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Results for "

anti-mycobacterial

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (28) AP-1 (1) Apoptosis (9) Autophagy (2) Bacterial (120) Bcl-2 Family (1) Biochemical Assay Reagents (1) Carbonic Anhydrase (1) Caspase (1) DNA/RNA Synthesis (6) Drug Derivative (1) Drug Intermediate (2) Drug Metabolite (1) Endogenous Metabolite (3) Fungal (4) Herbicide (2) HIV (1) HSP (1) Insecticide (1) Interleukin Related (4) Isotope-Labeled Compounds (9) Mitochondrial Metabolism (1) Monoamine Oxidase (1) Oxidative Phosphorylation (1) p38 MAPK (1) Parasite (16) PARP (1) Photosystem II (2) Potassium Channel (1) Reactive Oxygen Species (ROS) (6) Reference Standards (7) TNF Receptor (3)
By Research Areas:	Cancer (13) Cardiovascular Disease (3) Infection (126) Inflammation/Immunology (26) Metabolic Disease (3) Neurological Disease (1)

By Targets:

Antibiotic (28)

AP-1 (1)

Apoptosis (9)

Autophagy (2)

Bacterial (120)

Bcl-2 Family (1)

Biochemical Assay Reagents (1)

Carbonic Anhydrase (1)

Caspase (1)

DNA/RNA Synthesis (6)

Drug Derivative (1)

Drug Intermediate (2)

Drug Metabolite (1)

Endogenous Metabolite (3)

Fungal (4)

Herbicide (2)

HIV (1)

HSP (1)

Insecticide (1)

Interleukin Related (4)

Isotope-Labeled Compounds (9)

Mitochondrial Metabolism (1)

Monoamine Oxidase (1)

Oxidative Phosphorylation (1)

p38 MAPK (1)

Parasite (16)

PARP (1)

Photosystem II (2)

Potassium Channel (1)

Reactive Oxygen Species (ROS) (6)

Reference Standards (7)

TNF Receptor (3)

By Research Areas:

Cancer (13)

Cardiovascular Disease (3)

Infection (126)

Inflammation/Immunology (26)

Metabolic Disease (3)

Neurological Disease (1)

134

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1046

Clofazimine 10+ Cited Publications	Bacterial Antibiotic DNA/RNA Synthesis Interleukin Related Apoptosis	Infection Inflammation/Immunology Cancer
Clofazimine is an orally-active anti-mycobacterial agent with a wide range of anti-mycobacterial activity including leprosy and tuberculosis. Clofazimine exerts anti-inflammatory activities and anti-tumor activities by interfering DNA replication and inhibiting IL2 (IC₅₀ = 1.10 ± 0.26 μM, Jurkat T) production. Clofazimine can be used in mycobacterial and cancer research .

HY-17025

Rifabutin 5+ Cited Publications Ansamycin; LM-427	DNA/RNA Synthesis Bacterial Antibiotic	Infection
Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.

HY-B0535A

Ethambutol dihydrochloride 4 Publications Verification Emb dihydrochloride	Bacterial Antibiotic	Infection
Ethambutol dihydrochloride is an antimycobacterial compound that prevents cell wall formation by inhibiting arabinosyltransferase activity. Ethambutol dihydrochloride can be used to establish animal models of hyperuricemia and optic neuropathy.

HY-W012875

3-Nitropropanoic acid 4 Publications Verification β-Nitropropionic acid; Bovinocidin	Bacterial Apoptosis Autophagy	Infection Metabolic Disease Inflammation/Immunology
3-Nitropropanoic acid (β-Nitropropionic acid) is an irreversible and orally active inhibitor of succinate dehydrogenase. 3-Nitropropanoic acid exhibits potent antimycobacterial activity with a MIC value of 3.3 μM. 3-Nitropropanoic acid can induce cell apoptosis .

HY-B0535

Ethambutol 4 Publications Verification	Bacterial Antibiotic	Infection
Ethambutol is an antimycobacterial compound that prevents cell wall formation by inhibiting arabinosyltransferase activity. Ethambutol can be used to establish animal models of hyperuricemia and optic neuropathy.

HY-B0688

Dapsone 4 Publications Verification 4,4′-Diaminodiphenyl sulfone; DDS	Antibiotic Parasite Bacterial Reactive Oxygen Species (ROS)	Infection Inflammation/Immunology
Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities . Dapsone?exerts effective antileprosy activity?and inhibits folate synthesis in cell extracts of?M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

HY-N7030

5,7,3',4'-Tetramethoxyflavone 2 Publications Verification	Fungal Parasite Bacterial	Infection
5,7,3',4'-Tetramethoxyflavone, an orally active polymethoxyflavones (PMFs) that can be isolated from M. exotica, possesses various bioactivities, including anti-fungal, anti-malarial, anti-mycobacterial, and anti-inflammatory activities. 5,7,3',4'-Tetramethoxyflavone exhibits chondroprotective activity by targeting β-catenin signaling .

HY-N3845

Ergosterol peroxide 1 Publications Verification	Bacterial	Inflammation/Immunology Cancer
Ergosterol peroxide is a steroid derivative and can be isolated from a variety of fungi, yeast, lichens or sponges. Ergosterol peroxide has anti-tumour, proapoptotic, anti-inflammatory, anti-mycobacterial, and anti-proliferative activities .

HY-W013040

Pyrazine 1,4-Diazine	Drug Intermediate	Cardiovascular Disease Infection Inflammation/Immunology Cancer
Pyrazine (1,4-Diazine) is an aromatic nitrogen-containing heterocyclic compound with two nitrogen atoms, and is well known for its electron-deficient property. Pyrazine serves as a key pharmacophore in a variety of drugs, and also acts as the core skeleton of derivatives with anticancer, antimycobacterial, antithrombotic and anti-inflammatory activities .

