Antituberculosis agent-7
Antituberculosis agent-7, an oxetanyl-quinoline derivative, has shown good antibacterial activity against P. mirabilis with a MIC of 31.25 μM. Antituberculosis agent-7 shows good antifungal activity against A. niger with a MIC of 62.5 μM. Antituberculosis agent-7 shows excellent antimycobacterial activity with MIC 3.41 μM for M. tuberculosis H37Rv.
For research use only. We do not sell to patients.
- CAS No.: 2874263-73-5
- Formula: C26H19F4NO3
- Molecular Weight:469.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Antituberculosis agent-7 (compound 9h) has MICs of >250 μM, 250 μM, >250 μM, 250 μM for E. coli, B. subtilis, S. albus, C. albicans, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2874263-73-5
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Molecular Weight 469.43
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Formula C26H19F4NO3
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SMILES
CC1=NC2=C(C=CC=C2C=C1OC3=C(C(F)=CC=C3)C4(COC4)OCC5=CC(F)=CC(F)=C5)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Abhijit Shinde, et al. Synthesis, Characterization, and Antimicrobial Activity Screening of Some Novel 3-(2-(3-(Substituted benzyloxy)oxetan-3-yl)-3-fluorophenoxy)-8-fluoro-2-methylquinoline Derivatives as Potential Antimycobacterial Agents. ACS Omega. 2022 Dec 6;7(50):47096-47107. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antituberculosis agent-7 Related Classifications
HY-152137 Related Classifications
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