver exhibits broad-spectrum antibacterial and antifungal activities against Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa PAO1, and Candida albicans. Phthalazine derivatives possess potent vasodilatory activity. Phthalazine can be used in research related to colon adenocarcinoma, breast cancer, hypertension, diabetes, and microbial infections .
Cat. No.: HY-N1341
CAS No.: 54835-70-0
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Roseoside is an inhibitor of DNA gyrase and HAV 3C protease, and also inhibits HCV NS5A/B replicase in human systems with an IC50 of 20 μM. Roseoside binds to the active site of enzymes and stabilizes the interaction by forming hydrogen bonds with key amino acid residues. Roseoside inhibits the growth of Gram-positive bacteria, Gram-negative bacteria, and Candida albicans, and interferes with HCV RNA replication in vitro by inhibiting HCV NS5A/B replicase (IC50=20 μM). Roseoside shows no cytotoxicity and serves as a research tool for studies related to bacterial infections, candidiasis, HAV and HCV .
Cat. No.: HY-W019929
CAS No.: 7783-90-6
Synonyms: Silver(Ⅰ) Chloride
Silver chloride (Silver (Ⅰ) Chloride) is an inorganic salt with antibacterial activity and the property of regulating alcohol oxidase. Silver chloride destabilizes alcohol oxidase and reduces its activity over time. Silver chloride exhibits antibacterial activity against human pathogenic Escherichia coli and Candida albicans. Silver chloride can be used in studies related to bacterial infections and fungal infections .
Cat. No.: HY-N2198
CAS No.: 22136-74-9
Category:
Flavonoids Guttiferae Phenols Polyphenols Plants Garcinia subelliptica Disease Research Fields Biflavones Cancer
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Tetraethylenepentamine pentahydrochloride is an orally active copper chelator and copper mobilizer. Tetraethylenepentamine pentahydrochloride exhibits growth inhibitory and hypolipidemic properties. Tetraethylenepentamine pentahydrochloride significantly increases urinary copper excretion and reduces renal copper accumulation in copper overload models, but does not significantly alter hepatic copper levels. Tetraethylenepentamine pentahydrochloride exerts growth inhibitory effects on Candida albicans and Fluconazole (HY-B0101)-resistant strains, and can be widely used in studies related to Wilson's disease and Candida infections .
Cat. No.: HY-136461
CAS No.: 22976-86-9
Synonyms: Polyoxorim
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Polyoxin D (Polyoxorim) is an Antifungal Antibiotic. Polyoxin D inhibits Chitin synthase with an I50 of 1 mM for Stomoxys calcitrans chitin synthase. Polyoxin D causes swelling and rupture of fungal hyphal tips and budding yeast cells, haustorial encasement, haustorial wall thickening, widening of the extrahaustorial matrix, and cytoplasmic vesicles and tubular structures. Polyoxin D causes swelling of filamentous chains in Candida albicans and morphological changes in Agaricus bisporus and Coprinus cinereus. Polyoxin D is used in research on bean rust and Candida albicans infections .
Cat. No.: HY-W357140
CAS No.: 18997-54-1
Synonyms: Phenylethyl β-D-glucopyranoside
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Cat. No.: HY-N12717
CAS No.: 79786-01-9
Cat. No.: HY-N3968
CAS No.: 17303-67-2
Synonyms: GTN; (R)-(+)-Goniothalamin
Category:
Cat. No.: HY-W014665
CAS No.: 4702-13-0
Synonyms: Phthaloyl glycine
N-Phthaloylglycine (Phthaloyl glycine) is a Type II fragmentary hapten (FX-type) with antimicrobial activity. N-Phthaloylglycine acts against Candida albicans, Escherichia coli, and Staphylococcus epidermidis. N-Phthaloylglycine can be used for the research of fungal and bacterial infection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