HY-100725

BM212 4 Publications Verification	Bacterial	Infection
BM212 is a potent Mycobacterial membrane protein Large 3 (MmpL3) inhibitor. BM212 has strong bactericidal activity against both M. tuberculosis and some nontuberculosis mycobacteria. BM212 exhibits antimycobacterial activity against M. tuberculosis H37Rv with an MIC of 5 µM .

HY-N1976

(+)-(3R,8S)-Falcarindiol 1 Publications Verification (3R,8S)-Falcarindiol; 3(R),8(S),9(Z)-Falcarindiol		Infection Cancer
(+)-(3R,8S)-Falcarindiol ((3R,8S)-Falcarindiol; 3 (R),8 (S),9 (Z)-Falcarindiol) is an orally active polyacetylene anti-mycobacterial agent. (+)-(3R,8S)-Falcarindiol exhibits antibacterial activity against Gram-positive bacteria, Gram-negative bacteria and mycobacteria. Co-administration of (+)-(3R,8S)-Falcarindiol with (3R)-falcarinol alters the composition of gut microbiota, reduces colonic tumor lesions and slows down polyp growth. (+)-(3R,8S)-Falcarindiol can be used in research related to tuberculosis and colorectal cancer .

HY-17025S

Rifabutin-d7 Ansamycin-d₇; LM-427-d₇	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Rifabutin-d₇ is the deuterium labeled Rifabutin. Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.

HY-N1205

Spathulenol	Others	Cancer
Spathulenol is isolated from Aristolochia yunnanensis, and has antioxidant, anti-inflammatory, antiproliferative and antimycobacterial activities. Spathulenol shows a high antioxidant activity with an IC₅₀ of 85.60 μg/mL in the DPPH system ^[1].

HY-W506116

Ostruthin Ostruthine	Bacterial DNA/RNA Synthesis	Cardiovascular Disease Infection
Ostruthin is a natural coumarin compound with *bacterial* and antimycobacterial activities . Ostruthin inhibits the growth of mycobacteria and Staphylococcus aureus. Ostruthin suppresses vascular smooth muscle cell proliferation as well as de novo cellular DNA synthesis. Ostruthin is applicable to research related to mycobacterial infections and cardiovascular and cerebrovascular diseases .

HY-109588

NITD-349 1 Publications Verification	Bacterial	Infection
NITD-349 is an MmpL3 inhibitor that shows highly potent anti-mycobacterial activity with MIC₅₀ of 23 nM against virulent Mycobacterium tuberculosis H37Rv.

HY-109587

BM635	Bacterial	Infection
BM635 is a MmpL3 inhibitor with outstanding anti-mycobacterial activity. BM635 has an MIC₅₀ of 0.12 μM against M. tuberculosis H37Rv.

HY-129605

Ferulenol	Oxidative Phosphorylation Mitochondrial Metabolism	Infection
Ferulenol, a sesquiterpene prenylated coumarin derivative, specifically inhibits succinate ubiquinone reductase at the level of the ubiquinonecycle. Ferulenol shows good antimycobacterial activity and haemorrhagic action .

HY-N2060

Evocarpine	Apoptosis Bacterial	Infection Inflammation/Immunology Cancer
Evocarpine, a quinolone alkaloid that could be isolated from Evodiae fructus, inhibitss Ca ²⁺ influx through voltage-dependent calcium channels. Antimycobacterial activity .

HY-17025R

Rifabutin (Standard) Ansamycin (Standard); LM-427 (Standard)	Reference Standards Bacterial Antibiotic	Infection
Rifabutin (Standard) is the analytical standard of Rifabutin. This product is intended for research and analytical applications. Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.

HY-141715

BRD-8000.3	Antibiotic	Infection
BRD-8000.3, as a specific EfpA inhibitor, is a narrow-spectrum, bactericidal antimycobacterial agent with good wild-type activity. BRD-8000.3 can be used for the research of tuberculosis .

HY-153351

IpOHA	Bacterial	Infection
IpOHA is a potent plant KARI inhibitor. IpOHA also is an antimycobacterial agent with a K_i value of 97.7 nM for Mycobacterium tuberculosis (Mt) .

HY-162836

Rifamycin B 4-O-(Carboxymethyl)-Rifamycin	Antibiotic Bacterial	Infection
Rifamycin B (4-O-(Carboxymethyl)-Rifamycin) is a member of ansamycin antibiotics family with an anti-mycobacterial activity against tuberculosis, leprosy and AIDS-related mycobacterial infections. Rifamycin B is a metabolic product of Nocardia inediterranei, which can yield Rifamycin O and Rifamycin S (HY-125365) by microbial transformation .

HY-B0535S

Ethambutol-d4 Emb-d₄	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Ethambutol-d₄ is the deuterium labeled Ethambutol. Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.

HY-B1046S

Clofazimine-d7	Bacterial Antibiotic	Inflammation/Immunology
Clofazimine-d₇ is deuterium labeled Clofazimine. Clofazimine is an iminophenazine dye, has a marked anti-inflammatory effect, has been used in combination with other antimycobacterial agents to treat AIDS and Crohn's disease.

HY-146158

Fudapirine WX-081	Bacterial Potassium Channel Antibiotic	Infection
Fudapirine, an anti-tuberculosis agent, displays excellent anti-mycobacterial activity against M. tuberculosis H37Rv and low cytotoxicity. Fudapirine exhibits potent activity with MIC50s of 0.083 and 0.11 μg/mL for agent susceptible tuberculosis (DS-TB) and multidrug resistant tuberculosis (MDR-TB) strains. Fudapirine also inhibits hERG channel with the IC50 of 1.89 μM.

HY-P2064

Lariatin A	Bacterial	Infection
Lariatins is a novel anti-mycobacterial peptides with a lasso structure produced by Rhodococcus jostii K01-B0171 .

HY-N8131

Pangelin	Bacterial	Infection Cancer
Pangelin is a coumarin that can be found in Ducrosia anethifolia. Pangelin exhibits anti-mycobacterial and anti-tumor activities .

HY-15993

Posizolid AZD2563; AZD5847	Antibiotic	Infection
Posizolid (AZD2563), an oxazolidinone antibiotic, is developed by AstraZeneca for the study of bacterial infections. Posizolid shows very good *anti-mycobacterial* activity .

HY-G0016

N-Acetyl dapsone MADDS; Monoacetyldapsone	Drug Metabolite	Others
N-Acetyl dapsone (MADDS) is the major metabolite of Dapsone (HY-B0688). Dapsone is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities .

HY-133671S

Monooctyl phthalate-d4 Mono-n-octyl phthalate-d₄	Isotope-Labeled Compounds Bacterial	Infection
Monooctyl phthalate-d₄ (Mono-n-octyl phthalate-d₄) is a deuterium labeled Monooctyl phthalate (HY-133671). Monooctyl phthalate (Mono-n-octyl phthalate) exhibits antimycobacterial activity with a MIC of 20 μg/mL .

HY-N2277

3β,7β,15β-Trihydroxy-11-oxo-lanosta-8-en-24→20 lactone	Bacterial	Infection Inflammation/Immunology
3β,7β,15β-Trihydroxy-11-oxo-lanosta-8-en-24→20 lactone is a natural compound that could be isolated from G. lucidum with antimycobacterial activity.

HY-W013040S

Pyrazine-d4 1,4-Diazine-d₄	Endogenous Metabolite	Others
Pyrazine-d₄ is the deuterium labeled Pyrazine . Pyrazine is an aromatic nitrogen-containing heterocyclic compound with two nitrogen atoms, and is well known for its electron-deficient property. Pyrazine serves as a key pharmacophore in a variety of drugs, and also acts as the core skeleton of derivatives with anticancer, antimycobacterial, antithrombotic and anti-inflammatory activities.

HY-151204

PknB-IN-1	Bacterial	Infection Inflammation/Immunology
PknB-IN-1 (Compound 2) is a protein kinase B (PknB) inhibitor (IC₅₀=14.4 μM). PknB-IN-1 shows anti-mycobacterial activity, can inhibit M. tuberculosis H37Rv strain growth (MIC=6.2 μg/mL) .

HY-B1046R

Clofazimine (Standard)	Reference Standards Bacterial Antibiotic DNA/RNA Synthesis Interleukin Related Apoptosis	Infection Inflammation/Immunology Cancer
Clofazimine (Standard) is the analytical standard of Clofazimine. This product is intended for research and analytical applications. Clofazimine is an orally-active anti-mycobacterial agent with a wide range of anti-mycobacterial activity including leprosy and tuberculosis. Clofazimine exerts anti-inflammatory activities and anti-tumor activities by interfering DNA replication and inhibiting IL2 (IC₅₀ = 1.10 ± 0.26 μM, Jurkat T) production. Clofazimine can be used in mycobacterial and cancer research .

HY-N9947

Methyl-6-gingerol	Bacterial Antibiotic	Infection
Methyl-6-gingerol is an antimicrobial agent derived from Aframomum melegueta that exhibits anti-mycobacterial activity by inhibiting the efflux of toxins within Mycobacterium species .

HY-N13075

Mycoplanecin A	Antibiotic Bacterial	Infection
Mycoplanecin A is a cyclic peptide antibiotic. Mycoplanecin A has strong anti-mycobacterial, luteus, and Hypococcus activity. Mycoplanecin A also has moderate anti-Xanthomonas oryzae activity. Mycoplanecin A also has antibacterial effect on some strains of Actinomycetes .

HY-147704

Antimycobacterial agent-2	Bacterial	Infection
Antimycobacterial agent-2 (compound 58) is a potent antimycobacterial agent. Antimycobacterial agent-2 shows anti-mycobacterial activities with an MIC₉₉ of 0.8 µM for Mycobacterium tuberculosis (M.tb) H37Rv. Antimycobacterial agent-2 shows cytotoxic activities with an IC₅₀ of48.1 µM for CHO cells .

HY-N9531

3'-Hydroxyxanthyletin	Bacterial	Infection
3'-Hydroxyxanthyletin is a coumarin compound with antimycobacterial activities .

HY-N9615

Azadiradione	HSP	Infection Neurological Disease Inflammation/Immunology
Azadiradione is a bioactive limonoid found in Azadirachta indica. Azadiradione is a HSF1 activator. Azadiradione has antimycobacterial, anti-nociceptive and anti-inflammatory activities .

HY-151354

Antibacterial agent 121	Bacterial	Infection
Antibacterial agent 121 (Compound 10) is an antibacterial agent. Antibacterial agent 121 shows anti-mycobacterial and anti-inflammatory activities and can be used in Tuberculosis (TB) research .

HY-112702

CRS400393	Bacterial	Infection
CRS400393 is a potent *antimycobacterial* agent, with MIC of 0.03, 2, and ≤ 0.12 µg/mL against M. abs., M. avium, M. intracellulare, and M. tuberculosis, respectively .

HY-W018811

Antibacterial agent 268	Bacterial	Infection
Antibacterial agent 268 (Compound 10e) is an antibacterial agent with antimycobacterial properties. Antibacterial agent 268 shows high anti-bacterial properties at sub-micromolar values (MIC=0.44-0.07 μM) .

