Fudapirine
Based on 1 Customer Validation
Fudapirine, an anti-tuberculosis agent, displays excellent anti-mycobacterial activity against M. tuberculosis H37Rv and low cytotoxicity. Fudapirine exhibits potent activity with MIC50s of 0.083 and 0.11 μg/mL for agent susceptible tuberculosis (DS-TB) and multidrug resistant tuberculosis (MDR-TB) strains. Fudapirine also inhibits hERG channel with the IC50 of 1.89 μM.
For research use only. We do not sell to patients.
- Purity: 95.0%
- CAS No.: 1859978-72-5
- Formula: C34H33ClN2O2
- Molecular Weight:537.09
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Antibiotic Isoforms
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Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1859978-72-5
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Appearance Solid
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Molecular Weight 537.09
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Formula C34H33ClN2O2
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Color White to off-white
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SMILES
CN(C)CC[C@@](O)(C1=CC=CC2=C1C=CC=C2)[C@H](C3=CC=CC=C3)C4=C(N=CC(C5=CC=C(C=C5)Cl)=C4)OC
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Synonyms
WX-081
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 25 mg/mL (46.55 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8619 mL | 9.3094 mL | 18.6189 mL | 46.5471 mL |
| 5 mM | 0.3724 mL | 1.8619 mL | 3.7238 mL | 9.3094 mL | |
| 10 mM | 0.1862 mL | 0.9309 mL | 1.8619 mL | 4.6547 mL | |
| 15 mM | 0.1241 mL | 0.6206 mL | 1.2413 mL | 3.1031 mL | |
| 20 mM | 0.0931 mL | 0.4655 mL | 0.9309 mL | 2.3274 mL | |
| 25 mM | 0.0745 mL | 0.3724 mL | 0.7448 mL | 1.8619 mL | |
| 30 mM | 0.0621 mL | 0.3103 mL | 0.6206 mL | 1.5516 mL | |
| 40 mM | 0.0465 mL | 0.2327 mL | 0.4655 mL | 1.1637 mL |
Fudapirine Related Classifications
HY-146158 Related Classifications
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