1. Terpenoids and Glycosides
  2. Spathulenol

Spathulenol 

Cat. No.: HY-N1205
Handling Instructions

Spathulenol is isolated from Psidium guineense Sw, and has antioxidant, anti-inflammatory, antiproliferative and antimycobacterial activities. Spathulenol shows a high antioxidant activity with an IC50 of 85.60 μg/mL in the DPPH system[1].

For research use only. We do not sell to patients.

Spathulenol Chemical Structure

Spathulenol Chemical Structure

CAS No. : 6750-60-3

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Description

Spathulenol is isolated from Psidium guineense Sw, and has antioxidant, anti-inflammatory, antiproliferative and antimycobacterial activities. Spathulenol shows a high antioxidant activity with an IC50 of 85.60 μg/mL in the DPPH system[1].

In Vitro

Spathulenol exhibits a high antioxidant activity s in the DPPH and MDA system, exhibits significant DPPH free radical activity, with IC50 values of 85.60 μg/mL[1].

In Vivo

Spathulenol (oral administration; 300 mg/kg) shows a significant inhibition in the Cg-induced mice paw oedema and pleurisy model[1].
In a spontaneous lipoperoxidation rat brain homogenate model, when incubated in controlled temperature and oxygenation conditions, PG-1 exhibits a high activity with an IC50 value of 26.13 μg/mL, respectively, which is comparable to a commercial antioxidant BHT (38.41 μg/mL), Thus, PG-1 contributes to a decrease in the generation of MDA, which is a toxic product resulting from the degradation of the cell membrane by lipid peroxidation, causing cell ruptures and mutations[1].

Molecular Weight

220.35

Formula

C₁₅H₂₄O

CAS No.

6750-60-3

SMILES

O[[email protected]@]([[email protected]@]1([H])[[email protected]@](C2(C)C)([H])[[email protected]@]2([H])CC3)(C)CC[[email protected]@]1([H])C3=C

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

SpathulenolOthersPG-1 paw oedema pleurisyntioxidantInhibitorinhibitorinhibit

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