1. Anti-infection
    Membrane Transporter/Ion Channel
  2. Bacterial
    Potassium Channel
    Antibiotic
  3. WX-081

WX-081 

Cat. No.: HY-146158
Handling Instructions

WX-081, an anti-tuberculosis agent, displays excellent anti-mycobacterial activity against M. tuberculosis H37Rv and low cytotoxicity. WX-081 exhibits potent activity with MIC50s of 0.083 and 0.11 μg/mL for drug susceptible tuberculosis (DS-TB) and multidrug resistant tuberculosis (MDR-TB) strains. WX-081 also inhibits hERG channel with the IC50 of 1.89 μM.

For research use only. We do not sell to patients.

WX-081 Chemical Structure

WX-081 Chemical Structure

CAS No. : 1859978-72-5

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Description

WX-081, an anti-tuberculosis agent, displays excellent anti-mycobacterial activity against M. tuberculosis H37Rv and low cytotoxicity. WX-081 exhibits potent activity with MIC50s of 0.083 and 0.11 μg/mL for drug susceptible tuberculosis (DS-TB) and multidrug resistant tuberculosis (MDR-TB) strains. WX-081 also inhibits hERG channel with the IC50 of 1.89 μM[1].

Molecular Weight

537.09

Formula

C34H33ClN2O2

CAS No.
SMILES

CN(C)CC[[email protected]@](O)(C1=CC=CC2=C1C=CC=C2)[[email protected]](C3=CC=CC=C3)C4=C(N=CC(C5=CC=C(C=C5)Cl)=C4)OC

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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WX-081
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HY-146158
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