1. Anti-infection
  2. Bacterial
  3. BM635 hydrochloride

BM635 hydrochloride 

Cat. No.: HY-109587A
Handling Instructions

BM635 hydrochloride is a MmpL3 inhibitor with outstanding anti-mycobacterial activity. BM635 hydrochloride has an MIC50 of 0.08 μM against M.tuberculosis H37Rv. BM635 hydrochloride doubles the in vivo exposure with respect to the free base BM635.

For research use only. We do not sell to patients.

BM635 hydrochloride Chemical Structure

BM635 hydrochloride Chemical Structure

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Other In-stock Forms of BM635 hydrochloride:

Other Forms of BM635 hydrochloride:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

BM635 hydrochloride is a MmpL3 inhibitor with outstanding anti-mycobacterial activity. BM635 hydrochloride has an MIC50 of 0.08 μM against M.tuberculosis H37Rv. BM635 hydrochloride doubles the in vivo exposure with respect to the free base BM635[1].

IC50 & Target

MIC50: 0.08 μM (M. tuberculosis H37Rv)[1]

In Vivo

BM635 hydrochloride (oral administration; 50 mg/Kg) results in gradual elevations in blood up to a Cmax of 579.1 ng/ml with Tmax of 3 hour. It doubles the in vivo exposure with respect to the free base BM635 in C57BL/6J mice[1].

Molecular Weight

428.97

Formula

C₂₅H₃₀ClFN₂O

SMILES

CC(C1=CC=C(C2=CC(CN3CCOCC3)=C(C)N2C4=CC=C(F)C=C4)C=C1)C.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

BM635BM 635BM-635Bacterialanti-mycobacterialM.tuberculosisMycobacteriumInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product name:
BM635 hydrochloride
Cat. No.:
HY-109587A
Quantity:
MCE Japan Authorized Agent: