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Cat. No.: HY-N19938

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Roseopurpurin B

Roseopurpurin B is a polyketide compound found in Aspergillus aculeatus DL1011 and Penicillium roseopurpureum (CMB-MF038), with DPPH scavenging activity. Roseopurpurin B shows no cytotoxicity against human cancer cells, and exhibits no growth inhibitory activity against Gram-positive or Gram-negative bacteria.

For research use only. We do not sell to patients.

CAS No.: 1995864-56-6
Formula: C₁₉H₂₄O₈
Molecular Weight:380.39

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Roseopurpurin B Chemical Structure

CAS No.: 1995864-56-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
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Biological Activity

Description

In Vitro

Roseopurpurin B (S11) (0.00-0.16 mg/mL; 30 min) shows DPPH-scavenging activity with an IC₅₀ of approximately 165 µM in an in vitro assay^[1].
Roseopurpurin B (0.78-50 µM; 48 h) does not show cytotoxic activity against MCF-7, SNK-6, MG-63, or U-87 human cancer cell lines in an in vitro assay^[1].
Roseopurpurin B (compound 4) shows no antibacterial growth inhibitory activity against Gram-positive and Gram-negative bacteria, with an IC₅₀ > 30 μM^[2].
Roseopurpurin B is noncytotoxic toward SW620, NCI-H460, KB3-1, and HepG2 human carcinoma cell lines, with an IC₅₀ > 30 μM^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1995864-56-6
Molecular Weight 380.39
Formula C₁₉H₂₄O₈
SMILES

COC(C(C(C)=CC(O)=C1C)=C1O[C@@H]2[C@](C)([C@@H](C(C(C)=C2O)=O)O)OC)=O
Structure Classification
- Phenols
- Monophenols
Initial Source
- Microorganisms
Penicillium roseopurpureum
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Shi X, et al. Metabolomic Strategy to Characterize the Profile of Secondary Metabolites in Aspergillus aculeatus DL1011 Regulated by Chemical Epigenetic Agents. Molecules. 2022 Dec 26;28(1):218.

[2]. Shang Z, et al. Roseopurpurins: Chemical Diversity Enhanced by Convergent Biosynthesis and Forward and Reverse Michael Additions. Org Lett. 2016;18(17):4340-4343. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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