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Art. -Nr.: HY-N17436

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Demethoxyhexahydrocurcumin

Demethoxyhexahydrocurcumin is a Curcumin (HY-N0005) biotransformation metabolite and diarylheptanoid with antioxidant and antimicrobial activities. Demethoxyhexahydrocurcumin scavenges free radicals, inhibits cancer cell viability, and suppresses microbial growth. Demethoxyhexahydrocurcumin can be used for the research of colorectal cancer.

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CAS. Nr.: 138870-92-5
Formel: C₂₀H₂₄O₅
Molecular Weight:344.40

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Demethoxyhexahydrocurcumin Chemical Structure

CAS. Nr.: 138870-92-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

Demethoxyhexahydrocurcumin displays greater cytotoxic activity against CaCo-2 colorectal cancer cells^[1].
Demethoxyhexahydrocurcumin demonstrates antimicrobial activity against Staphylococcus aureus, E. coli, Candida albicans, and Aspergillus niger but does not outperform curcumin in the disc diffusion assay^[1].
Demethoxyhexahydrocurcumin exhibits potent antioxidant activity (IC₅₀ of 8.62 μg/mL)^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS. Nr. 138870-92-5
Molecular Weight 344.40
Formel C₂₀H₂₄O₅
SMILES

O=C(CC(CCC1=CC=C(C=C1)O)O)CCC2=CC=C(C(OC)=C2)O
Structure Classification
- Phenols
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Nurul Iman Aminudin, et al. Biotransformation of curcumin and structure-activity relationship (SAR) of its analogues: A systematic review. Biocatalysis and Biotransformation 11 May 2022.

[2]. A. Younis, et al. Microbial Transformation of Curcumin and Evaluation of the Biological Activities of the Isolated Metabolites.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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