HY-109587B

BM635 mesylate	Bacterial	Infection
BM635 mesylate is a MmpL3 inhibitor with outstanding anti-mycobacterial activity. BM635 mesylate has a MIC₅₀ of 0.6 μM against M. tuberculosis H37Rv. BM635 mesylate significantly improves the bioavailability compared to free-base BM635 .

HY-109587A

BM635 hydrochloride	Bacterial	Infection
BM635 hydrochloride is a MmpL3 inhibitor with outstanding anti-mycobacterial activity. BM635 hydrochloride has an MIC₅₀ of 0.08 μM against M.tuberculosis H37Rv. BM635 hydrochloride doubles the in vivo exposure with respect to the free base BM635 .

HY-P2087

Bassianolide	Insecticide Parasite Bacterial	Infection
Bassianolide is a cyclooligomer depsipeptide secondary metabolite. Bassianolide is an insecticidal virulence factor of Beauveria bassiana. Bassianolide inhibits acetylcholine-induced smooth muscle contraction, and shows moderate antiplasmodial and anti-mycobacterial activities .

HY-151205

Antituberculosis agent-3	Bacterial	Infection Inflammation/Immunology
Antituberculosis agent-3 (Compound 2) is an antituberculosis agent. Antituberculosis agent-3 shows anti-mycobacterial activity, and can inhibit M. tuberculosis H37Rv strain growth (MIC=12.5 μg/mL) .

HY-N11048

Amycolatopsin A	Bacterial	Infection Cancer
Amycolatopsin A is a 20-membered macrolide, that can be isolated from a strain of the rare actinomycete Amycolatopsis sp. MST‐108494. Amycolatopsin A shows antimycobacterial activity against Mycobacterium bovis (BCG) and M. tuberculosis (H37Rv) with IC₅₀ values of 0.4 µM and 4.4 µM, respectively .

HY-N9947A

(rac)-Methyl-6-gingerol	Antibiotic Bacterial	Infection
(rac)-Methyl-6-gingerol (Compound 14) is the racemate of Methyl-6-gingerol (HY-N9947). Methyl-6-gingerol is an antibiotic that can be isolated from Aframomum melegueta. Methyl-6-gingerol exhibits anti-mycobacterial activity by inhibiting the efflux of toxins within Mycobacterium species .

HY-165483

Nothramicin	Antibiotic Bacterial	Infection
Nothramicin is an anthracycline antibiotic with anti-mycobacterial activity .

HY-152035

Mycobacterial Zmp1-IN-1	Bacterial	Infection Inflammation/Immunology
Mycobacterial Zmp1-IN-1 is a mycobacterial zinc metalloprotease-1 (Zmp1) inhibitor. Mycobacterial Zmp1-IN-1 has anti-mycobacterial activity for Mtb H37Ra in dose-dependent inhibition. Mycobacterial Zmp1-IN-1 can be used for the research of tuberculosis (TB) .

Cat. No.	Product Name	Type

HY-B1046

Clofazimine

10+ Cited Publications

Fluorescent Dyes

Clofazimine is an orally-active anti-mycobacterial agent with a wide range of anti-mycobacterial activity including leprosy and tuberculosis. Clofazimine exerts anti-inflammatory activities and anti-tumor activities by interfering DNA replication and inhibiting IL2 (IC₅₀ = 1.10 ± 0.26 μM, Jurkat T) production. Clofazimine can be used in mycobacterial and cancer research .

HY-B1046R

Clofazimine (Standard)

Fluorescent Dyes

Clofazimine (Standard) is the analytical standard of Clofazimine. This product is intended for research and analytical applications. Clofazimine is an orally-active anti-mycobacterial agent with a wide range of anti-mycobacterial activity including leprosy and tuberculosis. Clofazimine exerts anti-inflammatory activities and anti-tumor activities by interfering DNA replication and inhibiting IL2 (IC₅₀ = 1.10 ± 0.26 μM, Jurkat T) production. Clofazimine can be used in mycobacterial and cancer research .

Cat. No.	Product Name	Type

HY-Y0030A

3-Hydroxypicolinic acid, matrix substance for MALDI-MS

3-HPA

Biochemical Assay Reagents

3-Hydroxypicolinic acid, matrix substance for MALDI-MS is a matrix. 3-Hydroxypicolinic acid, matrix substance for MALDI-MS coordinates with metal ions such as copper to form complexes with cytotoxic and antimycobacterial activity. 3-Hydroxypicolinic acid, matrix substance for MALDI-MS is used for the analysis of oligodeoxynucleotides in matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS). 3-Hydroxypicolinic acid, matrix substance for MALDI-MS is useful for nucleic acid analysis and anti-tuberculosis compound development .

Cat. No.	Product Name	Target	Research Area

HY-P2064

Lariatin A	Bacterial	Infection
Lariatins is a novel anti-mycobacterial peptides with a lasso structure produced by Rhodococcus jostii K01-B0171 .

HY-P2087

Bassianolide	Insecticide Parasite Bacterial	Infection
Bassianolide is a cyclooligomer depsipeptide secondary metabolite. Bassianolide is an insecticidal virulence factor of Beauveria bassiana. Bassianolide inhibits acetylcholine-induced smooth muscle contraction, and shows moderate antiplasmodial and anti-mycobacterial activities .

HY-125628

Kahalalide A	Endogenous Metabolite	Infection
Kahalalide A is an anti-mycobacterial compound with antimicrobial activity. Kahalalide A is derived from the marine mollusk Elysia rufescens. Kahalalide A has attracted extensive attention in natural product research due to its potential medicinal value .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0535A

Ethambutol dihydrochloride 4 Publications Verification Emb dihydrochloride	Infection Natural Products Microorganisms Classification of Application Fields Disease Research Fields	Bacterial Antibiotic
Ethambutol dihydrochloride is an antimycobacterial compound that prevents cell wall formation by inhibiting arabinosyltransferase activity. Ethambutol dihydrochloride can be used to establish animal models of hyperuricemia and optic neuropathy.

