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  4. Calcium disodium edetate hydrate

Calcium disodium edetate hydrate  (Synonyms: EDTA disodium calcium salt hydrate; Ethylenediaminetetraacetic acid disodium calcium salt hydrate)

Cat. No.: HY-W250119 Purity: 98.0%
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Calcium disodium edetate hydrate (EDTA disodium calcium salt hydrate) is a metal chelator and antifungal agent. Calcium disodium edetate hydrate chelates Mn2+, damages mitochondria, and interferes with carbohydrate metabolic pathways, particularly the synthesis of pyruvate in glycolysis. Calcium disodium edetate hydrate inhibits Penicillium digitatum and delays conidial germination. Calcium disodium edetate (hydrate) enhances the host defense system of citrus fruits. Calcium disodium edetate hydrate is applicable to research related to citrus green mold.

For research use only. We do not sell to patients.

CAS No. : 23411-34-9

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Based on 24 publication(s) in Google Scholar

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Calcium disodium edetate hydrate Related Antibodies

Top Publications Citing Use of Products

    Calcium disodium edetate hydrate purchased from MedChemExpress. Usage Cited in: Nat Immunol. 2025 Oct;26(10):1660-1672.  [Abstract]

    Representative images of CHMP4–GFP puncta (arrowheads; left) and percentage of CHMP4 speckle+ (top right) or Annexin V+ (bottom right) cells in BMDMs incubated with PBS, 15 µM SK56, 2 mM EDTA or EDTA + SK56 at 2 h after the addition of 1 μg/ml LPS + 10 μM nigericin; scale bar, 50 µm; n = 5 repeats

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    Description

    Calcium disodium edetate hydrate (EDTA disodium calcium salt hydrate) is a metal chelator and antifungal agent. Calcium disodium edetate hydrate chelates Mn2+, damages mitochondria, and interferes with carbohydrate metabolic pathways, particularly the synthesis of pyruvate in glycolysis. Calcium disodium edetate hydrate inhibits Penicillium digitatum and delays conidial germination. Calcium disodium edetate (hydrate) enhances the host defense system of citrus fruits. Calcium disodium edetate hydrate is applicable to research related to citrus green mold[1][2].

    In Vitro

    Calcium disodium edetate hydrate (3.125-50 mmol L−1) completely inhibits hyphal growth of Penicillium digitatum strain P44 in vitro, with an MIC/MFC of 50 mmol L−1[2].
    Calcium disodium edetate hydrate (12.5-50 mmol L-1; 8-12 h) dose-dependently delays and inhibits conidial germination of Penicillium digitatum strain P44 in vitro[2].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Calcium disodium edetate hydrate Related Antibodies
    In Vivo

    Edetate calcium disodium hydrate (25-250 mmol L-1; intralesional injection) reduces the incidence of citrus green mold and decreases lesion size in a dose-dependent manner[2].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
    Formula

    C10H12CaN2O8.xH2O.2Na
    CAS No.
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    O=C1[O-][Ca+2]([N]2(C1)CC3=O)([O-]3)([O-]C4=O)([O-]5)[N](C4)(CC2)CC5=O.[Na+].[x].[Na+].O
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    4°C, sealed storage, away from moisture and light

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

    Solvent & Solubility
    In Vitro: 

    H2O : ≥ 125 mg/mL

    *"≥" means soluble, but saturation unknown.

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    Calcium disodium edetate hydrate Related Classifications

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Calcium disodium edetate23411-34-9EDTA disodium calcium saltEthylenediaminetetraacetic acid disodium calcium saltBiochemical Assay ReagentsFungalMitochondrial Metabolismlead poisoningcalciummagnesiummitochondriaironglycolytic pyruvate synthesisglomerular filtrationzincPenicillium digitatumcitrus green moldInhibitorinhibitorinhibit

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