MtMetAP1-IN-1
MtMetAP1-IN-1 is an inhibitor of Mycobacterium tuberculosis (Mtb), targeting methionine aminopeptidase 1 (MetAP1). MtMetAP1-IN-1 exerts antimycobacterial activity.
For research use only. We do not sell to patients.
- Formula: C15H10BrN5O2S
- Molecular Weight:404.24
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
methionine aminopeptidase 1 (MetAP1)[1]
MetAP1 is known to work in the presence of various divalent cations, is considered to acts function with a most probable cofactor, iron (Fe2+)[1].
MtMetAP1-IN-1 (compound 12) (12.5 μM) inhibits MtMetAP1 under different metals catalytic effect with residual activity RA (%) of 51% (Co2+), 21% (Ni2+), 33% (Fe2+)[1].
MtMetAP1-IN-1 has a preference towards Ni2+, inhibits MtMetAP1 with an IC50 value of with 0.7 μM [1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 404.24
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Formula C15H10BrN5O2S
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SMILES
O=C(C1=NC=CN=C1NC(C2=C(C=CC=C2)Br)=O)NC3=NC=CS3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MtMetAP1-IN-1 Related Classifications
HY-143249 Related Classifications
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