Halociline
Halociline, a derivative of alkaloids, that can be isolated from the marine fungus Penicillium griseofulvum.
Halociline targets MAPK1, MMP-9, and PIK3CA in gastric cancer cells, potentially mediated by diverse pathways including cancer, lipid metabolism, atherosclerosis, and EGFR tyrosine kinase inhibitor resistance. Halociline possesses antimicrobial, antioxidant and biofilm inhibitory activities.
For research use only. We do not sell to patients.
- CAS No.: 2977255-36-8
- Formula: C11H17NO2
- Molecular Weight:195.26
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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p38 MAP kinase |
MMP-9 |
Chemical Information
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CAS No. 2977255-36-8
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Molecular Weight 195.26
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Formula C11H17NO2
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SMILES
CC1=C(C=C(C=C1C(C(O)C)C)O)N
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Mohamed M M Abdel Razek, et al. A New Phenolic Alkaloid from Halocnemum strobilaceum Endophytes: Antimicrobial, Antioxidant and Biofilm Inhibitory Activities. Chem Biodivers. 2020 Oct;17(10):e2000496. [Content Brief]
[2]. Xiangru Zha, et al. Network pharmacology, molecular docking, and molecular dynamics simulation analysis reveal the molecular mechanism of halociline against gastric cancer. Mol Divers. 2024 Mar 19. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)