2. Anti-infection
  3. Bacterial Parasite
  4. Antimycobacterial agent-4

Antimycobacterial agent-4 is a 2-amino-4-(2-pyridyl) thiazole derivative, with antimycobacterial activity, antiplasmodial activity, and cytotoxicity on a mammalian cell line.

For research use only. We do not sell to patients.

Antimycobacterial agent-4 Chemical Structure

Antimycobacterial agent-4 Chemical Structure

CAS No. : 476319-66-1

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Based on 1 publication(s) in Google Scholar

Antimycobacterial agent-4 Related Antibodies

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Description

Antimycobacterial agent-4 is a 2-amino-4-(2-pyridyl) thiazole derivative, with antimycobacterial activity, antiplasmodial activity, and cytotoxicity on a mammalian cell line[1][2].

IC50 & Target

Plasmodium

 

In Vitro

Antimycobacterial agent-4 (compound 12) exerts antimycobacterial activity against the Mycobacterium tuberculosis H37Rv strain (MIC99=5 μM), and antiplasmodial activity against the Chloroquine (HY-17589A) sensitive NF54 Plasmodium falciparum strain (IC50=6.1 μM) and cytotoxicity on a mammalian cell line (CHO, IC50=2.2 μM)[1].
Antimycobacterial agent-4 (compound 38) shows cytotoxicity against Vero cells with toxic concentration TC50 of 3.0 μM[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antimycobacterial agent-4 Related Antibodies
Molecular Weight

326.33

Formula

C15H10N4O3S
CAS No.
Appearance

Solid

Color

Off-white to yellow

SMILES

O=C(NC1=NC(C2=NC=CC=C2)=CS1)C3=CC=C([N+]([O-])=O)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
References
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Antimycobacterial agent-4 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antimycobacterial agent-4476319-66-1Antimycobacterial agent4Antimycobacterial agent 4BacterialParasite2-amino-4-(2-pyridyl) thiazoleantimycobacterialantiplasmodialcytotoxicitychloroquine sensitiveNF54 strainH37Rv strainInhibitorinhibitorinhibit

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