HY-W012875

3-Nitropropanoic acid 4 Publications Verification β-Nitropropionic acid; Bovinocidin	Structural Classification Microorganisms other families Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Plants Disease Research Fields Source Classification	Bacterial Apoptosis Autophagy
3-Nitropropanoic acid (β-Nitropropionic acid) is an irreversible and orally active inhibitor of succinate dehydrogenase. 3-Nitropropanoic acid exhibits potent antimycobacterial activity with a MIC value of 3.3 μM. 3-Nitropropanoic acid can induce cell apoptosis .

HY-N7030

5,7,3',4'-Tetramethoxyflavone 2 Publications Verification	Infection Flavonoids Classification of Application Fields Flavones Rutaceae Plants Disease Research Fields Murraya exotica L. Mant. Source Classification	Fungal Parasite Bacterial
5,7,3',4'-Tetramethoxyflavone, an orally active polymethoxyflavones (PMFs) that can be isolated from M. exotica, possesses various bioactivities, including anti-fungal, anti-malarial, anti-mycobacterial, and anti-inflammatory activities. 5,7,3',4'-Tetramethoxyflavone exhibits chondroprotective activity by targeting β-catenin signaling .

HY-N0941

beta-Mangostin 4 Publications Verification β-Mangostin	Infection Xanthones Classification of Application Fields Guttiferae Phenols Polyphenols Garcinia mangostana Linn. Plants Disease Research Fields Source Classification Cancer	Bacterial Parasite Apoptosis
beta-Mangostin (β-Mangostin) is a xanthone compound present in Cratoxylum arborescens, with antibacterial and antimalarial activities. beta-Mangostin exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg/mL. beta-Mangostin possesses in vitro antimalarial activity against Plasmodium falciparum, with an IC₅₀ of 3.00 μg/mL. beta-Mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic) .

HY-P2970

Stem bromelain	Ananas comosus(L.) Merr. Structural Classification Natural Products Classification of Application Fields Bromeliaceae Plants Inflammation/Immunology Disease Research Fields Cancer	Apoptosis PARP Caspase Bcl-2 Family Bacterial Interleukin Related
Stem bromelain (EC 3.4.22.32) is a cysteine protease and antibacterial agent. Stem bromelain can be isolated from the stem of the pineapple (Ananas comosus). Stem bromelain induces dose-dependent secretion of IL-12p70, and IL-6, induces Apoptosis, causes cleavage of full-length PARP protein, Caspase 3, and Caspase 9, increases Bax, and decreases Bcl-2. Stem bromelain possesses various fibrinolytic, antiedema, antithrombotic, and anti-inflammatory activities. Stem bromelain also exhibits in vivo antitumor and antileukemic activities, as well as antimetastatic effects. Stem bromelain has antimycobacterial activity. Stem bromelain provides protection against lead poisoning .

HY-N3845

Ergosterol peroxide 1 Publications Verification	Natural Products Classification of Application Fields Orchidaceae Plants Disease Research Fields Inflammation/Immunology Anoectochilus elwesii Source Classification	Bacterial
Ergosterol peroxide is a steroid derivative and can be isolated from a variety of fungi, yeast, lichens or sponges. Ergosterol peroxide has anti-tumour, proapoptotic, anti-inflammatory, anti-mycobacterial, and anti-proliferative activities .

HY-N1976

(+)-(3R,8S)-Falcarindiol 1 Publications Verification (3R,8S)-Falcarindiol; 3(R),8(S),9(Z)-Falcarindiol	Infection Structural Classification Natural Products Classification of Application Fields Decachaeta ovatifolia (DC.) R.M.King & H.Rob. Umbelliferae Plants Inflammation/Immunology Disease Research Fields Source Classification
(+)-(3R,8S)-Falcarindiol ((3R,8S)-Falcarindiol; 3 (R),8 (S),9 (Z)-Falcarindiol) is an orally active polyacetylene anti-mycobacterial agent. (+)-(3R,8S)-Falcarindiol exhibits antibacterial activity against Gram-positive bacteria, Gram-negative bacteria and mycobacteria. Co-administration of (+)-(3R,8S)-Falcarindiol with (3R)-falcarinol alters the composition of gut microbiota, reduces colonic tumor lesions and slows down polyp growth. (+)-(3R,8S)-Falcarindiol can be used in research related to tuberculosis and colorectal cancer .

HY-N1205

Spathulenol	other families Classification of Application Fields Terpenoids Sesquiterpenes Aristolochia yunnanensis Plants Aristolochiaceae Disease Research Fields Source Classification Cancer	Others
Spathulenol is isolated from Aristolochia yunnanensis, and has antioxidant, anti-inflammatory, antiproliferative and antimycobacterial activities. Spathulenol shows a high antioxidant activity with an IC₅₀ of 85.60 μg/mL in the DPPH system ^[1].

HY-129605

Ferulenol	Infection other families Classification of Application Fields Coumarins Phenylpropanoids Plants Disease Research Fields Source Classification	Oxidative Phosphorylation Mitochondrial Metabolism
Ferulenol, a sesquiterpene prenylated coumarin derivative, specifically inhibits succinate ubiquinone reductase at the level of the ubiquinonecycle. Ferulenol shows good antimycobacterial activity and haemorrhagic action .

HY-N2060

Evocarpine	Infection Alkaloids Classification of Application Fields Evodia rutaecarpa (Juss.) Benth. Rutaceae Quinoline Alkaloids Plants Inflammation/Immunology Disease Research Fields Source Classification	Apoptosis Bacterial
Evocarpine, a quinolone alkaloid that could be isolated from Evodiae fructus, inhibitss Ca ²⁺ influx through voltage-dependent calcium channels. Antimycobacterial activity .

HY-W001663

4'-Hydroxy-3'-methylacetophenone	Infection Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Rubiaceae Phenols Plants Disease Research Fields Coffea arabica L. Source Classification	Bacterial
4'-Hydroxy-3'-methylacetophenone is a phenolic volatile compound. 4'-Hydroxy-3'-methylacetophenone can be isolated from Hawaiian green coffee beans (Coffea Arabica L.). 4'-Hydroxy-3'-methylacetophenone is believed to possess potent antioxidant activity similar to that of other phenolic volatile compounds, Thymol (HY-N6810) and Eugenol (HY-N0337). 4'-Hydroxy-3'-methylacetophenone also can be used to synthesize heterocyclic compounds which have antimycobacterial activity .

HY-N8131

Pangelin	Infection other families Classification of Application Fields Coumarins Phenylpropanoids Plants Disease Research Fields Source Classification	Bacterial
Pangelin is a coumarin that can be found in Ducrosia anethifolia. Pangelin exhibits anti-mycobacterial and anti-tumor activities .

HY-N2277

3β,7β,15β-Trihydroxy-11-oxo-lanosta-8-en-24→20 lactone	Triterpenes Structural Classification Tetracyclic Triterpenoids Classification of Application Fields Terpenoids Polyporaceae Ganoderma lucidum (Leyss. Ex Fr.) Karst. Plants Inflammation/Immunology Disease Research Fields Source Classification	Bacterial
3β,7β,15β-Trihydroxy-11-oxo-lanosta-8-en-24→20 lactone is a natural compound that could be isolated from G. lucidum with antimycobacterial activity.

HY-N9947

Methyl-6-gingerol	Natural Products Aframomum melegueta K.Schum. Plants Source Classification Zingiberaceae	Bacterial Antibiotic
Methyl-6-gingerol is an antimicrobial agent derived from Aframomum melegueta that exhibits anti-mycobacterial activity by inhibiting the efflux of toxins within Mycobacterium species .

HY-N13075

Mycoplanecin A	Microorganisms Macrolide Antibiotics Antibiotics Source Classification	Antibiotic Bacterial
Mycoplanecin A is a cyclic peptide antibiotic. Mycoplanecin A has strong anti-mycobacterial, luteus, and Hypococcus activity. Mycoplanecin A also has moderate anti-Xanthomonas oryzae activity. Mycoplanecin A also has antibacterial effect on some strains of Actinomycetes .

HY-N9531

3'-Hydroxyxanthyletin	Infection other families Classification of Application Fields Coumarins Phenylpropanoids Plants Disease Research Fields Source Classification	Bacterial
3'-Hydroxyxanthyletin is a coumarin compound with antimycobacterial activities .

HY-N9615

Azadiradione	Triterpenes other families Neurological Disease Classification of Application Fields Terpenoids Plants Inflammation/Immunology Disease Research Fields Biological Pesticide Research Agricultural Research Source Classification	HSP
Azadiradione is a bioactive limonoid found in Azadirachta indica. Azadiradione is a HSF1 activator. Azadiradione has antimycobacterial, anti-nociceptive and anti-inflammatory activities .

HY-P2087

Bassianolide	Microorganisms Cyclopeptides Source Classification	Insecticide Parasite Bacterial
Bassianolide is a cyclooligomer depsipeptide secondary metabolite. Bassianolide is an insecticidal virulence factor of Beauveria bassiana. Bassianolide inhibits acetylcholine-induced smooth muscle contraction, and shows moderate antiplasmodial and anti-mycobacterial activities .

HY-N11048

Amycolatopsin A	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Disease Research Fields Cancer Source Classification	Bacterial
Amycolatopsin A is a 20-membered macrolide, that can be isolated from a strain of the rare actinomycete Amycolatopsis sp. MST‐108494. Amycolatopsin A shows antimycobacterial activity against Mycobacterium bovis (BCG) and M. tuberculosis (H37Rv) with IC₅₀ values of 0.4 µM and 4.4 µM, respectively .

HY-N1190

DL-Syringaresinol (±)-Syringaresinol	Lignans Phenylpropanoids Plants Lauraceae Lindera akoensis Hay. Source Classification	p38 MAPK AP-1 Bacterial
DL-Syringaresinol ((±)-Syringaresinol), a lignin, inhibits UVA-induced upregulation of MMP-1 by suppressing MAPK/AP-1 signaling in human HaCaT keratinocytes and dermal fibroblasts (HDFs). DL-Syringaresinol has antiphotoaging properties against UVA-induced skin aging. DL-Syringaresinol exhibits weak *antimycobacterial* activity against Mycobacterium tuberculosis H37Rv .

HY-N3700

Decarine Rutaceline	Structural Classification Alkaloids Rutaceae Plants Isoquinoline Alkaloids Zanthoxylum simulans Hance Source Classification	Bacterial HIV TNF Receptor Interleukin Related
Decarine (Rutaceline) is a benzophenanthridine alkaloid found in Zanthoxylum species. Decarinewith shows anti-inflammatory, *antimycobacterial, and anti-HIV* activity. Decarine inhibits NO, TNF-α, IL-1β, IL-6, and IL-8 production in inflammatory cell models. Decarine inhibits growth of Mycobacterium tuberculosis strains, reduces intracellular Mycobacterium tuberculosis survival, and shows low cytotoxicity toward human macrophages. Decarine inhibits HIV replication in acutely infected lymphocytes. Decarine can be used for the researches of inflammation, tuberculosis, and HIV infection .

