Antimycobacterial agent-12
Antimycobacterial agent-12 (Compound Ec42), a derivative of Platensimycin (HY-127146), is a dual-functional inhibitor KasA and KasB. Antimycobacterial agent-12 has antibacterial activity with a MICs of 2, 2 and 4 μg/mL against Staphylococcus aureus ATCC 29213, Mycobacterium smegmatis and its Isoniazid (HY-B0329)-resistant strain, respectively. Antimycobacterial agent-12 has a superior antimycobacterial activity in M. smegmatis-infected mouse models. Antimycobacterial agent-12 can be used for tuberculosis research.
For research use only. We do not sell to patients.
- Formula: C36H35NO7S
- Molecular Weight:625.73
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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Molecular Weight 625.73
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Formula C36H35NO7S
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SMILES
O=C(NC1=C(C(C(O)=O)=CC=C1O)O)CC[C@@]2(C(C(SC3=CC=C(C=C3)C4=CC=CC=C4)=C[C@]56[C@H]2[C@@H](O[C@]7(C6)C)C[C@H]7C5)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antimycobacterial agent-12 Related Classifications
HY-175987 Related Classifications
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