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  3. Anti-inflammatory agent 15

Anti-inflammatory agent 15 

Cat. No.: HY-144737
Handling Instructions

Anti-inflammatory agent 15 (compound 29) is a potent antimycobacterial and anti-inflammatory agent. Anti-inflammatory agent 15 inhibits Mtb H37Rv and M299 growth, with MIC50 (minimum inhibitory concentration 50%) of 2.3 and 7.8 μM, respectively. Anti-inflammatory agent 15 inhibits NO through the suppression of iNOS expression, and also inhibited the production of TNF-α and IL-1β. Anti-inflammatory agent 15 can be used for tuberculosis (TB) research.

For research use only. We do not sell to patients.

Anti-inflammatory agent 15 Chemical Structure

Anti-inflammatory agent 15 Chemical Structure

CAS No. : 474516-87-5

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Description

Anti-inflammatory agent 15 (compound 29) is a potent antimycobacterial and anti-inflammatory agent. Anti-inflammatory agent 15 inhibits Mtb H37Rv and M299 growth, with MIC50 (minimum inhibitory concentration 50%) of 2.3 and 7.8 μM, respectively. Anti-inflammatory agent 15 inhibits NO through the suppression of iNOS expression, and also inhibited the production of TNF-α and IL-1β. Anti-inflammatory agent 15 can be used for tuberculosis (TB) research[1].

IC50 & Target

TNF-α

 

In Vitro

Anti-inflammatory agent 15 (compound 29) is active in the reduction of accumulated nitrite, with an IC50 of 71.7 ± 1.1 μM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

284.42

Formula

C17H20N2S

CAS No.
SMILES

S=C(NCC1=CC=CC=C1)NC2=CC=C(C(C)C)C=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Anti-inflammatory agent 15
Cat. No.:
HY-144737
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