HY-N9947A

(rac)-Methyl-6-gingerol	Zingiber officinale Roscoe Natural Products Plants Source Classification Zingiberaceae	Antibiotic Bacterial
(rac)-Methyl-6-gingerol (Compound 14) is the racemate of Methyl-6-gingerol (HY-N9947). Methyl-6-gingerol is an antibiotic that can be isolated from Aframomum melegueta. Methyl-6-gingerol exhibits anti-mycobacterial activity by inhibiting the efflux of toxins within Mycobacterium species .

HY-165483

Nothramicin	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial
Nothramicin is an anthracycline antibiotic with anti-mycobacterial activity .

HY-120733

Calpinactam FKI-4905	Natural Products Microorganisms Classification of Application Fields Disease Research Fields Inflammation/Immunology Source Classification	Bacterial Endogenous Metabolite
Calpinactam (FKI-4905), a fungal metabolite, is a new anti-mycobacterial agent.Calpinactam is active only against Mycobacteria among various microorganisms, including Gram-positive and Gram-negative bacteria, fungi and yeasts. Calpinactam inhibits the growth of Mycobacterium smegmatis and Mycobacterium tuberculosis with MIC values of 0.78 and 12.5 μg/ml, respectively .

HY-N29777

Cabraleahydroxylactone	Triterpenes Terpenoids Chisocheton penduliflorus Planch. ex Hiern Plants Meliaceae Source Classification	Parasite
Cabraleahydroxylactone is a dammarane triterpenoid with antimycobacterial activity against Mycobacterium tuberculosis .

HY-N3301

Melilotigenin C	Triterpenes Structural Classification Leguminosae Terpenoids Erythrina stricta Roxb. Plants Pentacyclic Triterpenoids Source Classification	Parasite Bacterial
Melilotigenin C can be isolated from genus Erythrina. Melilotigenin C can be used for research on antiplasmodial activity, antimycobacterial activity and cytotoxicity .

HY-N1160

Tetrahydroxysqualene	Infection Triterpenes Rhus taitensis Guill. Classification of Application Fields Terpenoids Plants Disease Research Fields Source Classification Anacardiaceae	Bacterial
Tetrahydroxysqualene is a triterpene, possessing antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 10.0 μg/mL. Tetrahydroxysqualene can be isolated from the methanolic extracts of Rhus taitensis Guill .

HY-N12823

Caprazene	Microorganisms Antibiotics Source Classification	Bacterial
Caprazene is an antimycobacterial compound and precursor molecule for semi-synthetic antibacterial antibiotics, used for studies on tuberculosis and Mycobacterium avium complex infections, which can be isolated from the acid-treated caprazamycin (CPZ) A-G mixture .

HY-N11646

Ganorbiformin B	Triterpenes Microorganisms Terpenoids Source Classification	Bacterial
Ganorbiformin B is a lanostane triterpenoid. Ganorbiformin B shares the same lanostane skeleton with known ganoderic acids. The C-3 epimer of ganoderic acid T exhibits potent antimycobacterial activity against Mycobacterium tuberculosis H37Ra .

HY-N15678

Rheoemodin 1,3,6,8-THAQ	Quinones Microorganisms Antibiotics Anthraquinones Other Antibiotics Source Classification	Bacterial
Rheoemodin is an anthraquinone and antibacterial agent. Rheoemodin can be isolated from Cordyceps morakotii BCC 56811. Rheoemodin exhibits antibacterial activity against Acinetobacter baumannii (MIC: 12.5 μg/mL). Rheoemodin also exhibits weak to moderate antimycobacterial and antifungal activity. Rheoemodin also exhibits anticancer activity against breast cancer and small cell lung cancer .

HY-W012875R

3-Nitropropanoic acid (Standard) β-Nitropropionic acid (Standard); Bovinocidin (Standard)	Structural Classification Microorganisms other families Ketones, Aldehydes, Acids Plants Source Classification	Reference Standards Bacterial Apoptosis Autophagy
3-Nitropropanoic acid (Standard) is the analytical standard of 3-Nitropropanoic acid. This product is intended for research and analytical applications. 3-Nitropropanoic acid (β-Nitropropionic acid) is an irreversible and orally active inhibitor of succinate dehydrogenase. 3-Nitropropanoic acid exhibits potent antimycobacterial activity with a MIC value of 3.3 μM. 3-Nitropropanoic acid can induce cell apoptosis[1][2].

HY-N0941R

beta-Mangostin (Standard) β-Mangostin (Standard)	Structural Classification Xanthones Guttiferae Phenols Polyphenols Garcinia mangostana Linn. Plants Source Classification	Reference Standards Bacterial Parasite Apoptosis
beta-Mangostin (Standard) is the analytical standard of beta-Mangostin. This product is intended for research and analytical applications. beta-Mangostin (β-Mangostin) is a xanthone compound present in Cratoxylum arborescens, with antibacterial and antimalarial activities. beta-Mangostin exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg/mL. beta-Mangostin possesses in vitro antimalarial activity against Plasmodium falciparum, with an IC50 of 3.00 μg/mL. beta-Mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic) .

HY-W001663R

4'-Hydroxy-3'-methylacetophenone (Standard)	Structural Classification Monophenols Ketones, Aldehydes, Acids Rubiaceae Phenols Plants Coffea arabica L. Source Classification	Reference Standards Bacterial
4'-Hydroxy-3'-methylacetophenone (Standard) is an analytical standard of 4'-Hydroxy-3'-methylacetophenone (HY-W001663). This product is intended for research and analytical applications. 4'-Hydroxy-3'-methylacetophenone is a phenolic volatile compound. 4'-Hydroxy-3'-methylacetophenone can be isolated from Hawaiian green coffee beans (Coffea Arabica L.). 4'-Hydroxy-3'-methylacetophenone is believed to possess potent antioxidant activity similar to that of other phenolic volatile compounds, Thymol (HY-N6810) and Eugenol (HY-N0337). 4'-Hydroxy-3'-methylacetophenone also can be used to synthesize heterocyclic compounds which have antimycobacterial activity .

