166 Results for "

Penicillium

" in MedChemExpress (MCE) Product Catalog:
Products (166)

166 Results for "Penicillium" in MCE Product Catalog:

27
27 Publications Verification
Cat. No.: HY-W250119
CAS No.: 23411-34-9
Synonyms: EDTA disodium calcium salt hydrate; Ethylenediaminetetraacetic acid disodium calcium salt hydrate
Calcium disodium edetate hydrate (EDTA disodium calcium salt hydrate) is a metal chelator and antifungal agent. Calcium disodium edetate hydrate chelates Mn 2+, damages mitochondria, and interferes with carbohydrate metabolic pathways, particularly the synthesis of pyruvate in glycolysis. Calcium disodium edetate hydrate inhibits Penicillium digitatum and delays conidial germination. Calcium disodium edetate (hydrate) enhances the host defense system of citrus fruits. Calcium disodium edetate hydrate is applicable to research related to citrus green mold .
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11
11 Cited Publications
Cat. No.: HY-N6778
CAS No.: 57186-25-1
Paxilline is an indole alkaloid mycotoxin derived from Penicillium paxilli, which effectively inhibits the BK channel through a channel-blocking mechanism. Paxilline also inhibits sarco/endoplasmic reticulum Ca 2+-stimulated ATPase (SERCA), with IC50 values ranging from 5 μM to 50 μM for different SERCA isoforms. Paxilline exhibits significant anticonvulsant and neuroprotective effects, as well as certain antioxidant activity .
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6
6 Cited Publications
Cat. No.: HY-B1747
CAS No.: 1121-30-8
Research Areas:  

Infection

Pyrithione is an inhibitor of membrane transport processes in fungi. Pyrithione is a potent antibiotic aspergillic acid. Pyrithion incubated Penicillium mycelia would have a marked decrease in the activities of a variety of independently regulated transport systems .
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4
4 Cited Publications
Cat. No.: HY-N6779
CAS No.: 149-29-1
Synonyms: Terinin
Patulin (Terinin) is a mycotoxin produced by fungi including the Aspergillus, Penicillium, and Byssochlamys species, causes chromosome breakage, mutation, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage .
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3
3 Cited Publications
Cat. No.: HY-W093399
CAS No.: 1066-33-7
Ammonium bicarbonate,AR,99% is an analytical reagent-grade ammonium bicarbonate. Ammonium bicarbonate has antifungal activity. Ammonium bicarbonate is widely used in laboratory analysis, food processing, agricultural fertilization and other fields .
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3
3 Cited Publications
Cat. No.: HY-117235
CAS No.: 2050-87-5
Purity:  99.20%
Diallyl Trisulfide is an orally active anticancer agent that can be isolated from garlic. Diallyl Trisulfide has the ability to induce apoptosis and exhibits anticancer, anti-inflammatory, antioxidant, and antibacterial activities. Diallyl Trisulfide can be used to study a variety of cancers, including liver, colon and prostate cancer .
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1
1 Cited Publications
Cat. No.: HY-30220
CAS No.: 20312-36-1
Synonyms: L-(-)-3-Phenyllactic Acid
(S)-2-Hydroxy-3-phenylpropanoic acid is the L-configuration of 2-Hydroxy-3-phenylpropanoic acid, and its level is closely related to some diseases, such as phenylketonuria .
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1
1 Cited Publications
Cat. No.: HY-N6777
CAS No.: 90-65-3
Penicillic acid is a polyketide mycotoxin produced by several species of Aspergillus and Penicillium. Penicillic acid exhibits cytotoxicity in rat alveolar macrophages (AM) in vitro. Penicillic acid inhibits Fas ligand-induced apoptosis by blocking self-processing of caspase-8 .
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1
1 Cited Publications
Cat. No.: HY-N6748
CAS No.: 58735-64-1
Roquefortine C is a mycotoxin that can be isolated from Penicillium species. Roquefortine C is an agonist of P-gp and an inhibitor of P450 3A and P450 1A. Roquefortine C can inhibit Gram-positive bacteria and also has certain neurotoxicity. Additionally, Roquefortine C can exert antitumor activity .
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1
1 Cited Publications
Cat. No.: HY-N0535
CAS No.: 6681-18-1
Synonyms: Magnoflorine chloride; α-Magnoflorine chloride; Thalictrine chloride
(+)-Magnoflorine (α-Magnoflorine) chloride is an orally active aporphine alkaloid with multiple biological activities. (+)-Magnoflorine chloride promotes Parkin/PINK1-mediated mitochondrial autophagy, inhibits the activation of NLRP3/Caspase-1 pathway, regulates the intestinal microbiota, and exhibits significant anti-inflammatory and immunomodulatory activities. (+)-Magnoflorine chloride inhibits JNK and TLR4/NF-κB signaling pathways, activates Sirt1/AMPK pathway, alleviates neuronal oxidative stress and apoptosis. Magnoflorine chloride upregulates miR-410-3p, inhibits HMGB1/NF-κB pathway, and has anti-tumor activity. (+)-Magnoflorine chloride also has significant antifungal activity .
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1
1 Cited Publications
Cat. No.: HY-P2963
CAS No.: 54576-84-0
Target:  

