474516-87-5
Chemical Structure
Anti-inflammatory agent 15
- CAS No.: 474516-87-5
- Formula:C17H20N2S
- Molecular Weight:284.42
IUPAC Name: 1-benzyl-3-(4-isopropylphenyl)thiourea
InChIKey: XLHNUFJSOUSSBA-UHFFFAOYSA-N
SMILES: S=C(NCC1=CC=CC=C1)NC2=CC=C(C(C)C)C=C2
Biological Activity: Anti-inflammatory agent 15 (compound 29) is a potent antimycobacterial and anti-inflammatory agent. Anti-inflammatory agent 15 inhibits Mtb H37Rv and M299 growth, with MIC50 (minimum inhibitory concentration 50%) of 2.3 and 7.8 μM, respectively. Anti-inflammatory agent 15 inhibits NO through the suppression of iNOS expression, and also inhibited the production of TNF-α and IL-1β. Anti-inflammatory agent 15 can be used for tuberculosis (TB) research[1].
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Anti-inflammatory agent 15 | Anti-inflammatory agent 15 (compound 29) is a potent antimycobacterial and anti-inflammatory agent. Anti-inflammatory agent 15 inhibits Mtb H37Rv and M299 growth, with MIC50 (minimum inhibitory concentration 50%) of 2.3 and 7.8 μM, respectively. Anti-inflammatory agent 15 inhibits NO through the suppression of iNOS expression, and also inhibited the production of TNF-α and IL-1β. Anti-inflammatory agent 15 can be used for tuberculosis (TB) research. | |||||||||||||||||||||
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Keywords
