Demethoxyhexahydrocurcumin
Demethoxyhexahydrocurcumin is a Curcumin (HY-N0005) biotransformation metabolite and diarylheptanoid with antioxidant and antimicrobial activities. Demethoxyhexahydrocurcumin scavenges free radicals, inhibits cancer cell viability, and suppresses microbial growth. Demethoxyhexahydrocurcumin can be used for the research of colorectal cancer.
For research use only. We do not sell to patients.
- CAS No.: 138870-92-5
- Formula: C20H24O5
- Molecular Weight:344.40
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Demethoxyhexahydrocurcumin displays greater cytotoxic activity against CaCo-2 colorectal cancer cells[1].
Demethoxyhexahydrocurcumin demonstrates antimicrobial activity against Staphylococcus aureus, E. coli, Candida albicans, and Aspergillus niger but does not outperform curcumin in the disc diffusion assay[1].
Demethoxyhexahydrocurcumin exhibits potent antioxidant activity (IC50 of 8.62 μg/mL)[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 138870-92-5
-
Molecular Weight 344.40
-
Formula C20H24O5
-
SMILES
O=C(CC(CCC1=CC=C(C=C1)O)O)CCC2=CC=C(C(OC)=C2)O
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)