HY-W748468

6-Isopentenyloxyisobergapten	Structural Classification Semenovia transiliensis Regel & Herder Apiaceae Coumarins Phenylpropanoids Plants Source Classification	Drug Derivative Bacterial
6-Isopentenyloxyisobergapten is a furanocoumarin found in the aerial parts of Semenovia transiliensis and the roots of Heracleum maximum. 6-Isopentenyloxyisobergapten has both selective phytotoxicity and antimycobacterial activity. 6-Isopentenyloxyisobergapten shows a minimum inhibitory concentration (MIC) of 166.5 μM and an IC₅₀ of 27.4 μM against Mycobacterium tuberculosis H37Ra. 6-Isopentenyloxyisobergapten has an IC₅₀ of 29 μM for the growth inhibition of Lemna paucicostata. 6-Isopentenyloxyisobergapten exhibits higher activity against Agrostis stolonifera than Lactuca sativa at a concentration of 1000 μM .

HY-W099725

Sarmentine	Piper longum Linn. Structural Classification Alkaloids Pyrrole Alkaloids Piperaceae Plants Source Classification	Herbicide Photosystem II
Sarmentine is a broad-spectrum contact herbicide and PSII inhibitor, with an IC₅₀ of 3.0 μM and a K_i of 1.5 μM against spinach, an IC₅₀ of 1.72 μM against wild-type Amaranthus retroflexus, and an IC₅₀ of 0.97 μM against triazine-resistant Amaranthus retroflexus. Sarmentine competitively binds to the Q_B binding site of plastoquinone on PSII, thereby blocking photosynthetic electron transport. Sarmentine inhibits enoyl-ACP reductase in Arabidopsis thaliana by targeting the early fatty acid synthesis process, with an IC₅₀ of 18.3 μM. Sarmentine induces light-independent loss of plasma membrane integrity and electrolyte leakage. Sarmentine also exhibits antiplasmodial, antimycobacterial, antituberculous, and antiplatelet aggregation activities .

Cat. No.	Product Name	Chemical Structure

HY-17025S

Rifabutin-d7
Rifabutin-d₇ is the deuterium labeled Rifabutin. Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.

HY-B0535S

Ethambutol-d4
Ethambutol-d₄ is the deuterium labeled Ethambutol. Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.

HY-B1046S

Clofazimine-d7
Clofazimine-d₇ is deuterium labeled Clofazimine. Clofazimine is an iminophenazine dye, has a marked anti-inflammatory effect, has been used in combination with other antimycobacterial agents to treat AIDS and Crohn's disease.

HY-B0688S2

Dapsone-13C12

Dapsone- ¹³C₁₂ is the ¹³C₁₂ labeled Dapsone (HY-B0688). Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

HY-133671S

Monooctyl phthalate-d4
Monooctyl phthalate-d₄ (Mono-n-octyl phthalate-d₄) is a deuterium labeled Monooctyl phthalate (HY-133671). Monooctyl phthalate (Mono-n-octyl phthalate) exhibits antimycobacterial activity with a MIC of 20 μg/mL .

HY-W013040S

Pyrazine-d4
Pyrazine-d₄ is the deuterium labeled Pyrazine . Pyrazine is an aromatic nitrogen-containing heterocyclic compound with two nitrogen atoms, and is well known for its electron-deficient property. Pyrazine serves as a key pharmacophore in a variety of drugs, and also acts as the core skeleton of derivatives with anticancer, antimycobacterial, antithrombotic and anti-inflammatory activities.

HY-B0688S1

Dapsone-d4

Dapsone-d₄ is the deuterium labeled Dapsone. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities . Dapsone?exerts effective antileprosy activity?and inhibits folate synthesis in cell extracts of?M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

HY-B0535S1

Ethambutol-d10
Ethambutol-d₁₀ is the deuterium labeled Ethambutol. Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.

HY-B0535AS

Ethambutol-d4 dihydrochloride
Ethambutol-d₄ dihydrochloride is deuterated labeled Ethambutol dihydrochloride (HY-B0535A). Ethambutol dihydrochloride is an antimycobacterial compound that prevents cell wall formation by inhibiting arabinosyltransferase activity.

HY-17025S1

Rifabutin-d6
Rifabutin-d₆ (Ansamycin-d₆) is deuterium labeled Rifabutin. Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.

HY-B0688S3

Dapsone-15N2

Dapsone- ¹⁵N₂ (4,4′-Diaminodiphenyl sulfone- ¹⁵N₂) is ¹⁵N labeled Dapsone. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities . Dapsone?exerts effective antileprosy activity?and inhibits folate synthesis in cell extracts of?M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

HY-W778649

Sarmentine-d8

Sarmentine-d₈ is the deuterium labeled Sarmentine. Sarmentine is a broad-spectrum contact herbicide and PSII inhibitor, with an IC₅₀ of 3.0 μM and a K_i of 1.5 μM against spinach, an IC₅₀ of 1.72 μM against wild-type Amaranthus retroflexus, and an IC₅₀ of 0.97 μM against triazine-resistant Amaranthus retroflexus. Sarmentine competitively binds to the Q_B binding site of plastoquinone on PSII, thereby blocking photosynthetic electron transport. Sarmentine inhibits enoyl-ACP reductase in Arabidopsis thaliana by targeting the early fatty acid synthesis process, with an IC₅₀ of 18.3 μM. Sarmentine induces light-independent loss of plasma membrane integrity and electrolyte leakage. Sarmentine also exhibits antiplasmodial, antimycobacterial, antituberculous, and antiplatelet aggregation activities .

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