Endonuclease

Research Areas:  

Others

Nuclease P1 is a single-stranded specific endonuclease, it hydrolyzes nucleic acids into 5'-mononucleotides and cleaves the single-stranded region of a double-stranded nucleic acid. Nuclease P1 is one of the most well-known single stranded specific nucleases in the field of molecular biology, it is widely used in the pharmaceutical and food industries . Nuclease P1 can be obtained by fermentation of Penicillium citrinum: through extraction process, ultrafiltration concentration, drying and purification, etc.
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Cat. No.: HY-170035
CAS No.: 95119-86-1
Synonyms: C18 Glucosyl(β) ceramide (d18:1/18:0); D-glucosyl-β-1,1' N-stearoyl-D-erythro-sphingosine
Target:  

Fungal Wnt β-catenin

Research Areas:  

Infection Neurological Disease Cancer

GlcCer (d18:1/18:0) (C18 Glucosyl(β) ceramide (d18:1/18:0)) is a glycosphingolipids that activates the Wnt/β-catenin pathway by targeting LRP6. GlcCer (d18:1/18:0) drives EMT, migration, invasion and GBA1-mediated liver cancer metastasis. GlcCer (d18:1/18:0) accumulates to impair lysosomal function and induce toxic α-synuclein aggregation. GlcCer (d18:1/18:0) supports growth, sporulation, germination and virulence in Penicillium digitatum. GlcCer (d18:1/18:0) is reduced in demyelinated mouse corpus callosum. GlcCer (d18:1/18:0) can be used for the research of liver cancer, synucleinopathies, fungal, Parkinson’s disease and Gaucher disease .
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Cat. No.: HY-W099579
CAS No.: 79725-98-7
Synonyms: Kojic dipalmitate
Target:  

Tyrosinase

Research Areas:  

Endocrinology

Kojic acid dipalmitate (Kojic dipalmitate) is a derivative of Kojic acid (HY-W050154), a fungal metabolite that can be produced by species of Aspergillus, Acetobacter and Penicillium. Kojic acid dipalmitate is a slow and reversible competitive inhibitor of tyrosinase. Kojic acid dipalmitate can be used for skin‐lightening agent research .
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Cat. No.: HY-W001084
CAS No.: 14199-15-6
Methyl 4-hydroxyphenylacetate is a compound found in the marine fungus Penicillium oxalicum 0312F1. Methyl 4-hydroxyphenylacetate can be Methyl 4-hydroxyphenylacetate inhibits replication of tobacco mosaic virus (TMV) in Nicotiana tabacum leaf discs. Methyl 4-hydroxyphenylacetate shows inhibitory activity against proliferation of cancer cells. Methyl 4-hydroxyphenylacetate can be used for the researches of TMV infection and cancer .
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Cat. No.: HY-75564
CAS No.: 4526-77-6
Cyclo(Ala-Gly), a metabolite of a mangrove endophytic fungus, Penicillium thomi, exhibits cytotoxicity against A549, HepG2 and HT29 cells. The IC50 values range from 9.5 to 18.1 μM .
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Cat. No.: HY-N10220
CAS No.: 125600-53-5
Paraherquamide E is a paraherquamide alkaloid and 14C-deshydroxy paraherquamide analog found in Aspergillus aculeatus GC-147‑5 and Penicillium charlesii, with insecticidal and reproductive toxicant activity, high selectivity, and negligible toxicity to nontarget ladybugs .Paraherquamide E disrupts fatty acid synthesis, inhibits vitellogenin production, alters metabolic homeostasis, induces ovarian abnormalities, and causes Asian citrus psyllid mortality, while remaining inactive against Asian citrus psyllid cholinergic systems .
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Cat. No.: HY-N11955
CAS No.: 91741-17-2
Cyclo(Ile-Leu) is a Alkaloids product that can be isolated from From Penicillium oxalicum .
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Cat. No.: HY-126983
CAS No.: 206978-14-5
Purity:  97.20%
Synonyms: Epoxybergamottin
6',7'-Epoxybergamottin is a metabolism of Penicillium digitatum. 6',7'-Epoxybergamottin can be used in study the cytochrome P450 3A4 inhibitory activity .
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Cat. No.: HY-126484
CAS No.: 60048-73-9
Target:  

Fungal

Eremofortin B is a sesquiterpenoid compound synthesized by penicillium roqueforti PR Toxin (PRT) .
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Cat. No.: HY-116479
CAS No.: 478-60-4
Citromycetin is an aromatic polyketide compound from Australian marine-derived and terrestrial Penicillium spp .
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