1. Anti-infection
  2. Bacterial
  3. Antibacterial agent 118

Antibacterial agent 118 

Cat. No.: HY-143290
Handling Instructions

Antibacterial agent 118 (compound 20) is an antimycobacterial agent. Antibacterial agent 118 shows antibacterial activity against Mtb H37Ra, M. aurum, M. smegmatis, Mtb H37Rv and M. avium with MIC values of 40.7, 10.2, 163.0, 62.5 and 62.5 μM, respectively. Antibacterial agent 118 can be used for the research of tuberculosis.

For research use only. We do not sell to patients.

Antibacterial agent 118 Chemical Structure

Antibacterial agent 118 Chemical Structure

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Description

Antibacterial agent 118 (compound 20) is an antimycobacterial agent. Antibacterial agent 118 shows antibacterial activity against Mtb H37Ra, M. aurum, M. smegmatis, Mtb H37Rv and M. avium with MIC values of 40.7, 10.2, 163.0, 62.5 and 62.5 μM, respectively. Antibacterial agent 118 can be used for the research of tuberculosis[1].

IC50 & Target

IC50: 68 µM (Hep G2)[1]

In Vitro

Antibacterial agent 118 (1-1000 µM; 24 h) shows cytotoxicity towards Hep G2 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay[1]

Cell Line: Hep G2 cell line
Concentration: 1-1000 µM
Incubation Time: 24 hours
Result: Inhibited Hep G2 cells growth with IC50 value of 68 µM.
Molecular Weight

383.47

Formula

C19H21N5O2S

SMILES

O=C(C1=NC=CN=C1NC([[email protected]]2(CC3C4)C[[email protected]@H]4CC(C3)C2)=O)NC5=NC=CS5

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Product Name:
Antibacterial agent 118
Cat. No.:
HY-143290
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