1. Anti-infection
  2. Bacterial
  3. Antibacterial agent 121

Antibacterial agent 121 

Cat. No.: HY-151354
Handling Instructions

Antibacterial agent 121 (Compound 10) is an antibacterial agent. Antibacterial agent 121 shows anti-mycobacterial and anti-inflammatory activities and can be used in Tuberculosis (TB) research.

For research use only. We do not sell to patients.

Antibacterial agent 121 Chemical Structure

Antibacterial agent 121 Chemical Structure

CAS No. : 474099-18-8

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Description

Antibacterial agent 121 (Compound 10) is an antibacterial agent. Antibacterial agent 121 shows anti-mycobacterial and anti-inflammatory activities and can be used in Tuberculosis (TB) research[1].

In Vitro

Antibacterial agent 121 (0.2-200 µM; 24 h) inhibits M. tuberculosis H37Rv growth in bacterial culture[1].
Antibacterial agent 121 (0-200 µM; 24 h) inhibits NO production in LPS-stimulated RAW 264.7 cell cultures with an IC50 value of 4.1 µM[1].
Antibacterial agent 121 (6.25-200 µM, 24 h) inhibits TNF-α and IL-1β production in LPS-stimulated macrophages[1].
Antibacterial agent 121 (25-100 µM, 4 d) inhibits M. tuberculosis M299 with an MIC50 value of 24.8 µM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: M. tuberculosis H37Rv
Concentration: 0.2-200 µM
Incubation Time: 24 hours
Result: Inhibited Mtb H37Rv growth with MIC50 of 8.6 µM.

Cell Viability Assay[1]

Cell Line: RAW 264.7 macrophages and J774A.1 macrophages
Concentration: 6.25-200 µM
Incubation Time: 24 hours
Result: Showed IC50 values of 15.3 µM and 28.4 µM for TNF-α and IL-1β production, respectively.
Molecular Weight

346.44

Formula

C18H22N2O3S

CAS No.
SMILES

S=C(NC1=CC(OC)=C(OC)C(OC)=C1)NCCC2=CC=CC=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Antibacterial agent 121
Cat. No.:
HY-151354
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